• Clinical responses following inspiratory muscle training in exercise-induced laryngeal obstruction 

      Sandnes, Astrid; Andersen, Tiina Maarit; Clemm, Hege Synnøve Havstad; Hilland, Magnus; Heimdal, John-Helge; Halvorsen, Thomas; Røksund, Ola Drange; Vollsæter, Maria (Journal article; Peer reviewed, 2021)
      Purpose Exercise-induced laryngeal obstruction (EILO) is relatively common in young people. Treatment rests on poor evidence; however, inspiratory muscle training (IMT) has been proposed a promising strategy. We aimed to ...
    • Conundrums in the breathless athlete; exercise-induced laryngeal obstruction or asthma? 

      Jansrud, Ida; Halvorsen, Thomas; Vollsæter, Maria; Hilland, Magnus; Heimdal, John-Helge; Røksund, Ola Drange; Clemm, Hege Synnøve Havstad (Journal article; Peer reviewed, 2022)
      Purpose: Exercise-induced bronchoconstriction (EIB) and exercise-induced laryngeal obstruction (EILO) are the two disorders commonly considered when athletes complain of exertional dyspnea. They are highly different but ...
    • Exercise induced laryngeal obstructions in humans and equines. A comparative review 

      Fretheim-Kelly, Zoe Louise; Halvorsen, Thomas; Clemm, Hege Synnøve Havstad; Roksund, Ola Drange; Heimdal, John-Helge; Vollsæter, Maria; Fintl, Constanze; Strand, Eric (Peer reviewed; Journal article, 2019-10-30)
      Dynamic obstructions of the larynx are a set of disorders that occur during exercise in equines and humans. There are a number of similarities in presentation, diagnosis, pathophysiology and treatment. Both equines and ...
    • Exercise inducible laryngeal obstruction: diagnostics and management 

      Røksund, Ola Drange; Heimdal, John-Helge; Clemm, Hege Synnøve Havstad; Vollsæter, Maria; Halvorsen, Thomas (Peer reviewed; Journal article, 2017-01)
      Obstruction of the central airways is an important cause of exercise-induced inspiratory symptoms (EIIS) in young and otherwise healthy individuals. This is a large, heterogeneous and vastly understudied group of patients. ...
    • Exercise-induced laryngeal obstruction in athletes treated with inspiratory muscle training 

      Sandnes, Astrid; Andersen, Tiina Maarit; Clemm, Hege Synnøve Havstad; Hilland, Magnus; Vollsæter, Maria; Heimdal, John-Helge; Eide, Geir Egil; Halvorsen, Thomas; Røksund, Ola Drange (Peer reviewed; Journal article, 2019-01-18)
      Background Exercise-induced laryngeal obstruction (EILO) is common in athletes and presents with dyspnoea, chest tightness, inspiratory stridor and sometimes panic reactions. The evidence for conservative treatment is weak, ...
    • Exercise-induced laryngeal obstruction: natural history and effect of surgical treatment 

      Maat, Robert Christiaan; Hilland, Magnus; Røksund, Ola Drange; Halvorsen, Thomas; Olofsson, Jan; Aarstad, Hans Jørgen; Heimdal, John-Helge (Peer reviewed; Journal article, 2011-06-05)
      The current follow-up study concerning the supraglottic type of exercise-induced laryngeal obstruction (EILO) was performed to reveal the natural history of supraglottic EILO and compare the symptoms, as well as the laryngeal ...
    • Exercise-induced Laryngeal Obstruction: Protocol for a Randomized Controlled Treatment Trial 

      Clemm, Hege Synnøve Havstad; Røksund, Ola Drange; Andersen, Tiina Maarit; Heimdal, John-Helge; Karlsen, Tom; Hilland, Magnus; Fretheim-Kelly, Zoe; Hufthammer, Karl Ove; Sandnes, Astrid; Hjelle, Sigrun Margrethe; Vollsæter, Maria; Halvorsen, Thomas (Journal article; Peer reviewed, 2022)
      Background: Exercise-induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young individuals, caused by paradoxical inspiratory adduction of laryngeal structures, and diagnosed by ...
    • Feasibility and tolerability of measuring translaryngeal pressure during exercise 

      Kelly, Zoe Louise; Halvorsen, Thomas; Heimdal, John-Helge; Strand, Eric; Vollsæter, Maria; Clemm, Hege Synnøve Havstad; Røksund, Ola Drange (Peer reviewed; Journal article, 2019)
      Objectives/Hypothesis: To determine if simultaneous tracheal and supraglottic pressure measurement performed during a continuous laryngoscopy exercise (CLE) test is possible, tolerable, and feasible, and if so, whether ...
    • Impact of EMG Changes in Continuous Vagal Nerve Monitoring in High-Risk Endocrine Neck Surgery 

      Brauckhoff, Katrin; Vik, Renate Kollevåg; Sandvik, Lorentz; Heimdal, John-Helge; Aas, Turid; Biermann, Martin; Brauckhoff, Michael (Peer reviewed; Journal article, 2016-03)
      Background: Continuous vagal intraoperative neuromonitoring (CIONM) of the recurrent laryngeal nerve (RLN) may reduce the risk of RLN lesions during high-risk endocrine neck surgery such as operation for large goiter ...
    • In vitro-stimulated IL-6 monocyte secretion and in vivo peripheral blood T lymphocyte activation uniquely predicted 15-year survival in patients with head and neck squamous cell carcinoma 

      Aarstad, Helene Hersvik; Vintermyr, Olav Karsten; Ulvestad, Elling; Kross, Kenneth Wilfried; Heimdal, John-Helge; Aarstad, Hans Jørgen (Peer reviewed; Journal article, 2015-06-16)
      The study was performed in order to determine whether peripheral blood monocyte in vitro function, and lymphocyte in vivo activation at diagnosis, was associated with HPV tumor infection status and 15-year survival in head ...
    • Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis 

      Andersen, Tiina Maarit; Sandnes, Astrid; Brekka, Anne Kristine; Hilland, Magnus; Clemm, Hege; Fondenes, Ove; Tysnes, Ole Bjørn; Heimdal, John-Helge; Halvorsen, Thomas; Vollsæter, Maria; Røksund, Ola Drange (Peer reviewed; Journal article, 2017)
      Background: Most patients with amyotrophic lateral sclerosis (ALS) are treated with mechanical insufflation–exsufflation (MI-E) in order to improve cough. This method often fails in ALS with bulbar involvement, allegedly ...
    • Larynx during exercise: the unexplored bottleneck of the airways 

      Røksund, Ola Drange; Heimdal, John-Helge; Olofsson, Jan; Maat, Robert; Halvorsen, Thomas (Peer reviewed; Journal article, 2014-07-18)
      Exercise-induced shortness of breath is not uncommon in otherwise healthy young people. Based on the presenting symptoms alone, it is challenging to distinguish exercise-induced asthma (EIA) from exercise-induced obstruction ...
    • Long Waiting Times for Elective Hospital Care – Breaking the Vicious Circle by Abandoning Prioritisation 

      Sæther, Solbjørg Makalani Myrtveit; Heggestad, Torhild; Heimdal, John-Helge; Myrtveit, Magne (Peer reviewed; Journal article, 2019)
      Background: Policies assigning low-priority patients treatment delays for care, in order to make room for patients of higher priority arriving later, are common in secondary healthcare services today. Alternatively, each ...
    • Reliability of translaryngeal airway resistance measurements during maximal exercise 

      Fretheim-Kelly, Zoe; Engan, Mette; Clemm, Hege Synnøve Havstad; Andersen, Tiina Maarit; Heimdal, John-Helge; Strand, Eric; Halvorsen, Thomas; Røksund, Ola Drange; Vollsæter, Maria (Journal article; Peer reviewed, 2022)
      Objective Exercise-induced laryngeal obstruction is an important cause of exertional dyspnoea. The diagnosis rests on visual judgement of relative changes of the laryngeal inlet during continuous laryngoscopy exercise (CLE) ...
    • Severe exercise-induced laryngeal obstruction treated with supraglottoplasty 

      Sandnes, Astrid; Hilland, Magnus; Vollsæter, Maria; Andersen, Tiina Maarit; Engesæter, Ingvild Øvstebø; Sandvik, Lorentz; Heimdal, John-Helge; Halvorsen, Thomas; Eide, Geir Egil; Røksund, Ola Drange; Clemm, Hege Synnøve Havstad (Peer reviewed; Journal article, 2019-07-31)
      Introduction: Exercise induced laryngeal obstruction (EILO) is relatively common in adolescents, with symptoms often confused with exercise induced asthma. EILO often starts with medial or inward rotation of supraglottic ...
    • Stimulated monocyte IL-6 secretion predicts survival of patients with head and neck squamous cell carcinoma 

      Heimdal, John-Helge; Kross, Kenneth; Klementsen, Beate; Olofsson, Olaf; Aarstad, Hans Jørgen (Peer reviewed; Journal article, 2008-01-30)
      Background This study was performed in order to determine whether monocyte in vitro function is associated with presence, stage and prognosis of head and neck squamous cell carcinoma (HNSCC) disease. Methods Prospective ...
    • Vocal Cord Function During Recurrent Laryngeal Nerve Injury Assessed by Accelerometry and EMG 

      Dahle, Geir Olav; Setså, Erling Johan; Svendsen, Øyvind Sverre; Stangeland, Lodve; Heimdal, John-Helge; Henriksen, Bård; Husby, Paul; Brauckhoff, Katrin (Peer reviewed; Journal article, 2019-08-02)
      Objective Gradual impairment of nerve conduction is expected to be tightly associated with simultaneous gradual loss of vocal cord contractility, related to the fact that injured axons are connected to a defined number of ...