Browsing Bergen Open Research Archive by Author "Heldal, Einar"
Now showing items 1-7 of 7
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Building sustainable operational research capacity in Pakistan: starting with tuberculosis and expanding to other public health problems
Fatima, Razia; Yaqoob, Aashifa; Qadeer, Ejaz; Hinderaker, Sven Gudmund; Heldal, Einar; Zachariah, Rony; Harries, Anthony D.; Kumar, Ajay M.V. (Peer reviewed; Journal article, 2019)Background: For many years, operational research capacity has been a challenge and has remained a low priority for the health sector in Pakistan. Building research capacity for developing a critical mass of researchers in ... -
Extending contact screening within a 50-m radius of an index tuberculosis patient using Xpert MTB/RIF in urban Pakistan: Did it impact treatment outcomes?
Ul Haq, Mahboob; Hinderaker, Sven Gudmund; Fatima, Razia; Shewade, Hemant Deepak; Heldal, Einar; Latif, Abdullah; Kumar, Ajay M.V. (Journal article; Peer reviewed, 2021)Background Pakistan implemented initiatives to detect tuberculosis (TB) patients through extended contact screening (ECS); it improved case detection but treatment outcomes need assessment. Objectives To compare ... -
How many of persistent coughers have pulmonary tuberculosis? Populationbased cohort study in Ethiopia
Banti, Abiot Bezabeh; Datiko, Daniel Gemechu; Hinderaker, Sven Gudmund; Heldal, Einar; Dangisso, Mesay Hailu; Mitiku, Gebeyehu Assefa; White, Richard Aubrey; Askeland Winje, Brita (Journal article; Peer reviewed, 2022)Objective Many individuals with persistent cough and smear microscopy-negative sputum test for tuberculosis (TB) remain at risk of developing the disease. This study estimates the incidence of pulmonary TB (PTB) among ... -
Individual Variation in Adaptive Immune Responses and Risk of Hip Fracture-A NOREPOS Population-Based Cohort Study
Dahl, Jesper; Holvik, Kristin; Heldal, Einar; Grimnes, Guri; Hoff, Mari; Finnes, Trine; Apalset, Ellen Margrete; Meyer, Haakon E (Journal article; Peer reviewed, 2020)Immune‐mediated bone loss significantly impacts fracture risk in patients with autoimmune disease, but to what extent individual variations in immune responses affect fracture risk on a population level is unknown. To ... -
Prevalence and incidence of symptomatic pulmonary tuberculosis based on repeated population screening in a district in Ethiopia: a prospective cohort study
Banti, Abiot Bezabeh; Askeland Winje, Brita; Hinderaker, Sven Gudmund; Heldal, Einar; Abebe, Markos; Dangisso, Mesay Hailu; Datiko, Daniel Gemechu (Journal article; Peer reviewed, 2023)Objective In Ethiopia, one-third of the estimated tuberculosis cases are not detected or reported. Incidence estimates are inaccurate and rarely measured directly. Assessing the ‘real’ incidence under programme conditions ... -
Prevention of bronchial fistulas after pneumonectomies for selected cavitary drug resistant lung tuberculosis
Bazhenov, Alexander V.; Mariandyshev, Andrei O.; Hinderaker, Sven Gudmund; Heldal, Einar; Motus, Igor Ya.; Vasilyeva, Irina A. (Journal article; Peer reviewed, 2023)Background: The World Health Organization guidelines for management drug resistant tuberculosis include surgery as an additional method in selected cases. Pneumonectomies have higher risk of morbidity such as bronchial ... -
Strong tuberculin response after BCG vaccination is associated with low multiple sclerosis risk: a population-based cohort study
Nakken, Ola; Holmøy, Trygve; Stigum, Hein; Myhr, Kjell-Morten; Dahl, Jesper; Heldal, Einar; Meyer, Haakon Eduard (Journal article; Peer reviewed, 2022)Background: Multiple sclerosis (MS) is characterized by inflammatory lesions in the central nervous system involving pro-inflammatory T-cells. Immune dysregulation is well described in prevalent disease, but it is not known ...