Browsing Bergen Open Research Archive by Author "Helgeland, Lars"
Now showing items 1-9 of 9
-
Basosquamous Basal Cell Carcinoma with Bone Marrow Metastasis
Thunestvedt, Lise Mayrin Økland; Helgeland, Lars; Bachmann, Ingeborg Margrethe; Karlsdottir, Åsa; Haslerud, Torjan Magne; Reikvam, Håkon (Journal article; Peer reviewed, 2022-03-23)Basal cell carcinoma (BCC) is the most common cancer in Caucasians. It is slow growing and rarely metastasizes. If left untreated over time, invasive growth can occur. We present a patient case with a primary BCC located ... -
Concomitant Hemophagocytic Lymphohistiocytosis and Cytomegalovirus Disease: A Case Based Systemic Review
Rolsdorph, Linn; Mosevoll, Knut Anders; Helgeland, Lars; Reikvam, Håkon (Journal article; Peer reviewed, 2022)Background: Hemophagocytic lymphohistiocytosis (HLH) is an immune mediated life-threatening condition. It is driven by an overactivation of the immune system and causes inflammatory tissue damage potentially leading to ... -
IGHV gene usage and mutational status in follicular lymphoma: Correlations with prognosis and patient age
Berget, Ellen; Molven, Anders; Løkeland, Turid; Helgeland, Lars; Vintermyr, Olav Karsten (Peer reviewed; Journal article, 2015-07)Follicular lymphoma (FL) is a heterogeneous disease with some patients developing progressively or transformed disease early, whereas others follow an indolent clinical course. We evaluated the prognostic value of ... -
Microvascular proliferation is associated with aggressive tumour features and reduced survival in lung adenocarcinoma
Ramnefjell, Maria; Aamelfot, Christina; Aziz, Sura Mohammed; Helgeland, Lars; Akslen, Lars A. (Peer reviewed; Journal article, 2017-10)Despite new treatment options in lung cancer, there is still a need for better biomarkers to assist in therapy decisions. Angiogenesis has been associated with tumour growth and dissemination, and the vascular proliferation ... -
No Protection against DSS-induced Colitis by Short-term Pretreatment with Seal or Fish Oils in Rats
Arslan, Gülen; Erichsen, Kari; Milde, Anne Marita; Helgeland, Lars; Bjørkkjær, Tormod; Frøyland, Livar; Berstad, Arnold (Peer reviewed; Journal article, 2007-04-30)Background: Omega-3 (n-3) polyunsaturated fatty acids (PUFAs) have modulating effects in several chronic infl ammatory conditions. The aim of the present study was to test whether prior short-term dietary supplementation ... -
Novel Insights into the Pathogenesis of Human Post-Primary Tuberculosis from Archival Material of the Pre-Antibiotic Era, 1931–1947
Riaz, Syeda Mariam; Hanevik, Kurt; Helgeland, Lars; Sviland, Lisbet; Hunter, Robert L.; Mustafa, Tehmina (Journal article; Peer reviewed, 2023)Objectives: Primary and post-primary tuberculosis (TB) are distinct entities. The aim of this study was to study the histopathology of primary and post-primary TB by using the unique human autopsy material from the ... -
Prognostic value of bone marrow involvement by clonal immunoglobulin gene rearrangements in follicular lymphoma
Berget, Ellen; Helgeland, Lars; Liseth, Knut; Løkeland, Turid; Molven, Anders; Vintermyr, Olav Karsten (Peer reviewed; Journal article, 2014-09-18)Aims: We aimed to evaluate the prognostic value of routine use of PCR amplification of immunoglobulin gene rearrangements in bone marrow (BM) staging in patients with follicular lymphoma (FL). Methods: Clonal rearrangements ... -
Tumor HPV status, level of regulatory T cells and macrophage infiltration predict up to 20-year non-disease-specific survival in oropharynx squamous cell carcinoma patients
Haave, Hilde; Ljøkjel, Borghild; Lybak, Helene; Moe, Svein Erik Emblem; Berge, Jan Erik; Vintermyr, Olav Karsten; Helgeland, Lars; Aarstad, Hans Jørgen (Journal article; Peer reviewed, 2022)Oropharynx squamous cell carcinoma (OPSCC) is of special interest because human papilloma virus (HPV) and/or smoking cause this disease. Influxes of inflammatory cells into such tumors are known to vary with prognoses. ... -
Tumor infiltration levels of CD3, Foxp3 (+) lymphocytes and CD68 macrophages at diagnosis predict 5-year disease-specific survival in patients with oropharynx squamous cell carcinoma
Ljøkjel, Borghild; Haave, Hilde; Lybak, Stein; Vintermyr, Olav Karsten; Helgeland, Lars; Aarstad, Hans Jørgen (Journal article; Peer reviewed, 2022)Head and neck cancer (HNC) is the sixth most common cancer worldwide. Oropharyngeal (OP) cancers are of special interest because of possible underlying HPV infection which is tied to prognosis. Influxes of inflammatory ...