Blar i Bergen Open Research Archive på forfatter "Henklein, Peter"

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    • Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly 

      Votteler, Jörg; Neumann, Liane; Hahn, Sabine; Hahn, Friedrich; Rauch, Pia; Schmidt, Kerstin; Studtrucker, Nicole; Solbak, Sara Marie Øie; Fossen, Torgils; Henklein, Peter; Ott, David E.; Holland, Gudrun; Bannert, Norbert; Schubert, Ulrich (Peer reviewed; Journal article, 2011-02-16)
      Background: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic ...

    • The Host-Pathogen interaction of Human Cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains 

      Solbak, Sara Marie Øie; Wray, Victor; Horvli, Ole; Raae, Arnt Johan; Flydal, Marte Innselset; Henklein, Petra; Henklein, Peter; Nimtz, Manfred; Schubert, Ulrich; Fossen, Torgils (Peer reviewed; Journal article, 2011-12-20)
      Background: Cyclophilin A (CypA) represents a potential key molecule in future antiretroviral therapy since inhibition of CypA suppresses human immunodeficiency virus type 1 (HIV-1) replication. CypA interacts with the ...

    • The intriguing Cyclophilin A-HIV-1 Vpr interaction: prolyl cis/trans isomerisation catalysis and specific binding 

      Solbak, Sara Marie Øie; Reksten, Tove Ragna; Wray, Victor; Bruns, Karsten; Horvli, Ole; Raae, Arnt Johan; Henklein, Petra; Henklein, Peter; Röder, Rene; Mitzner, David; Schubert, Ulrich; Fossen, Torgils (Peer reviewed; Journal article, 2010-10-04)
      Background: Cyclophilin A (CypA) represents a potential target for antiretroviral therapy since inhibition of CypA suppresses human immunodeficiency virus type 1 (HIV-1) replication, although the mechanism through which ...