Browsing Bergen Open Research Archive by Author "Hertel, Jens Kristoffer"
Now showing items 1-12 of 12
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Association of body mass index with risk of acute myocardial infarction and mortality in Norwegian male and female patients with suspected stable angina pectoris: a prospective cohort study
Borgeraas, Heidi; Hertel, Jens Kristoffer; Svingen, Gard Frodahl Tveitevåg; Seifert, Reinhard; Pedersen, Eva Kristine Ringdal; Schartum-Hansen, Hall; Hjelmesæth, Jøran; Nygård, Ottar (Peer reviewed; Journal article, 2014-05-21)Background: A number of previous studies have suggested that overweight or obese patients with coronary artery disease (CAD) may have lower morbidity and mortality than their leaner counterparts. Few studies have addressed ... -
Cardiometabolic risk factors differ among adolescents with obesity in three European countries - a cross sectional study
Benestad, Beate; Juliusson, Petur Benedikt; Siegfried, Wolfgang; Lekhal, Samira; Småstuen, Milada Cvancarova; Hertel, Jens Kristoffer; Agosti, Fiorenza; Marazzi, Nicoletta; Hjelmesæth, Jøran; Sartorio, Alessandro (Peer reviewed; Journal article, 2018-03)Aim: We aimed to compare modifiable cardiometabolic risk factors among treatment‐seeking adolescents with obesity in Italy, Germany and Norway. Methods: This retrospective, registry‐based, cross‐sectional cohort study ... -
The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey)
Helgeland, Øyvind; Hertel, Jens Kristoffer; Molven, Anders; Ræder, Helge; Platou, Carl Geoffrey Parrinder; Midthjell, Kristian; Hveem, Kristian; Nygård, Ottar; Njølstad, Pål R.; Johansson, Stefan (Peer reviewed; Journal article, 2015)Background. Two adjacent regions upstream CDKN2B on chromosome 9p21 have been associated with type 2 diabetes (T2D) and progression of cardiovascular disease (CVD).The precise location and number of risk variants have not ... -
Distinct T cell subsets in adipose tissue are associated with obesity
Haugstøyl, Martha Eimstad; Cornillet, Martin; Strand, Kristina; Stiglund, Natalie; Sun, Dan; Lawrence-Archer, Laurence; Hjellestad, Iren Drange; Sparrelid, Ernesto; Busch, Christian; Hjelmesæth, Jøran Sture; Hertel, Jens Kristoffer; Ponzetta, Andrea; Mellgren, Gunnar; Fernø, Johan; Björkström, Niklas K. (Journal article; Peer reviewed, 2022)Adipose tissue inflammation is a driving factor for the development of obesity-associated metabolic disturbances, and a role of adipose tissue T cells in initiating the pro-inflammatory signaling is emerging. However, data ... -
Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study)
Hertel, Jens Kristoffer; Johansson, Stefan; Ræder, Helge; Platou, Carl G. P.; Midthjell, Kristian; Hveem, Kristian; Molven, Anders; Njølstad, Pål Rasmus (Peer reviewed; Journal article, 2011-02-04)<b>Background:</b> Chronic hyperglycemia confers increased risk for long-term diabetes-associated complications and repeated hemoglobin A1c (HbA1c) measures are a widely used marker for glycemic control in diabetes treatment ... -
FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life: A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies
Hertel, Jens Kristoffer; Johansson, Stefan; Sonestedt, Emily; Jonsson, Anna; Lie, Rolv Terje; Platou, Carl G. P.; Nilsson, Peter M.; Rukh, Gull; Midthjell, Kristian; Hveem, Kristian; Melander, Olle; Groop, Leif; Lyssenko, Valeriya; Molven, Anders; Orho-Melander, Marju; Njølstad, Pål Rasmus (Journal article; Peer reviewed, 2011-05)OBJECTIVE—FTO is the most important polygene identified for obesity. We aimed to investigate whether a variant in FTO affects type 2 diabetes risk entirely through its effect on BMI and how FTO influences BMI across adult ... -
Gender-related differences in cardiometabolic risk factors and lifestyle behaviors in treatment-seeking adolescents with severe obesity
Barstad, Lisa Ha; Juliusson, Petur Benedikt; Johnson, Line Kristin; Hertel, Jens Kristoffer; Lekhal, Samira; Hjelmesæth, Jøran (Peer reviewed; Journal article, 2018-02-14)Background: Obesity during adolescence is associated with cardiovascular mortality in adulthood. The adverse obesity-related cardiometabolic risk profile is already observed in adolescence. We aimed to examine possible ... -
Genetic Risk Factors for Type 2 Diabetes and Related Traits
Hertel, Jens Kristoffer (Doctoral thesis, 2012-06-18) -
Laparoskopisk gastrisk bypassoperasjon versus livsstilsbehandling av unge med sykelig overvekt
Hjelmesæth, Jøran; Hertel, Jens Kristoffer; Holt, Ane Hjetland; Benestad, Beate; Seeberg, Lars Thomas; Lindberg, Morten; Halvorsen, Erling; Juliusson, Petur Benedikt; Sandbu, Rune; Lekhal, Samira (Journal article; Peer reviewed, 2020)BAKGRUNN Kunnskapsgrunnlaget om effekten av og komplikasjoner ved vektreduserende kirurgi hos ungdom er mangelfullt. Hovedformålet med 4XL-studien er å avklare om laparoskopisk Roux-en-Y gastrisk bypassoperasjon (LGBP) ... -
The liver-heart axis in patients with severe obesity: the association between liver fibrosis and chronic myocardial injury may be explained by shared risk factors of cardiovascular disease
Young, Juliet; Seeberg, Kathrine; Aakre, Kristin Moberg; Borgeraas, Heidi; Nordstrand, Njord; Wisløff, Torbjørn; Hjelmesæth, Jøran Sture; Omland, Torbjørn; Hertel, Jens Kristoffer (Journal article; Peer reviewed, 2024)Background: Severe obesity is associated with increased risk of non-alcoholic fatty liver disease and cardiovascular disease. We hypothesized that liver fibrosis as quantified by the Enhanced Liver Fibrosis (ELF) test would ... -
Single-centre, non-randomised clinical trial at a tertiary care centre to investigate 1-year changes in social experiences and biomarkers of well-being after bariatric surgery in individuals with severe obesity: protocol for the Bariatric Surgery and Social Experiences (BaSES) study
Pfabigan, Daniela M.; Hertel, Jens Kristoffer; Svanevik, Marius; Lindberg, Morten; Sailer, Uta; Hjelmesæth, Jøran Sture (Journal article; Peer reviewed, 2023)Introduction Obesity is linked to increased loneliness and less enjoyment of social interactions. While bariatric surgery is the most effective treatment targeting severe obesity, there is limited understanding as to whether ... -
Type 2 diabetes genes : present status and data from Norwegian studies
Hertel, Jens Kristoffer; Johansson, Stefan; Midthjell, Kristian; Nygård, Ottar; Njølstad, Pål Rasmus; Molven, Anders (Peer reviewed; Journal article, 2013)The worldwide rise in prevalence of type 2 diabetes has led to an intense search for the genetic risk factors of this disease. In type 2 diabetes and other complex disorders, multiple genetic and environmental factors, as ...