Blar i Bergen Open Research Archive på forfatter "Hestetun, Kjersti Elvestad"
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Mapping Proteome Changes in Microsatellite Stable, Recurrent Colon Cancer Reveals a Significant Immune System Signature
Berle, Magnus; Hestetun, Kjersti Elvestad; Vethe, Heidrun; Chera, Simona; Paulo, Joao A.; Dahl, Olav; Myklebust, Mette Pernille (Journal article; Peer reviewed, 2022)Background/Aim: Better stratification of the risk of relapse will help select the right patients for adjuvant treatment and improve targeted therapies for patients with colon cancer. Materials and Methods: To understand ... -
Predictive and prognostic markers in localized colon cancer : with emphasis on the biomarkers maspin, mismatch repair deficiency, CDX2, tumor grade, PD-L1, and tumor-infiltrating lymphocytes.
Hestetun, Kjersti Elvestad (Doctoral thesis, 2022-06-23)Colon cancer is one of the most common cancers worldwide. Predicting disease outcomes is challenging. Around 15-20% of patients will experience disease relapse. At the same time, a substantial fraction of patients will ... -
Stage-dependent prognostic shift in mismatch repair-deficient tumors: Assessing patient outcomes in stage II and III colon cancer
Hestetun, Kjersti Elvestad; Rosenlund, Nina Benedikte; Stanisavljevic, Luka; Dahl, Olav; Myklebust, Mette Pernille (Journal article; Peer reviewed, 2022)Introduction: Deficient mismatch repair (dMMR) or high microsatellite instability (MSI-H) is associated with an improved prognosis in colon cancer stage II but poor prognosis in stage IV colon cancer. The clinical significance ...