• The Association Between Exposure to Interferon-Beta During Pregnancy and Birth Measurements in Offspring of Women With Multiple Sclerosis 

      Burkill, Sarah; Vattulainen, Pia; Geissbuehler, Yvonne; Sabido Espin, Meritxell; Popescu, Catrinel; Suzart-Woischnik, Kiliana; Hillert, Jan; Artama, Miia; Verkkoniemi-Ahola, Auli; Myhr, Kjell-Morten; Cnattingius, Sven; Korhonen, Pasi; Montgomery, Scott; Bahmanyar, Shahram (Peer reviewed; Journal article, 2019-12-30)
      Background: Interferon-beta (IFN-beta) is a commonly used treatment for multiple sclerosis (MS). Current guidelines recommend cessation of treatment during pregnancy, however the results of past studies on the safety of ...
    • Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations 

      Olafsson, S.; Stridh, P.; Bos, Steffan Daniel; Ingason, Andrés; Euesden, J; Sulem, Patrick; Thorleifsson, Gudmar; Gustafsson, O; Geirsson, AJ; Jóhannesson, Ari J.; Thorsson, AV; Ludviksson, BR; Sigurgeirsson, Bardur; Jonasson, JG; Olafsson, E; Kristjansdottir, H; Olafsson, JH; Orvar, KB; Benediktsson, Rafn; Bjarnason, Ragnar; Kristjansdottir, Sjofn; Gislason, Thorarin; Valdimarsson, T; Mikaelsdottir, E; Sigurdsson, S; Jonsson, S; Rafnar, Thorunn; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Knudsen, Gun Peggy S.; Celius, Elisabeth Gulowsen; Myhr, Kjell-Morten; Gröndal, Gerdur; Steinsson, K; Valdimarsson, Helgi; Bjornsson, Sigurdur; Bjornsdottir, US; Bjornsson, Einar S.; Nilsson, B; Andreassen, Ole Andreas; Alfredsson, Lars; Hillert, Jan; Kockum, Ingrid; Másson, Gísli; Thorsteinssdottir, U; Gudbjartsson, Daniel F.; Stefansson, H; Hjaltason, H; Harbo, Hanne Flinstad; Olsson, T; Jonsdottir, I; Stefansson, K (Peer reviewed; Journal article, 2017)
      A meta-analysis of publicly available summary statistics on multiple sclerosis combined with three Nordic multiple sclerosis cohorts (21,079 cases, 371,198 controls) revealed seven sequence variants associating with multiple ...
    • Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort 

      Westerlind, Helga; Imrell, Kerstin; Ramanujam, Ryan; Myhr, Kjell-Morten; Celius, Elisabeth Gulowsen; Harbo, Hanne Flinstad; Oturai, Annette Bang; Hamsten, Anders; Alfredsson, Lars; Olsson, Tomas; Kockum, Ingrid; Koski, Timo; Hillert, Jan (Peer reviewed; Journal article, 2015)
      In an attempt to map chromosomal regions carrying rare gene variants contributing to the risk of multiple sclerosis (MS), we identified segments shared identical-by-descent (IBD) using the software BEAGLE 4.0’s refined IBD ...
    • Pregnancy outcomes after exposure to interferon beta: a register-based cohort study among women with MS in Finland and Sweden 

      Hakkarainen, Katja Marja; Juuti, Rosa; Burkill, Sarah; Geissbühler, Yvonne; Sabidó, Meritxell; Popescu, Catrinel; Suzart-Woischnik, Kiliana; Hillert, Jan; Artama, Miia; Verkkoniemi-Ahola, Auli; Myhr, Kjell-Morten; Mehtälä, Juha; Bahmanyar, Shahram; Montgomery, Scott; Korhonen, Pasi (Journal article; Peer reviewed, 2020)
      Background Our aim was to estimate and compare the prevalence of adverse pregnancy outcomes among pregnant women with multiple sclerosis (MS) exposed to interferon beta (IFNB) and among women with MS unexposed to any MS ...