• Agreement in reporting of asthma by parents or offspring - the RHINESSA generation study 

      Kuiper, Ingrid Nordeide; Svanes, Cecilie; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Dharmage, Shyamali C.; Holm, Mathias; Janson, Christer; Jõgi, Rain; Malinovschi, Andrei; Matheson, Melanie; Moratalla, Jesús Martínez; Gomez Real, Francisco; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Timm, Signe; Johannessen, Ane (Peer reviewed; Journal article, 2018-07-27)
      Background: Self-report questionnaires are commonly used in epidemiology, but may be susceptible to misclassification, especially if answers are given on behalf of others, e.g. children or parents. The aim was to determine ...
    • Association between abdominal and general obesity and respiratory symptoms, asthma and COPD. Results from the RHINE study 

      Kisiel, Marta A.; Arnfelt, Oscar; Lindberg, Eva; Jogi, Oscar; Malinovschi, Andrei; Johannessen, Ane; Benediktsdottir, Bryndis; Franklin, Karl; Holm, Mathias; Gomez Real, Francisco; Sigsgaard, Torben; Gislason, Thorarinn; Modig, Lars; Janson, Christer (Journal article; Peer reviewed, 2023)
      Introduction Previous studies on the association between abdominal and general obesity and respiratory disease have provided conflicting results. Aims and objectives We aimed to explore the associations of abdominal ...
    • Associations of preconception exposure to air pollution and greenness with offspring asthma and hay fever 

      Kuiper, Ingrid Nordeide; Markevych, Iana; Accordini, Simone; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Christensen, Jesper Heile; Forsberg, Bertil; Halvorsen, Thomas; Heinrich, Joachim; Hertel, Ole; Hoek, Gerard; Holm, Mathias; de Hoogh, Kees; Janson, Christer; Malinovschi, Anderi; Marcon, Alessandro; Sigsgaard, Torben; Svanes, Cecilie; Johannessen, Ane (Journal article; Peer reviewed, 2020)
      We investigated if greenness and air pollution exposure in parents’ childhood affect offspring asthma and hay fever, and if effects were mediated through parental asthma, pregnancy greenness/pollution exposure, and offspring ...
    • Asthma, allergic rhinitis and atopic dermatitis in association with home environment - The RHINE study 

      Wang, Juan; Janson, Christer; Malinovschi, Andrei; Holm, Mathias; Franklin, Karl A.; Modig, Lars; Johannessen, Ane; Schlünssen, Vivi; Gislason, Thorarinn; Jögi, Nils Oskar; Norbäck, Dan (Journal article; Peer reviewed, 2022)
      We studied home environment exposures in relation to asthma, allergic rhinitis and atopic dermatitis among offspring of participants (parents) in the Respiratory Health in Northern Europe (RHINE) study (age ≤ 30 y). Totally ...
    • Being overweight in childhood, puberty, or early adulthood: Changing asthma risk in the next generation? 

      Johannessen, Ane; Lønnebotn, Marianne; Calciano, Lucia; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Dharmage, Shyamali; Franklin, Karl A.; Gíslason, Þórarinn; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Jõgi, Rain; Kim, Jeong-Lim; Kirkeleit, Jorunn; Lodge, Caroline; Malinovschi, Andrei; Martinez-Moratalla, Jesus; Nilsen, Roy Miodini; Pereira-Vega, Antonio; Gomez Real, Francisco; Schlünssen, Vivi; Accordini, Simone; Svanes, Cecilie (Peer reviewed; Journal article, 2020-03)
      Background Overweight status and asthma have increased during the last decades. Being overweight is a known risk factor for asthma, but it is not known whether it might also increase asthma risk in the next generation. ...
    • Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study 

      Peralta, Gabriela P.; Marcon, Alessandro; Carsin, Anne-Elie; Abramson, Michael J.; Accordini, Simone; Amaral, André F.S.; Antó, Josep Maria; Bowatte, Gayan; Burney, Peter; Corsico, Angelo; Demoly, Pascal; Dharmage, Shyamali C.; Forsberg, Bertil; Fuertes, Elaine; Garcia-Larsen, Vanessa; Gislason, Thorarinn; Gullón, José-Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Janson, Christer; Jõgi, Rain; Johannessen, Ane; Leynaert, Bénédicte; Rovira, Jesús Martínez-Moratalla; Nowak, Dennis; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Sigsgaard, Torben; Siroux, Valérie; Squillacioti, Giulia; Urrutia, Isabel; Weyler, Joost; Zock, Jan-Paul; Garcia-Aymerich, Judith (Journal article; Peer reviewed, 2020)
      Background Previous studies have reported an association between weight increase and excess lung function decline in young adults followed for short periods. We aimed to estimate lung function trajectories during adulthood ...
    • Body silhouettes as a tool to reflect obesity in the past 

      Lønnebotn, Marianne; Svanes, Cecilie; Igland, Jannicke; Franklin, Karl A.; Accordini, Simone; Benediktsdóttir, Bryndís; Bentohuami, Hayat; Blanco, José Antonio Gullón; Bono, Roberto; Corsico, Angelo; Demoly, Pascal; Dharmage, Shyamali; Dorado Arenas, Sandra; Garcia, Judith; Heinrich, Joachim; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Leynaert, Bénédicte; Martinez-Moratalla, Jesús; Nowak, Dennis; Pin, Isabelle; Raherison-Semjen, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Dratva, Julia; Gomez Real, Francisco (Peer reviewed; Journal article, 2018-04-25)
      Life course data on obesity may enrich the quality of epidemiologic studies analysing health consequences of obesity. However, achieving such data may require substantial resources. We investigated the use of body silhouettes ...
    • Breathlessness across generations: results from the RHINESSA generation study 

      Ekström, Magnus; Johannessen, Ane; Abramson, Michael J.; Benediktsdóttir, Bryndís; Franklin, Karl A.; Gislason, Thorarinn; Real, Francisco Gomez; Holm, Mathias; Janson, Christer; Jogi, Rain; Lowe, Adrian J.; Malinovschi, Andrei; Martínez-Moratalla, Jesús; Oudin, Anna; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Svanes, Cecilie (Journal article; Peer reviewed, 2022)
      Background Breathlessness is a major cause of suffering and disability globally. The symptom relates to multiple factors including asthma and lung function, which are influenced by hereditary factors. No study has evaluated ...
    • Clinical remission of asthma and allergic rhinitis-in a longitudinal population study 

      Heldin, Johanna; Malinovschi, Andrei; Johannessen, Ane; Alving, Kjell; Holm, Mathias; Franklin, Karl A.; Forsberg, Bertil; Schlünssen, Vivi; Jögi, Rain; Gislason, Thorarinn; Benediktsdottir, Bryndis; Svanes, Cecilie; Janson, Christer (Journal article; Peer reviewed, 2022)
      Background: Although asthma and allergic rhinitis are chronic diseases, some patients experience periods of remission. Information on prognostic factors associated with the remission of asthma and allergic rhinitis is ...
    • Cohort profile: the multigeneration Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) cohort 

      Svanes, Cecilie; Johannessen, Ane; Bertelsen, Randi Jacobsen; Dharmage, Shyamali; Benediktsdottir, Bryndis; Bråbäck, Lennart; Gislason, Thorarinn; Holm, Mathias; Jögi, Oskar; Lodge, Caroline J; Malinovschi, Andrei; Martinez-Moratalla, Jesus; Oudin, Anna; Sánchez-Ramos, José Luis; Timm, Signe; Janson, Christer; Real, Francisco Gomez; Schlünssen, Vivi (Journal article; Peer reviewed, 2022)
      Purpose The Respiratory Health in Northern Europe, Spain and Australia (RHINESSA) cohort was established to (1) investigate how exposures before conception and in previous generations influence health and disease, ...
    • Dampness and mold at home and at work and onset of insomnia symptoms, snoring and excessive daytime sleepiness 

      Wang, Juan; Janson, Christer; Lindberg, Eva; Holm, Mathias; Gislason, Thorarinn; Benediktsdóttir, Bryndís; Johannessen, Ane; Schlünssen, Vivi; Jõgi, Rain; Franklin, Karl A.; Norbäck, Dan (Journal article; Peer reviewed, 2020)
      Aim To investigate whether exposure to dampness and mold at home and at work induce sleep disturbances and daytime sleepiness among adults. Materials and methods Associations between onset of sleep disturbances and ...
    • Describing the status of reproductive ageing simply and precisely: A reproductive ageing score based on three questions and validated with hormone levels 

      Triebner, Kai; Johannessen, Ane; Svanes, Cecilie; Leynaert, Bénédicte; Benediktsdóttir, Bryndís; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Lindberg, Eva; Moratalla, Jesús Martínez; Agirre, Nerea Muniozguren; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Hustad, Steinar; Rodríguez, Francisco J.; Gomez Real, Francisco (Journal article; Peer reviewed, 2020)
      Objective Most women live to experience menopause and will spend 4–8 years transitioning from fertile age to full menstrual stop. Biologically, reproductive ageing is a continuous process, but by convention, it is defined ...
    • Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS) 

      Triebner, Kai; Accordini, Simone; Calciano, Lucia; Johannessen, Ane; Benediktsdóttir, Bryndís; Bifulco, Ersilia; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Garcia-Aymerich, Judith; Gullón Blanco, José Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Debbie; Jõgi, Rain; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Svanes, Cecilie; Hustad, Simon Steinar; Leynaert, Bénédicte; Gomez Real, Francisco (Peer reviewed; Journal article, 2019)
      Objectives: Menopause involves hypoestrogenism, which is associated with numerous detrimental effects, including on respiratory health. Hormone replacement therapy (HRT) is often used to improve symptoms of menopause. The ...
    • Fathers’ preconception smoking and offspring DNA methylation 

      Kitaba, Negusse Tadesse; Knudsen, Gerd Toril Mørkve; Johannessen, Ane; Rezwan, Faisal I.; Malinovschi, Andrei; Oudin, Anna; Benediktsdottir, Bryndis; Martino, David; González, Francisco Javier Callejas; Gómez, Leopoldo Palacios; Holm, Mathias; Jögi, Nils Oskar; Dharmage, Shyamali C.; Skulstad, Svein Magne; Watkins, Sarah H.; Suderman, Matthew; Gomez Real, Francisco; Schlünssen, Vivi; Svanes, Cecilie; Holloway, John W. (Journal article; Peer reviewed, 2023)
      Background Experimental studies suggest that exposures may impact respiratory health across generations via epigenetic changes transmitted specifically through male germ cells. Studies in humans are, however, limited. ...
    • Female sex hormones and symptoms of obstructive sleep apnea in European women of a population-based cohort 

      Sigurðardóttir, Erla S.; Gislason, Thorarinn; Benediktsdottir, Bryndis; Hustad, Simon Steinar; Dadvand, Payam; Demoly, Pascal; Franklin, Karl A.; Heinrich, Joachim; Holm, Mathias; van der Plaat, Diana A.; Jõgi, Rain; Leynaert, Benedicte; Lindberg, Eva; Martinez-Moratalla, Jesus; De Aja, Leire Sainz; Pesce, Giancarlo; Pin, Isabelle; Raherison, Chantal; Pereira-Vega, Antonio; Real, Francisco Gomez; Triebner, Kai Philipp (Journal article; Peer reviewed, 2022)
      Background The prevalence of obstructive sleep apnea is higher in women after menopause. This is suggested to be a result of an altered sex hormone balance but has so far not been confirmed in a population-based ...
    • Indoor Airborne Microbiome and Endotoxin: Meteorological Events and Occupant Characteristics Are Important Determinants 

      Abouelhana, Hesham Amin Mohamed; Šantl-Temkiv, Tina; Cramer, Christine; Finster, Kai; Gomez Real, Francisco; Gislason, Thorarinn; Holm, Mathias; Janson, Christer; Jögi, Nils Oskar; Jogi, Rain; Malinovschi, Andrei; Marshall, Ian P. G.; Modig, Lars; Norbäck, Dan; Shigdel, Rajesh; Sigsgaard, Torben; Svanes, Cecilie; Thorarinsdottir, Hulda; Wouters, Inge M.; Schlünssen, Vivi; Bertelsen, Randi Jacobsen (Journal article; Peer reviewed, 2023)
      Airborne bacteria and endotoxin may affect asthma and allergies. However, there is limited understanding of the environmental determinants that influence them. This study investigated the airborne microbiomes in the homes ...
    • Inflammatory bowel disease and asthma. Results from the RHINE study 

      Kisiel, Marta A.; Sedvall, Martin; Malinovschi, Andrei; Franklin, Karl A.; Gislason, Thorarinn; Shlunssen, Vivi; Johansson, Ane; Modig, Lars; Jogi, Rain; Holm, Mathias; Svanes, Cecilie; Lindholdt, Louise; Carlson, Marie; Janson, Christer (Journal article; Peer reviewed, 2023)
      Background Asthma and inflammatory bowel disease (IBD) are common inflammatory diseases. The aim of this study was to investigate the associations of IBD with asthma and respiratory symptoms. Methods This study is ...
    • Lifelong exposure to air pollution and greenness in relation to asthma, rhinitis and lung function in adulthood 

      Kuiper, Ingrid Nordeide; Svanes, Cecilie; Markevych, Iana; Accordini, Simone; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Christensen, Jesper Heile; Forsberg, Bertil; Halvorsen, Thomas; Heinrich, Joachim; Hertel, Ole; Hoek, Gerard; Holm, Mathias; De Hoogh, Kees; Janson, Christer; Malinovschi, Andrei; Marcon, Alessandro; Nilsen, Roy Miodini; Sigsgaard, Torben; Johannessen, Ane (Journal article; Peer reviewed, 2021)
      Objectives To investigate if air pollution and greenness exposure from birth till adulthood affects adult asthma, rhinitis and lung function. Methods: We analysed data from 3428 participants (mean age 28) in the RHINESSA ...
    • Lifelong exposure to residential greenspace and the premenstrual syndrome: A population-based study of Northern European women 

      Triebner, Kai Philipp; Markevych, Iana; Bertelsen, Randi Jacobsen; Skottvoll, Bente Sved; Hustad, Simon Steinar; Forsberg, Bertil; Franklin, Karl A; Holm, Mathias; Lindberg, Eva; Heinrich, Joachim; Real, Francisco Gomez; Dadvand, Payam (Journal article; Peer reviewed, 2022)
      Background: The premenstrual syndrome (PMS) causes clinically relevant psychological and physical symptoms in up to 20% of women of reproductive age. To date, no studies have investigated the relationship between PMS and ...
    • Long-term exposure to low-level air pollution and greenness and mortality in Northern Europe. The Life-GAP project 

      Xu, Shanshan; Marcon, Alessandro; Bertelsen, Randi Jacobsen; Benediktsdottir, Bryndis; Brandt, Jørgen; Engemann, Kristine; Frohn, Lise Marie; Geels, Camilla; Gislason, Thorarinn; Heinrich, Joachim; Holm, Mathias; Janson, Christer; Markevych, Iana; Modig, Lars; Orru, Hans; Schlunssen, Vivi; Sigsgaard, Torben; Johannessen, Ane (Journal article; Peer reviewed, 2023)
      Background Air pollution has been linked to mortality, but there are few studies examining the association with different exposure time windows spanning across several decades. The evidence for the effects of green space ...