Browsing Bergen Open Research Archive by Author "Horn, Arild"
Now showing items 1-6 of 6
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Aspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial
Yaqub, Sheraz; Bjørnbeth, Bjørn Atle; Angelsen, Jon-Helge; Fristrup, Claus W.; Grønbech, Jon Erik; Hemmingsson, Oskar; Isaksson, Bengt; Juel, Ingebjørg Soterud; Larsen, Peter Nørgaard; Lindell, Gert; Mortensen, Frank V.; Mortensen, Kim Erlend; Rizell, Magnus; Sandström, Per; Sandvik, Oddvar Mathias; Sparrelid, Ernesto; Taflin, Helena; Taskén, Kjetil; Brudvik, Kristoffer Watten; Fretland, Åsmund Avdem; Horn, Arild; Kleive, Dyre; Labori, Knut Jørgen; Lassen, Kristoffer; Røsok, Bård Ingvald; Søreide, Jon Arne; Tholfsen, Tore; Villanger, Olaug; Waage, Anne (Journal article; Peer reviewed, 2021)Background Colorectal cancer is one the most common cancers in the western world with increasing incidence. Approximately 50% of the patients develop liver metastases. Resection of liver metastases is the treatment of ... -
Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases
Løes, Inger Marie; Immervoll, Heike; Sorbye, Halfdan; Angelsen, Jon-Helge; Horn, Arild; Knappskog, Stian; Lønning, Per Eystein (Peer reviewed; Journal article, 2016-04)We determined prognostic impact of KRAS, BRAF, PIK3CA and TP53 mutation status and mutation heterogeneity among 164 colorectal cancer (CRC) patients undergoing liver resections for metastatic disease. Mutation status was ... -
Performance comparison of three BRAF V600E detection methods in malignant melanoma and colorectal cancer specimen
Løes, Inger Marie; Immervoll, Heike; Angelsen, Jon-Helge; Horn, Arild; Geisler, Jürgen; Busch, Christian; Lønning, Per Eystein; Knappskog, Stian (Peer reviewed; Journal article, 2015-02)Personalized cancer care requires reliable biomarkers. While the BRAF V600E mutation is implemented in the clinic, no method for its detection has so far been established as reference. We aimed to perform a comprehensive ... -
Predictive factors for time to recurrence, treatment and post-recurrence survival in patients with initially resected colorectal liver metastases
Angelsen, Jon-Helge; Viste, Asgaut; Løes, Inger Marie; Eide, Geir Egil; Hoem, Dag; Sorbye, Halfdan; Horn, Arild (Peer reviewed; Journal article, 2015-12-03)Background: Despite progress in resection for colorectal liver metastases (CLM), the majority of patients experience recurrence. We aimed to evaluate factors influencing time to recurrence (TTR), treatment and post-recurrence ... -
Risk factors, complications and survival after upper abdominal surgery: A prospective cohort study
Aahlin, Eirik Kjus; Tranø, Geir; Johns, Neil; Horn, Arild; Søreide, Jon Arne; Fearon, Kenneth Christopher H.; Revhaug, Arthur; Lassen, Kristoffer (Peer reviewed; Journal article, 2015-07-07)Background: Preoperative weight loss and abnormal serum-albumin have traditionally been associated with reduced survival. More recently, a correlation between postoperative complications and reduced long-term survival has ... -
Surgery for colorectal liver metastases: the impact of resection margins on recurrence and overall survival
Angelsen, Jon-Helge; Horn, Arild; Eide, Geir Egil; Viste, Asgaut (Peer reviewed; Journal article, 2014-04-27)Background: Several reports have presented conflicting results regarding the association between resection margins (RMs) and outcome after surgery for colorectal liver metastases (CLM), especially in the era of modern ...