Blar i Bergen Open Research Archive på forfatter "Hugdahl, Kenneth Jan"
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Comparison of seven modelling algorithms for γ-aminobutyric acid–edited proton magnetic resonance spectroscopy
Craven, Alexander R.; Bhattacharyya, Pallab K.; Clarke, William T.; Dydak, Ulrike; Edden, Richard A.E.; Ersland, Lars; Mandal, Pravat K.; Mikkelsen, Mark; Murdoch, James B.; Near, Jamie; Rideaux, Reuben; Shukla, Deepika; Wang, Min; Wilson, Martin; Zöllner, Helge J.; Hugdahl, Kenneth Jan; Oeltzschner, Georg (Journal article; Peer reviewed, 2022)Edited MRS sequences are widely used for studying γ-aminobutyric acid (GABA) in the human brain. Several algorithms are available for modelling these data, deriving metabolite concentration estimates through peak fitting ... -
Correlates of Hallucinatory Experiences in the General Population: An International Multisite Replication Study
Moseley, Peter; Aleman, André; Allen, Paul; Bell, Vaughan; Bless, Josef Johann; Bortolon, Catherine; Cello, Matteo; Garrison, Jane; Hugdahl, Kenneth Jan; Kozáková, Eva; Larøi, Frank; Moffatt, Jamie; Say, Nicolas; Smailes, David; Suzuki, Mimi; Toh, Wei Lin; Woodward, Todd; Zaytseva, Yuliya; Rossell, Susan; Fernyhough, Charles (Journal article; Peer reviewed, 2021)Hallucinatory experiences can occur in both clinical and nonclinical groups. However, in previous studies of the general population, investigations of the cognitive mechanisms underlying hallucinatory experiences have ... -
Differential Effectiveness of Atypical Antipsychotics on Hallucinations: A Pragmatic Randomized Controlled Trial
Sinkeviciute, Igne; Hugdahl, Kenneth Jan; Bartz-Johannessen, Christoffer; Kroken, Rune Andreas; Løberg, Else-Marie; Kjelby, Eirik; Rettenbacher, maria; Joa, Inge; Reitan, Solveig Merete Klæbo; Alisauskiene, Renata; Fathian, Farivar; Johnsen, Erik (Journal article; Peer reviewed, 2021-07)Background Most studies investigating antipsychotic effectiveness report either total psychopathology or symptom cluster findings. Studies focusing on a separate symptom, such as hallucinations, a hallmark symptom in ... -
Estradiol driven change in hallucination proneness across the menstrual cycle as studied with a white noise paradigm
Hjelmervik, Helene; Hausmann, Markus; Bless, Josef J.; Harkestad, Nina; Hugdahl, Kenneth Jan; Laloyaux, Julien (Journal article; Peer reviewed, 2023)The estrogen hypothesis for schizophrenia suggests neuroprotective effects of estrogen for the development of the disorder and for symptom severity, including auditory hallucinations. Furthermore, estrogen has shown enhancing ... -
fMRI fluctuations within the language network are correlated with severity of hallucinatory symptoms in schizophrenia
Spironelli, Chiara; Marino, Marco; Mantini, Dante; Montalti, Riccardo; Craven, Alexander R.; Ersland, Lars; Angrilli, Alessandro; Hugdahl, Kenneth Jan (Journal article; Peer reviewed, 2023)Although schizophrenia (SZ) represents a complex multiform psychiatric disorder, one of its most striking symptoms are auditory verbal hallucinations (AVH). While the neurophysiological origin of this pervasive symptom has ... -
GABA, glutamatergic dynamics and BOLD contrast assessed concurrently using functional MRS during a cognitive task
Craven, Alexander R.; Dwyer, Gerard Eric; Ersland, Lars; Kazimierczak, Katarzyna Anna; Noeske, Ralph; Sandøy, Lydia Brunvoll; Johnsen, Erik; Hugdahl, Kenneth Jan (Journal article; Peer reviewed, 2023)A recurring issue in functional neuroimaging is how to link task-driven haemodynamic blood oxygen level dependent functional MRI (BOLD-fMRI) responses to underlying neurochemistry at the synaptic level. Glutamate and ... -
High levels of childhood trauma associated with changes in hippocampal functional activity and connectivity in young adults during novelty salience
Derome, Melodie; Machon, Sandra; Barker, Holly; Kozuharova, Petya; Orlov, Natasza; Morgenroth, Elenor; Hugdahl, Kenneth Jan; Allen, Paul (Journal article; Peer reviewed, 2023)Childhood trauma (CT) has been linked to increased risk for psychosis. Moreover, CT has been linked to psychosis phenotypes such as impaired cognitive and sensory functions involved in the detection of novel sensory stimuli. ... -
In the twilight zone: An epidemiological study of sleep-related hallucinations
Bless, Josef Johann; Hugdahl, Kenneth Jan; Kråkvik, Bodil; Vedul-Kjelsås, Einar; Kalhovde, Anne Martha; Grønli, Janne; Larøi, Frank (Journal article; Peer reviewed, 2021)Background Few studies have investigated hallucinations that occur at the onset/offset of sleep (called hypnagogic/hypnopompic hallucinations; HHHs), despite the fact that their prevalence in the general population is ... -
Modular-Level Functional Connectome Alterations in Individuals With Hallucinations Across the Psychosis Continuum
Schutte, Maya J. L.; Voppel, Alban; Collin, Guusje; Abramovic, Lucija; Boks, Marco P. M.; Cahn, Wiepke; van Haren, Neeltje E. M.; Hugdahl, Kenneth Jan; Koops, Sanne; Mandl, René C. W.; Sommer, Iris E. C. (Journal article; Peer reviewed, 2022)Functional connectome alterations, including modular network organization, have been related to the experience of hallucinations. It remains to be determined whether individuals with hallucinations across the psychosis ... -
Negative valence of hallucinatory voices as predictor of cortical glutamatergic metabolite levels in schizophrenia patients
Hjelmervik, Helene; Craven, Alexander R.; Johnsen, Erik; Kompus, Kristiina; Bless, Josef Johann; Sinkeviciute, Igne; Kroken, Rune Andreas; Løberg, Else-Marie; Ersland, Lars; Grüner, Eli Renate; Sommer, Iris E.; Hugdahl, Kenneth Jan (Journal article; Peer reviewed, 2021)Objectives Negative emotional valence of auditory verbal hallucinations (AVHs) in schizophrenia can be a source of distress and is considered a strong predictor of illness severity. Previous studies have found glutamate ... -
Pilot-RCT Finds No Evidence for Modulation of Neuronal Networks of Auditory Hallucinations by Transcranial Direct Current Stimulation
Marquardt, Lynn Anne; Craven, Alexander R.; Hugdahl, Kenneth Jan; Johnsen, Erik; Kroken, Rune Andreas; Kusztrits, Isabella; Specht, Karsten; Thomassen, Anne Synnøve; Weber, Sarah; Hirnstein, Marco (Journal article; Peer reviewed, 2022-10-12)Background: Transcranial direct current stimulation (tDCS) is used as treatment for auditory verbal hallucinations (AVH). The theory behind the treatment is that tDCS increases activity in prefrontal cognitive control ... -
Similarities and differences between intermittent and continuous resting-state fMRI
Beresniewicz, Justyna; Riemer, Frank; Kazimierczak, Katarzyna Anna; Ersland, Lars; Craven, Alexander R.; Hugdahl, Kenneth Jan; Grüner, Renate (Journal article; Peer reviewed, 2023)Introduction: Functional Magnetic Resonance Imaging (fMRI) block-design experiments typically include active ON-blocks with presentation of cognitive tasks which are contrasted with OFF- blocks with no tasks presented. ... -
Simultaneous Measurement of the BOLD Effect and Metabolic Changes in Response to Visual Stimulation Using the MEGA-PRESS Sequence at 3 T
Dwyer, Gerard Eric; Craven, Alexander R.; Beresniewicz, Justyna; Kazimierczak, Katarzyna Anna; Ersland, Lars; Hugdahl, Kenneth Jan; Grüner, Eli Renate (Journal article; Peer reviewed, 2021)The blood oxygen level dependent (BOLD) effect that provides the contrast in functional magnetic resonance imaging (fMRI) has been demonstrated to affect the linewidth of spectral peaks as measured with magnetic resonance ... -
Transcranial direct current stimulation (tDCS) enhances internal source monitoring abilities in healthy participants
Kusztrits, Isabella; Marquardt, Lynn Anne; Hugdahl, Kenneth Jan; Hirnstein, Marco (Journal article; Peer reviewed, 2021-09-16)Source monitoring refers to the ability to identify the origin of a memory, for example, whether you remember saying something or thinking about it, and confusions of these sources have been associated with the experience ...