Browsing Bergen Open Research Archive by Author "Hustad, Simon Steinar"

Now showing items 1-9 of 9

    • Association of CYP2D6 genotype and tamoxifen metabolites with breast cancer recurrence in a low-dose trial 

      DeCensi, Andrea; Johansson, Harriet; Helland, Thomas; Puntoni, Matteo; Macis, Debora; Aristarco, Valentina; Caviglia, Silvia; Webber, Tania Buttiron; Briata, Irene Maria; D’Amico, Mauro; Serrano, Davide; Guerrieri-Gonzaga, Aliana; Bifulco, Ersilia; Hustad, Simon Steinar; Søiland, Håvard; Boni, Luca; Bonanni, Bernardo; Mellgren, Gunnar (Journal article; Peer reviewed, 2021)
      Low-dose tamoxifen halves recurrence in non-invasive breast cancer without significant adverse events. Some adjuvant trials with tamoxifen 20 mg/day had shown an association between low endoxifen levels (9–16 nM) and ...

    • Effects of estradiol- and ethinylestradiol-based contraceptives on adrenal steroids: A randomized trial 

      Kangasniemi, Marika H; Arffman, Riikka K; Haverinen, Annina; Luiro, Kaisu; Hustad, Simon Steinar; Heikinheimo, Oskari; Tapanainen, Juha S; Piltonen, Terhi T (Journal article; Peer reviewed, 2022)
      Objectives: Ethinylestradiol (EE)-based combined oral contraceptives (COC) affect adrenal function by altering steroid and corticosteroid-binding globulin (CBG) synthesis that may contribute to adverse effects related to ...

    • Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS) 

      Triebner, Kai; Accordini, Simone; Calciano, Lucia; Johannessen, Ane; Benediktsdóttir, Bryndís; Bifulco, Ersilia; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Garcia-Aymerich, Judith; Gullón Blanco, José Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Debbie; Jõgi, Rain; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Svanes, Cecilie; Hustad, Simon Steinar; Leynaert, Bénédicte; Gomez Real, Francisco (Peer reviewed; Journal article, 2019)
      Objectives: Menopause involves hypoestrogenism, which is associated with numerous detrimental effects, including on respiratory health. Hormone replacement therapy (HRT) is often used to improve symptoms of menopause. The ...

    • Female sex hormones and symptoms of obstructive sleep apnea in European women of a population-based cohort 

      Sigurðardóttir, Erla S.; Gislason, Thorarinn; Benediktsdottir, Bryndis; Hustad, Simon Steinar; Dadvand, Payam; Demoly, Pascal; Franklin, Karl A.; Heinrich, Joachim; Holm, Mathias; van der Plaat, Diana A.; Jõgi, Rain; Leynaert, Benedicte; Lindberg, Eva; Martinez-Moratalla, Jesus; De Aja, Leire Sainz; Pesce, Giancarlo; Pin, Isabelle; Raherison, Chantal; Pereira-Vega, Antonio; Real, Francisco Gomez; Triebner, Kai Philipp (Journal article; Peer reviewed, 2022)
      Background The prevalence of obstructive sleep apnea is higher in women after menopause. This is suggested to be a result of an altered sex hormone balance but has so far not been confirmed in a population-based ...

    • Lifelong exposure to residential greenspace and the premenstrual syndrome: A population-based study of Northern European women 

      Triebner, Kai Philipp; Markevych, Iana; Bertelsen, Randi Jacobsen; Skottvoll, Bente Sved; Hustad, Simon Steinar; Forsberg, Bertil; Franklin, Karl A; Holm, Mathias; Lindberg, Eva; Heinrich, Joachim; Real, Francisco Gomez; Dadvand, Payam (Journal article; Peer reviewed, 2022)
      Background: The premenstrual syndrome (PMS) causes clinically relevant psychological and physical symptoms in up to 20% of women of reproductive age. To date, no studies have investigated the relationship between PMS and ...

    • Menopause as a predictor of new-onset asthma 

      Triebner, Kai; Johannessen, Ane; Puggini, Luca; Benediktsdottir, Bryndis; Bertelsen, Randi Jacobsen; Bifulco, Ersilia; Dharmage, Shyamali C.; Franklin, Karl A.; Gislason, Þórarinn; Holm, Mathias; Jarvis, Deborah; Leynaert, Bénédicte; Lindberg, Eva; Macsali, Ferenc; Malinovschi, Andrej; Norbäck, Dan; Omenaas, Ernst; Rodriguez, Francisco J; Saure, Eirunn Waatevik; Schlünssen, Vivi; Sigsgaard, Torben; Skorge, Trude Duelien; Wieslander, Gunilla; Zemp, Elisabeth; Svanes, Cecilie; Hustad, Simon Steinar; Gomez Real, Francisco (Peer reviewed; Journal article, 2015-01)
      Background: There is limited and conflicting evidence on the effect of menopause on asthma. Objectives: We sought to study whether the incidence of asthma and respiratory symptoms differ by menopausal status in a longitudinal ...

    • Multisteroid LC-MS/MS assay for glucocorticoids and androgens, and its application in Addison’s disease 

      Methlie, Paal; Hustad, Simon Steinar; Kellmann, Ralph; Almås, Bjørg; Moter-Erichsen, M; Husebye, ES; Løvås, Kristian (Peer reviewed; Journal article, 2013)
      Objective: Liquid chromatography–tandem mass spectrometry (LC–MS/MS) offers superior analytical specificity compared with immunoassays, but it is not available in many regions and hospitals due to expensive instrumentation ...

    • Residential surrounding greenspace and age at menopause: A 20-year European study (ECRHS) 

      Triebner, Kai; Markevych, Iana; Hustad, Simon Steinar; Benediktsdóttir, Bryndís; Forsberg, Bertil; Franklin, Karl A.; Gullón Blanco, José Antonio; Holm, Mathias; Jaquemin, Bénédicte; Jarvis, Debbie; Jõgi, Rain; Leynaert, Bénédicte; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Sánchez-Ramos, José Luis; Heinrich, Joachim; Gomez Real, Francisco; Dadvand, Payam (Peer reviewed; Journal article, 2019-08-19)
      Background Menopause is associated with a number of adverse health effects and its timing has been reported to be influenced by several lifestyle factors. Whether greenspace exposure is associated with age at menopause has ...

    • Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients 

      Helland, Thomas; Henne, Nina; Bifulco, Ersilia; Naume, Bjørn; Borgen, Elin; Kristensen, Vessela N.; Kvaløy, Jan Terje; Lash, Timothy L; Grenaker, Grethe Irene; van Schaik, RHN; Janssen, Emiel; Hustad, Simon Steinar; Lien, Ernst Asbjørn; Mellgren, Gunnar; Søiland, Håvard (Peer reviewed; Journal article, 2017-11-28)
      Background: Controversies exist as to whether the genetic polymorphisms of the enzymes responsible for the metabolism of tamoxifen can predict breast cancer outcome in patients using adjuvant tamoxifen. Direct measurement ...