Browsing Bergen Open Research Archive by Author "Iashchishyn, Igor A."

Now showing items 1-1 of 1

    • Cholesterol-containing lipid nanodiscs promote an α-synuclein binding mode that accelerates oligomerization 

      Jakubec, Martin; Bariås, Espen; Furse, Samuel Robert; Govasli Larsen, Morten Andreas; George, Vinnit; Turcu, Diana Cornelia; Iashchishyn, Igor A.; Morozova-Roche, Ludmilla A.; Halskau, Øyvind (Journal article; Peer reviewed, 2021)
      Dysregulation of the biosynthesis of cholesterol and other lipids has been implicated in many neurological diseases, including Parkinson's disease. Misfolding of α-synuclein (α-Syn), the main actor in Parkinson's disease, ...