Blar i Bergen Open Research Archive på forfatter "Iversen, Per Ole"
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Dendritic cells loaded with tumor antigens and a dual immunostimulatory and anti-IL-10 specific siRNA can prime T lymphocytes against leukemic cells
Iversen, Per Ole; Semaeva, Elvira; Sørensen, Dag R.; Wiig, Helge; Sioud, Mouldy (Peer reviewed; Journal article, 2009-12)Vaccines using dendritic cells (DCs) harboring leukemic antigens to stimulate T cells is a possible treatment of acute myeloid leukemia (AML). Limitations of breaking tolerance to leukemic cells and lack of specific ... -
Interstitial fluid: the overlooked component of the tumor microenvironment?
Wiig, Helge; Tenstad, Olav; Iversen, Per Ole; Kalluri, Raghu; Bjerkvig, Rolf (Peer reviewed; Journal article, 2010-07-23)Background: The interstitium, situated between the blood and lymph vessels and the cells, consists of a solid or matrix phase and a fluid phase, together constituting the tissue microenvironment. Here we focus on the ...