Blar i Bergen Open Research Archive på forfatter "Jørgensen, Hugo A."
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Anti-depressive effectiveness of olanzapine, quetiapine, risperidone and ziprasidone: a pragmatic, randomized trial
Kjelby, Eirik; Jørgensen, Hugo A.; Kroken, Rune A.; Løberg, Else-Marie; Johnsen, Erik (Peer reviewed; Journal article, 2011-08-31)Background: Efficacy studies indicate anti-depressive effects of at least some second generation antipsychotics (SGAs). The Bergen Psychosis Project (BPP) is a 24-month, pragmatic, industry-independent, randomized, head-tohead ... -
Cognitive changes in patients with acute phase psychosis - Effects of illicit drug use
Helle, Siri; Gjestad, Rolf; Johnsen, Erik; Kroken, Rune; Jørgensen, Hugo A.; Løberg, Else-Marie (Peer reviewed; Journal article, 2014-12)Illicit drug use may influence cognition in non-affective psychosis. Previous studies have shown better cognition in psychosis with illicit drug use as compared to psychosis only. Possibly, illicit drug using patients have ... -
Effectiveness of second generation antipsychotics: A systematic review of randomized trials
Johnsen, Erik; Jørgensen, Hugo A. (Peer reviewed; Journal article, 2008-04-25)Background Systematic reviews based on efficacy trials are inconclusive about which second generation antipsychotic drug (SGA) should be preferred in normal clinical practice, and studies with longer duration and more ... -
Effectiveness of second-generation antipsychotics: a naturalistic, randomized comparison of olanzapine, quetiapine, risperidone, and ziprasidone
Johnsen, Erik; Kroken, Rune A.; Wentzel-Larsen, Tore; Jørgensen, Hugo A. (Peer reviewed; Journal article, 2010-03-24)Background: No clear recommendations exist regarding which antipsychotic drug should be prescribed first for a patient suffering from psychosis. The primary aims of this naturalistic study were to assess the head-to-head ... -
Gene expression profiles in rat brain disclose CNS signature genes and regional patterns of functional specialisation
Stansberg, Christine; Vik-Mo, Audun O.; Holdhus, Rita; Breilid, Harald; Srebro, Boleslaw; Petersen, Kjell; Jørgensen, Hugo A.; Jonassen, Inge; Steen, Vidar Martin (Peer reviewed; Journal article, 2007-04-04)Background: The mammalian brain is divided into distinct regions with structural and neurophysiological differences. As a result, gene expression is likely to vary between regions in relation to their cellular composition ... -
Hallucinations in acutely admitted patients with psychosis, and effectiveness of risperidone, olanzapine, quetiapine, and ziprasidone: a pragmatic, randomized study
Johnsen, Erik; Sinkeviciute, Igne; Løberg, Else-Marie; Kroken, Rune A.; Hugdahl, Kenneth; Jørgensen, Hugo A. (Peer reviewed; Journal article, 2013-09-30)Background Hallucinations are prevalent in schizophrenia and related psychotic disorders and may have severe consequences for the affected patients. Antipsychotic drug trials that specifically address the anti-hallucinatory ... -
Treatment of schizophrenia with antipsychotics in Norwegian emergency wards, a cross-sectional national study
Kroken, Rune A.; Johnsen, Erik; Ruud, Torleif; Wentzel-Larsen, Tore; Jørgensen, Hugo A. (Peer reviewed; Journal article, 2009-05-16)Background: Surveys on prescription patterns for antipsychotics in the Scandinavian public health system are scarce despite the prevalent use of these drugs. The clinical differences between antipsychotic drugs are mainly ...