• Deficient phosphorylation of stat-1 in leukocytes identifies neutralizing antibodies in multiple sclerosis patients treated with interferon-beta 

      Gavasso, Sonia; Mosleth, Ellen Færgestad; Marøy, Tove Helene; Jørgensen, Katarina Mariann; Nakkestad, Hanne Linda; Gjertsen, Bjørn Tore; Myhr, Kjell-Morten; Vedeler, Christian A. (Peer reviewed; Journal article, 2014-02-19)
      Background: Anti interferon-beta (IFN-β) neutralizing antibodies (NAb) affect efficacy of treatment of multiple sclerosis patients, but exactly when the detrimental effects of NAbs offset therapeutic efficacy is debated. ...
    • Gel2DE - A software tool for correlation analysis of 2D gel electrophoresis data 

      Øye, Ola Kristoffer; Jørgensen, Katarina Mariann; Hjelle, Sigrun Margrethe; Sulen, André; Ulvang, Dag Magne; Gjertsen, Bjørn Tore (Peer reviewed; Journal article, 2013-07-06)
      Background: Two-dimensional gel electrophoresis (2DE) is a powerful technique for studying protein isoforms and their modifications. Existing commercial 2D image analysis tools rely on spot detection that limits analysis ...
    • Gene expression response in peripheral blood cells of petroleum workers exposed to sub-ppm benzene levels 

      Jørgensen, Katarina Mariann; Mosleth, Ellen Færgestad; Liland, Kristian Hovde; Hopf, Nancy Brenna; Holdhus, Rita; Stavrum, Anne-Kristin; Gjertsen, Bjørn Tore; Kirkeleit, Jorunn (Peer reviewed; Journal article, 2018-10-27)
      Altered gene expression in pathways relevant to leukaemogenesis, as well as reduced levels of circulating lymphocytes, have been reported in workers that were exposed to benzene concentrations below 1 ppm. In this study, ...
    • Investigating the frequency of triploid Atlantic salmon in wild Norwegian and Russian populations 

      Jørgensen, Katarina Mariann; Wennevik, Vidar; Sørvik, Anne Grete Eide; Unneland, Laila; Prusov, Sergey; Ayllon, Fernando; Glover, Kevin (Peer reviewed; Journal article, 2018-10-03)
      Background Fish may display variations in ploidy, including three sets of chromosomes, known as triploidy. A recent study revealed a frequency of ~ 2% spontaneous (i.e., non-intentional) triploidy in domesticated Atlantic ...
    • Judging a salmon by its spots: Environmental variation is the primary determinant of spot patterns in Salmo salar 

      Jørgensen, Katarina Mariann; Solberg, Monica Favnebøe; Besnier, Francois; Thorsen, Anders; Fjelldal, Per Gunnar; Skaala, Øystein; Malde, Ketil; Glover, Kevin (Peer reviewed; Journal article, 2018-04-12)
      Background. In fish, morphological colour changes occur from variations in pigment concentrations and in the morphology, density, and distribution of chromatophores in the skin. However, the underlying mechanisms remain ...