Blar i Bergen Open Research Archive på forfatter "Kørner, Hartwig"
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Accurate population-based model for individual prediction of colon cancer recurrence
Österman, Erik; Ekström, Joakim; Sjöblom, Tobias; Kørner, Hartwig; Myklebust, Tor Åge; Guren, Marianne; Glimelius, Bengt (Journal article; Peer reviewed, 2021)Background Prediction models are useful tools in the clinical management of colon cancer patients, particularly when estimating the recurrence rate and, thus, the need for adjuvant treatment. However, the most used models ... -
Anastomotic leak after surgery for colon cancer and effect on long‐term survival
Stormark, Kjartan; Krarup, Peter-Martin; Sjövall, Annika; Søreide, Kjetil; Kvaløy, Jan Terje; Nordholm-Carstensen, Andreas; Nedrebø, Bjørn Steinar Olden; Kørner, Hartwig (Journal article; Peer reviewed, 2020)Aim An anastomotic leak after surgery for colon cancer is a recognized complication but how it may adversely affect long‐term survival is less clear because data are scarce. The aim of the study was to investigate the ... -
Assessing the association of oxytocin augmentation with obstetric anal sphincter injury in nulliparous women: A population-based, case-control study
Rygh, Astrid; Skjeldestad, Finn Egil; Kørner, Hartwig; Eggebø, Torbjørn Moe (Peer reviewed; Journal article, 2014-07-24)Objective To assess the association of oxytocin augmentation with obstetric anal sphincter injury among nulliparous women. Design Population-based, case–control study. Setting Primary and secondary teaching hospital serving ... -
Colorectal cancer screening with repeated fecal immunochemical test versus sigmoidoscopy: baseline results from a randomized trial
Randel, Kristin Ranheim; Schult, Anna Lisa; Botteri, Edoardo; Hoff, Geir; Bretthauer, Michael; Ursin, Giske; Natvig, Erik; Berstad, Paula; Jørgensen, Anita; Sandvei, Per Kristian; Olsen, Marie Kristin Ek; Frigstad, Svein Oskar; Darre-Næss, Ole; Norvard, Espen R.; Bolstad, Nils; Kørner, Hartwig; Wibe, Arne; Wensaas, Knut-Arne; de Lange, Thomas; Holme, Øyvind (Journal article; Peer reviewed, 2021)Background and aims: The comparative effectiveness of sigmoidoscopy and fecal immunochemical testing (FIT) for colorectal cancer (CRC) screening is unknown. Methods: Individuals aged 50-74 years living in South-East Norway ... -
Enhanced Recovery After Colorectal Surgery (ERAS) in Elderly Patients Is Feasible and Achieves Similar Results as in Younger Patients
Forsmo, Håvard Mjørud; Erichsen, Christian; Rasdal, Anne; Kørner, Hartwig; Pfeffer, Frank (Peer reviewed; Journal article, 2017)Aim: Enhanced recovery after surgery (ERAS) is a multimodal approach that aims to optimize perioperative treatment. Whether elderly patients receiving colorectal surgery can adhere to and benefit from an ERAS approach is ... -
Experiences of recovery from colorectal cancer surgery after hospital discharge among the oldest old: a qualitative study
Eriksen, Kristina Sundt; Husebø, Sissel Iren Eikeland; Kørner, Hartwig; Lode, Kirsten (Journal article; Peer reviewed, 2021)Colorectal cancer affects a large number of people aged ≥80 years. Little is known about how they manage after discharge from hospital. The aim of this study was to explore the experiences of individuals aged ≥80 years ... -
Influence of microsatellite instability and KRAS and BRAF mutations on lymph node harvest in stage I–III colon cancers
Berg, Marianne; Guriby, Marianne; Nordgård, Oddmund; Nedrebø, Bjørn Steinar Olden; Ahlquist, Terje Cruickshank; Smaaland, Rune; Oltedal, Satu; Søreide, Jon Arne; Kørner, Hartwig; Lothe, Ragnhild A.; Søreide, Kjetil (Peer reviewed; Journal article, 2013)Lymph node (LN) harvest is influenced by several factors, including tumor genetics. Microsatellite instability (MSI) is associated with improved node harvest, but the association to other genetic factors is largely unknown. ... -
Long-term follow-up and survivorship after completing systematic surveillance in stage I–III colorectal cancer: who is still at risk?
Veen, Torhild; Stormark, Kjartan; Nedrebø, Bjørn Steinar Olden; Berg, Marianne; Søreide, Jon Arne; Kørner, Hartwig; Søreide, Kjetil (Peer reviewed; Journal article, 2015-09)Purpose: In patients with a high life expectancy at the time of surgery for colorectal cancer (CRC), the long-term outcome may be influenced by factors other than their cancer. We aimed to investigate the long-term outcome ... -
Lower conversion rate with robotic assisted rectal resections compared with conventional laparoscopy; a national cohort study
Myrseth, Elisabeth; Nymo, Linn Såve; Gjessing, Petter Fosse; Kørner, Hartwig; Kvaløy, Jan Terje; Norderval, Stig (Journal article; Peer reviewed, 2021)Background Conversion from laparoscopic to open access colorectal surgery is associated with a poorer postoperative outcome. The aim of this study was to assess conversion rates and outcomes after standard laparoscopic ... -
Molecular subtypes in stage II-III colon cancer defined by genomic instability: Early recurrence-risk associated with a high copy-number variation and loss of RUNX3 and CDKN2A
Berg, Marianne; Nordgård, Oddmund; Kørner, Hartwig; Oltedal, Satu; Smaaland, Rune; Søreide, Jon Arne; Søreide, Kjetil (Peer reviewed; Journal article, 2015-04-16)Objective: We sought to investigate various molecular subtypes defined by genomic instability that may be related to early death and recurrence in colon cancer. Methods: We sought to investigate various molecular subtypes ... -
One-year excess mortality and treatment in surgically treated patients with colorectal cancer: A EURECCA European comparison
Bahadoer, Renu R.; Bastiaannet, Esther; Claassen, Yvette H.M.; van der Mark, Marianne; van Eycken, Elizabeth; Verbeeck, Julie; Guren, Marianne; Kørner, Hartwig; Martling, Anna; Johansson, Robert; van de Velde, Cornelis J.H.; Dekker, Jan Willem T. (Journal article; Peer reviewed, 2021)Background Mortality in the first postoperative year represents an accurate reflection of the perioperative risk after colorectal cancer surgery. This research compares one-year mortality after surgery divided into three ... -
Patient-reported outcomes in palliative gastrointestinal stenting: a Norwegian multicenter study
Larssen, Lene; Medhus, Asle W.; Hjermstad, Marianne J.; Kørner, Hartwig; Glomsaker, Tom Birger; Søberg, Taran; Gleditsch, Dagfinn; Hovde, Øistein; Nesbakken, Arild; Tholfsen, Jan K.; Skreden, Knut; Hauge, Truls (Peer reviewed; Journal article, 2011-04-13)Background The clinical effect of stent treatment has been evaluated by mainly physicians; only a limited number of prospective studies have used patient-reported outcomes for this purpose. The aim of this work was to study ... -
The power of empirical data; lessons from the clinical registry initiatives in Scandinavian cancer care
Nilbert, Mef; Thomsen, Linda Aagaard; Winther Jensen, Jens; Møller, Henrik; Borre, Michael; Widenlou Nordmark, Arvid; Lambe, Mats; Brändström, Helena; Kørner, Hartwig; Møller, Bjørn; Ursin, Giske (Journal article; Peer reviewed, 2020)Background In Scandinavia, there is a strong tradition for research and quality monitoring based on registry data. In Denmark, Norway and Sweden, 63 clinical registries collect data on disease characteristics, treatment ... -
Prognostic relevance of an epigenetic biomarker panel in sentinel lymph nodes from colon cancer patients
Lind, Guro Elisabeth; Guriby, Marianne; Ahlquist, Terje Cruickshank; Hussain, Israr; Jeanmougin, Marine; Søreide, Kjetil; Kørner, Hartwig; Lothe, Ragnhild A; Nordgård, Oddmund (Peer reviewed; Journal article, 2017-09-05)Background: Patients with early colorectal cancer (stages I–II) generally have a good prognosis, but a subgroup of 15–20% experiences relapse and eventually die of disease. Occult metastases have been suggested as a marker ...