Browsing Bergen Open Research Archive by Author "Kühl, Melf-Jakob"
Now showing items 1-8 of 8
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Addressing implementation uncertainty in postdischarge malaria chemoprevention : Determinants of adherence, cost-effectiveness, and the value of further research in Malawi and other malaria-endemic African countries
Kühl, Melf-Jakob (Doctoral thesis, 2023-11-08)Bakgrunn: Malaria fortsetter å være en ledende årsak til dødsfall og dødelighet for barn som bor i malaria-endemiske områder i Afrika sør for Sahara. Verdens helseorganisasjon (WHO) anbefaler chemoprevention av malaria for ... -
Adherence to community versus facility-based delivery of monthly malaria chemoprevention with dihydroartemisinin-piperaquine for the post-discharge management of severe anemia in Malawian children: A cluster randomized trial
Nkosi-Gondwe, Thandile; Robberstad, Bjarne; Mukaka, Mavuto; Idro, Richard; Opoka, Robert; Banda, Saidon; Kühl, Melf-Jakob; Ter Kuile, Feiko O.; Blomberg, Bjørn; Phiri, Kamija S. (Journal article; Peer reviewed, 2021-08-10)Background: The provision of post-discharge malaria chemoprevention (PMC) in children recently admitted with severe anemia reduces the risk of death and re-admissions in malaria endemic countries. The main objective of ... -
Are we overlooking alcohol use by younger children?
Skylstad, Vilde; Babirye, Juliet Ndimwibo; Kiguli, Juliet; Skar, Ane-Marthe Solheim; Kühl, Melf-Jakob; Nalugya, Joyce Sserunjogi; Engebretsen, Ingunn Marie Stadskleiv (Journal article; Peer reviewed, 2022)Alcohol use is a leading contributor to the burden of disease among youth. Early-onset use is associated with later life dependency, ill health and poor social functioning. Yet, research on and treatment opportunities for ... -
Child alcohol use disorder in Eastern Uganda: screening, diagnostics, risk factors and management of children drinking alcohol in Uganda (TREAT CAUD): a mixed-methods research protocol
Skylstad, Vilde; Aber, Harriet; Bakken, Victoria; Dierkes, Jutta; Iversen, Silje Akselberg; Kisaakye, Esther; Kühl, Melf-Jakob; Nalugya, Joyce; Rayamajhi, Divya; Sebuwufu, Deogratious; Skar, Ane-Marthe Solheim; Skokauskas, Norbert; Valeckaite, Neda; Wamani, Henry; Engebretsen, Ingunn Marie Stadskleiv; Babirye, Juliet Ndimwibo (Journal article; Peer reviewed, 2021)Background Following a finding of alcohol use among children aged 5–8 years old in Mbale, Uganda, this project investigates the magnitude of alcohol and substance use among children ged 6–13 years old and related household, ... -
A cluster randomised trial to evaluate the effectiveness of household alcohol-based hand rub for the prevention of sepsis, diarrhoea, and pneumonia in Ugandan infants (the BabyGel trial): a study protocol
Chebet, Martin; Mukunya, David; Burgoine, Kathy; Kühl, Melf-Jakob; Wang, Duolao; Medina-Lara, Antonieta; Faragher, Eric Brian; Odiit, Amos; Olupot-Olupot, Peter; Engebretsen, Ingunn Marie Stadskleiv; Waniaye, John Baptist; Wandabwa, Julius; Tylleskär, Thorkild; Weeks, Andrew (Journal article; Peer reviewed, 2023)Background Infections are one of the leading causes of death in the neonatal period. This trial aims to evaluate if the provision of alcohol-based hand rub (ABHR) to pregnant women for postnatal household use prevents ... -
Economic evaluation of postdischarge malaria chemoprevention in preschool children treated for severe anaemia in Malawi, Kenya, and Uganda: A cost-effectiveness analysis
Kühl, Melf-Jakob; Gondwe, Thandile; Dhabangi, Aggrey; Kwambai, Titus K.; Mori, Amani Thomas; Opoka, Robert; John, C. Chandy; Idro, Richard; ter Kuile, Feiko O.; Phiri, Kamija S.; Robberstad, Bjarne (Journal article; Peer reviewed, 2022)Background Children hospitalised with severe anaemia in malaria-endemic areas are at a high risk of dying or being readmitted within six months of discharge. A trial in Kenya and Uganda showed that three months of ... -
Predicting adherence to postdischarge malaria chemoprevention in Malawian pre-school children: A prognostic multivariable analysis
Kühl, Melf-Jakob; Nkosi-Gondwe, Thandile; Ter Kuile, Feiko O.; Phiri, Kamija S.; Pannu, Mehmajeet Kaur; Mukaka, Mavuto; Robberstad, Bjarne; Engebretsen, Ingunn Marie Stadskleiv (Journal article; Peer reviewed, 2023)Chemoprevention with antimalarials is a key strategy for malaria control in sub-Saharan Africa. Three months of postdischarge malaria chemoprevention (PDMC) reduces malaria-related mortality and morbidity in pre-school ... -
Projected health impact of post-discharge malaria chemoprevention among children with severe malarial anaemia in Africa
Okell, Lucy C.; Kwambai, Titus K.; Dhabangi, Aggrey; Khairallah, Carole; Nkosi-Gondwe, Thandile; Winskill, Peter; Opoka, Robert; Mousa, Andria; Kühl, Melf-Jakob; Lucas, Tim C.D.; Challenger, Joseph D.; Idro, Richard; Weiss, Daniel J.; Cairns, Matthew; ter Kuile, Feiko O.; Phiri, Kamija; Robberstad, Bjarne; Mori, Amani Thomas (Journal article; Peer reviewed, 2023)Children recovering from severe malarial anaemia (SMA) remain at high risk of readmission and death after discharge from hospital. However, a recent trial found that post-discharge malaria chemoprevention (PDMC) with ...