• Cost effectiveness of adding budesonide/formoterol to tiotropium in COPD in four Nordic countries 

      Nielsen, Rune; Kankaanranta, Hannu; Bjermer, Leif; Lange, Peter; Arnetorp, Sofie; Hedegaard, Morten; Stenling, Anna; Mittmann, Nicole (Peer reviewed; Journal article, 2013-11)
      Objective: Assess the cost effectiveness of budesonide/formoterol (BUD/FORM) Turbuhaler®+tiotropium (TIO) HandiHaler® vs. placebo (PBO)+TIO in patients with chronic obstructive pulmonary disease (COPD) eligible for inhaled ...
    • Eosinophilic airway diseases: basic science, clinical manifestations and future challenges 

      Janson, Christer; Bjermer, Leif; Lehtimäki, Lauri; Kankaanranta, Hannu; Karjalainen, Jussi; Altraja, Alan; Yasinska, Valentyna; Aarli, Bernt Bøgvald; Rådinger, Madeleine; Hellgren, Johan; Lofdahl, Magnus; Howarth, Peter H; Porsbjerg, Celeste (Journal article; Peer reviewed, 2022)
      Eosinophils have a broad range of functions, both homeostatic and pathological, mediated through an array of cell surface receptors and specific secretory granules that promote interactions with their microenvironment. ...
    • Impact of the metabolic syndrome on cardiopulmonary morbidity and mortality in individuals with lung function impairment: a prospective cohort study of the Danish general population 

      Marott, Jacob Louis; Ingebrigtsen, Truls Sylvan; Çolak, Yunus; Kankaanranta, Hannu; Bakke, Per S.; Vestbo, Jørgen; Nordestgaard, Børge Grønne; Lange, Peter (Journal article; Peer reviewed, 2023)
      Background Whether the metabolic syndrome plays a role for the prognosis of individuals with lung function impairment (preserved ratio impaired spirometry (PRISm) or airflow limitation) is unclear. We hypothesised that ...
    • Multidisciplinary approaches to identifying and managing global airways disease: Expert recommendations based on qualitative discussions 

      Backer, Vibeke; Cardell, Lars Olaf; Lehtimäki, Lauri; Toppila-Salmi, Sanna K.; Bjermer, Leif; Reitsma, Sietze; Hellings, Peter Wim; Weinfeld, Dan; Aanæs, Kasper; Ulrik, Charlotte Suppli; Braunstahl, Gert-Jan; Aarli, Bernt Bøgvald; Danielsen, Arild; Kankaanranta, Hannu; Steinsvåg, Sverre Karmhus; Bachert, Claus (Journal article; Peer reviewed, 2023)
      Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma frequently co-exist and share pathologic features. Taking a “global” treatment approach benefits diagnosis and treatment of both, but care is often ...
    • Prevalence and management of severe asthma in the Nordic countries: findings from the NORDSTAR cohort 

      Hansen, Susanne; von Bülow, Anna; Sandin, Patrik; Ernstsson, Olivia; Janson, Christer; Lehtimäki, Lauri; Kankaanranta, Hannu; Ulrik, Charlotte; Aarli, Bernt Bøgvald; Wahl, Hanna Fues; Geale, Kirk; Tang, Sheila Tuyet; Wolf, Maija; Larsen, Tom; Altraja, Alan; Backmann, Helena; Kilpeläinen, Maritta; Viinanen, Arja; Ludviksdottir, Dora; Kauppi, Paula; Sverrild, Asger; Lehmann, Sverre; Backer, Vibeke; Yasinska, Valentyna; Skjold, Tina; Karjalainen, Jussi; Bossios, Apostolos; Porsbjerg, Celeste (Journal article; Peer reviewed, 2023)
      Background Real-life evidence on prevalence and management of severe asthma is limited. Nationwide population registries across the Nordic countries provide unique opportunities to describe prevalence and management patterns ...
    • Severe asthma trajectories in adults: findings from the NORDSTAR cohort 

      von Bülow, Anna; Hansen, Susanne; Sandin, Patrik; Ernstsson, Olivia; Janson, Christer; Lehtimäki, Lauri; Kankaanranta, Hannu; Ulrik, Charlotte; Aarli, Bernt Bøgvald; Geale, Kirk; Tang, Sheila Tuyet; Wolf, Maija; Backer, Vibeke; Hilberg, Ole; Altraja, Alan; Backman, Helena; Ludviksdottir, Dora; Björnsdottir, Unnur Steina; Kauppi, Paula; Sandström, Thomas; Sverrild, Asger; Yasinska, Valentyna; Kilpeläinen, Maritta; Dahlen, Barbro; Viinanen, Arja; Bjermer, Leif; Bossios, Apostolos; Porsbjerg, Celeste (Journal article; Peer reviewed, 2023)
      Background There is limited evidence on the pathways leading to severe asthma and we are presently unable to effectively predict the progression of the disease. We aimed to describe the longitudinal trajectories leading ...