• Epigenome-wide association of father's smoking with offspring DNA methylation: a hypothesis-generating study 

      Knudsen, Gerd Toril Mørkve; Rezwan, FI; Johannessen, Ane; Skulstad, Svein Magne; Bertelsen, Randi Jacobsen; Gomez Real, Francisco; Krauss-Etschmann, Susanne; Patil, Viswanath; Jarvis, Deborah; Arshad, SH; Holloway, John W; Svanes, Cecilie (Peer reviewed; Journal article, 2019)
      Epidemiological studies suggest that father’s smoking might influence their future children’s health, but few studies have addressed whether paternal line effects might be related to altered DNA methylation patterns in the ...
    • The Exposome Approach in Allergies and Lung Diseases: Is It Time to Define a Preconception Exposome? 

      López Cervantes, Juan Pablo; Lønnebotn, Marianne; Jögi, Nils Oskar; Calciano, Lucia; Kuiper, Ingrid Nordeide; Darby, Matthew G; Dharmage, Shyamali Chandrika; Real, Francisco Gomez; Hammer, Barbara; Bertelsen, Randi Jacobsen; Johannessen, Ane; Würtz, Anne Mette Lund; Knudsen, Gerd Toril Mørkve; Koplin, Jennifer; Pape, Kathrine; Skulstad, Svein Magne; Timm, Signe; Tjalvin, Gro; Krauss-Etschmann, Susanne; Accordini, Simone; Schlünssen, Vivi; Kirkeleit, Jorunn; Svanes, Cecilie (Journal article; Peer reviewed, 2021)
      Emerging research suggests environmental exposures before conception may adversely affect allergies and lung diseases in future generations. Most studies are limited as they have focused on single exposures, not considering ...
    • Fathers´ smoking in different time windows as related to offspring's epigenetic and phenotypic outcomes 

      Knudsen, Gerd Toril Mørkve (Doctoral thesis, 2023-02-17)
      Bakgrunn: Epidemiologiske studier tyder på at fars røyking, særlig hvis han begynner å røyke når han er svært ung (<15 år), kan påvirke overvekt og lungehelse hos fremtidige barn. Stoffene i tobakksrøyk kan føre til endring ...
    • Fathers’ preconception smoking and offspring DNA methylation 

      Kitaba, Negusse Tadesse; Knudsen, Gerd Toril Mørkve; Johannessen, Ane; Rezwan, Faisal I.; Malinovschi, Andrei; Oudin, Anna; Benediktsdottir, Bryndis; Martino, David; González, Francisco Javier Callejas; Gómez, Leopoldo Palacios; Holm, Mathias; Jögi, Nils Oskar; Dharmage, Shyamali C.; Skulstad, Svein Magne; Watkins, Sarah H.; Suderman, Matthew; Gomez Real, Francisco; Schlünssen, Vivi; Svanes, Cecilie; Holloway, John W. (Journal article; Peer reviewed, 2023)
      Background Experimental studies suggest that exposures may impact respiratory health across generations via epigenetic changes transmitted specifically through male germ cells. Studies in humans are, however, limited. ...
    • Parents’ smoking onset before conception as related to body mass index and fat mass in adult offspring: Findings from the RHINESSA generation study 

      Knudsen, Gerd Toril Mørkve; Dharmage, Shyamali C.; Janson, Christer; Abramson, Michael J.; Benediktsdóttir, Bryndís; Malinovschi, Andrei; Skulstad, Svein Magne; Bertelsen, Randi Jacobsen; Real, Francisco Gomez; Schlünssen, Vivi; Jögi, Nils Oskar; Sánchez-Ramos, José Luis; Holm, Mathias; Garcia-Aymerich, Judith; Forsberg, Bertil; Svanes, Cecilie; Johannessen, Ane (Journal article; Peer reviewed, 2020)
      Emerging evidence suggests that parents’ preconception exposures may influence offspring health. We aimed to investigate maternal and paternal smoking onset in specific time windows in relation to offspring body mass index ...
    • Preconceptional smoking alters spermatozoal miRNAs of murine fathers and affects offspring’s body weight 

      Hammer, Barbara; Kadalayil, Latha; Boateng, Eistine; Buschmann, Dominik; Rezwan, Faisal I.; Wolff, Martin; Reuter, Sebastian; Bartel, Sabine; Knudsen, Gerd Toril Mørkve; Svanes, Cecilie; Holloway, John W.; Krauss-Etschmann, Susanne (Journal article; Peer reviewed, 2021)
      Background Active smoking has been reported among 7% of teenagers worldwide, with ages ranging from 13 to 15 years. An epidemiological study suggested that preconceptional paternal smoking is associated with adolescent ...
    • Prevalence of Respiratory Symptoms and Chronic Obstructive Pulmonary Disease, and Reference Values for Lung Function Testing in Kinondoni District, Dar Es Salaam, Tanzania 

      Knudsen, Gerd Toril Mørkve (Master thesis, 2010-05-15)
      In the wake of socioeconomic development, changing demographics towards ageing populations and the expatiation of non-communicable diseases put additional strains and new challenges unto health services and disease management ...
    • Transgenerational and intergenerational epigenetic inheritance in allergic diseases 

      Knudsen, Gerd Toril Mørkve; Rezwan, Faisal I.; Jiang, Yu; Karmaus, Wilfried; Svanes, Cecilie; Holloway, John W. (Peer reviewed; Journal article, 2018-09)
      It has become clear that early life (including in utero exposures) is a key window of vulnerability during which environmental exposures can alter developmental trajectories and initiate allergic disease development. ...