• Birthweight and childhood cancer: Preliminary findings from the international childhood cancer cohort consortium (I4C) 

      Paltiel, Ora; Tikellis, Gabriella; Linet, Martha; Golding, Jean; Lemeshow, Stanley; Phillips, Gary; Lamb, Karen; Stoltenberg, Camilla; Håberg, Siri Eldevik; Strøm, Marin; Granstrøm, Charlotta; Northstone, Kate; Klebanoff, Mark; Ponsonby, Anne-Louise; Milne, Elizabeth; Pedersen, Marie; Kogevinas, Manolis; Ha, Eunhee; Dwyer, Terence (Peer reviewed; Journal article, 2015-07)
      Background: Evidence relating childhood cancer to high birthweight is derived primarily from registry and case–control studies. We aimed to investigate this association, exploring the potential modifying roles of age at ...
    • Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia 

      Witt, Stephanie H.; Streit, F; Jungkunz, M; Frank, J; Awasthi, S; Reinbold, CS; Treutlein, J; Degenhardt, F; Forstner, AJ; Heilmann-Heimbach, S; Dietl, L; Schwarze, CE; Schendel, D; Strohmaier, Jana; Abdellaoui, A; Adolfsson, Rolf; Air, TM; Akil, Huda; Alda, Martin; Alliey-Rodriguez, N; Andreassen, Ole Andreas; Babadjanova, Gulia; Bass, N; Bauer, M; Baune, Bernhard T.; Bellivier, Frank; Bergen, Sarah E; Bethell, A; Biernacka, Joanna M.; Blackwood, Douglas H.R.; Boks, Marco P; Boomsma, Dorret I.; Borglum, Anders D; Borrmann-Hassenbach, M; Brennan, P; Budde, M; Buttenschon, HN; Byrne, Enda M.; Cervantes, P; Clarke, TK; Craddock, N; Cruceanu, C; Curtis, David; Czerski, Piotr M.; Dannlowski, Udo; Davis, T; de Geus, Eco J C; Di Florio, A; Djurovic, Srdjan; Domenici, Enrico; Edenberg, Howard J; Etain, Bruno; Fischer, SB; Forty, L; Fraser, C; Frye, M; Fullerton, JM; Gershon, Elliot S.; Gieglin, I; Gordon, Scott D; Gordon-Smith, K; Grabe, Hans Jörgen; Green, EK; Greenwood, TA; Grigoroiu-Serbanescu, Maria; Guzman-Parra, J; Hall, L; Hamshere, Marian; Hauser, J; Hautzinger, Martin; Heilbronner, U; Herms, Stefan; Hitturlingappa, S; HOFFMANN, PAVEL; Holmans, P; Hottenga, Jouke Jan; Jamain, Stephane; Jones, I; Jones, L; Juréus, Anna; Kahn, René S; Kammerer-Ciernioch, Jutta; Kirov, George; Kittel-Schneider, Sarah; Kloiber, Stefan; Knott, SV; Kogevinas, Manolis; Landen, M; Leber, M; Leboyer, Marion; Li, Qingqin S.; Lissowska, Jolanta; Lucae, Susanne; Martin, NG; Mayoral-Cleries, F; McElroy, SL; McIntosh, Andrew M; McKay, James D; McQuilling, A; Medland, Sarah E; Middeldorp, Christel M.; Milaneschi, Y; Mitchell, Philip B; Montgomery, Grant W; Mors, O; Mühleisen, Thomas W.; Muller-Myshok, B; Myers, Richard M; Nievergelt, Caroline M.; Nurnberger, John I.; O'Donovan, Michael C; Loohuis, Loes M. Olde; Ophoff, R; Oruc, Liliana; Owen, Michael J; Paciga, SA; Penninx, Brenda W J H; Perry, A; Pfennig, Andrea; Potash, James B.; Preisig, Martin; Reif, A; Rivas, F; Rouleau, GA; Schofield, Peter R; Schulze, Thomas G; Schwarz, M; Scott, L; Sinnamon, GCB; Stahl, Eli A.; Strauss, J; Turecki, G; Van der Auwera, S; Vedder, Helmut; Vincent, John B; Willemsen, Gonneke; Witt, CC; Wray, Naomi R; Xi, HS; Tadic, A; Dahmen, Norbert; Schott, Björn H; Cichon, Sven; Nothen, Markus M; Ripke, Stephan; Mobascher, A; Rujescu, Dan; Lieb, K; Roepke, S; Schmal, Christine; Bohus, Martin; Rietschel, Marcella; Morken, Gunnar; Gade, K (Peer reviewed; Journal article, 2017-06-20)
      Borderline personality disorder (BOR) is determined by environmental and genetic factors, and characterized by affective instability and impulsivity, diagnostic symptoms also observed in manic phases of bipolar disorder ...
    • Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics 

      Beaumont, Robin N.; Warrington, Nicole M.; Cavadino, Alana; Tyrrell, Jessica; Nodzenski, Michael; Horikoshi, Momoko; Geller, Frank; Myhre, Ronny; Richmond, Rebecca C.; Paternoster, Lavinia; Bradfield, Jonathan P.; Kreiner-Møller, Eskil; Huikari, Ville; Metrustry, Sarah; Lunetta, Kathryn L.; Painter, Jodie N.; Hottenga, Jouke-Jan; Allard, Catherine; Barton, Sheila J.; Espinosa, Ana; Marsh, Julie A.; Potter, Catherine; Zhang, Ge; Ang, Wei; Berry, Diane J.; Bouchard, Luigi; Das, Shikta; Hakonarson, Hakon; Heikkinen, Jani; Helgeland, Øyvind; Hocher, Berthold; Hofman, Albert; Inskip, Hazel M.; Jones, Samuel E.; Kogevinas, Manolis; Lind, Penelope A.; Marullo, Letizia; Medland, Sarah E.; Murray, Anna; Murray, Jeffrey C.; Njølstad, Pål Rasmus; Nohr, Ellen A.; Reichetzeder, Christoph; Ring, Susan M.; Ruth, Katherine S.; Santa-Marina, Loreto; Scholtens, Denise M.; Sebert, Sylvain; Sengpiel, Verena; Tuke, Marcus A.; Vaudel, Marc; Weedon, Michael N.; Willemsen, Gonneke; Wood, Andrew R.; Yaghootkar, Hanieh; Muglia, Louis J.; Bartels, Meike; Relton, Caroline L.; Pennell, Craig E.; Chatzi, Leda; Estivill, Xavier; Holloway, John W.; Boomsma, Dorret I.; Montgomery, Grant W.; Murabito, Joanne M.; Spector, Tim D.; Power, Christine; Järvelin, Marjo-Riitta; Bisgaard, Hans; Grant, Struan F.A.; Sørensen, Thorkild I.A.; Jaddoe, Vincent W.; Jacobsson, Bo; Melbye, Mads; McCarthy, Mark I.; Hattersley, Andrew T.; Hayes, M. Geoffrey; Hivert, Marie-France; Frayling, Timothy M.; Felix, Janine F.; Hyppönen, Elina; Lowe, William L.; Evans, David M.; Lawlor, Debbie A.; Feenstra, Bjarke; Freathy, Rachel M. (Peer reviewed; Journal article, 2018-02)
      Genome-wide association studies of birth weight have focused on fetal genetics, whereas relatively little is known about the role of maternal genetic variation. We aimed to identify maternal genetic variants associated ...
    • Interaction between gas cooking and GSTM1 null genotype in bronchial responsiveness: Results from the European Community Respiratory Health Survey 

      Amaral, André F.S.; Ramasamy, Adaikalavan; Castro-Giner, Francesc; Minelli, Cosetta; Accordini, Simone; Sørheim, Inga Cecilie; Pin, Isabelle; Kogevinas, Manolis; Jõgi, Rain; Balding, David J.; Norbäck, Dan; Verlato, Guiseppe; Olivieri, Mario; Probst-Hensch, Nicole; Janson, Christer; Zock, Jan-Paul; Heinrich, Joachim; Jarvis, Deborah L. (Peer reviewed; Journal article, 2014)
      Background: Increased bronchial responsiveness is characteristic of asthma. Gas cooking, which is a major indoor source of the highly oxidant nitrogen dioxide, has been associated with respiratory symptoms and reduced lung ...
    • Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight 

      Küpers, Leanne K.; Monnereau, Claire; Sharp, Gemma C.; Yousefi, Paul; Salas, Lucas A.; Ghantous, Akram; Page, Christian Magnus; Reese, Sarah E.; Wilcox, Allen J.; Czamara, Darina; Starling, Anne P.; Novoloaca, Alexei; Lent, Samantha; Roy, Ritu; Hoyo, Cathrine; Breton, Carrie V.; Allard, Catherine; Just, Allan C.; Bakulski, Kelly M.; Holloway, John W.; Everson, Todd M.; Xu, Cheng-Jian; Huang, Rae-Chi; van der Plaat, Diana A.; Wielscher, Matthias; Merid, Simon Kebede; Ullemar, Vilhelmina; Rezwan, Faisal I.; Lahti, Jari; van Dongen, Jenny; Langie, Sabine A.S.; Richardson, Tom G.; Magnus, Maria Christine; Nohr, Ellen A.; Xu, Zongli; Duijts, Liesbeth; Zhao, Shanshan; Zhang, Weiming; Plusquin, Michelle; DeMeo, Dawn L.; Solomon, Olivia; Heimovaara, Joosje H.; Jima, Dereje D.; Gao, Lu; Bustamante, Mariona; Perron, Patrice; Wright, Robert O.; Hertz-Picciotto, Irva; Zhang, Hongmei; Karagas, Margaret R.; Gehring, Ulrike; Marsit, Carmen J.; Beilin, Lawrence J.; Vonk, Judith M.; Jarvelin, Marjo-Riitta; Bergström, Anna; Örtqvist, Anne K.; Ewart, Susan; Villa, Pia M.; Moore, Sophie E.; Willemsen, Gonneke; Standaert, Arnout R.L.; Håberg, Siri Eldevik; Sørensen, Thorkild I.A.; Taylor, Jack A.; Räikkönen, Katri; Yang, Ivana V.; Kechris, Katerina; Nawrot, Tim S.; Silver, Matt J.; Gong, Yun Yun; Richiardi, Lorenzo; Kogevinas, Manolis; Litonjua, Augusto A.; Eskenazi, Brenda; Huen, Karen; Mbarek, Hamdi; Maguire, Rachel L.; Dwyer, Terence; Vrijheid, Martine; Bouchard, Luigi; Baccarelli, Andrea A.; Croen, Lisa A.; Karmaus, Wilfried; Anderson, Denise; de Vries, Maaike; Sebert, Sylvain; Kere, Juha; Karlsson, Robert; Arshad, Syed Hasan; Hämäläinen, Esa; Routledge, Michael N.; Boomsma, Dorret I.; Feinberg, Andrew P.; Newschaffer, Craig J.; Govarts, Eva; Moisse, Matthieu; Fallin, M. Daniele; Melén, Erik; Prentice, Andrew M.; Kajantie, Eero; Almqvist, Catarina; Oken, Emily; Dabelea, Dana; Boezen, H. Marike; Melton, Philip E.; Wright, Rosalind J.; Koppelman, Gerard H.; Trevisi, Letizia; Hivert, Marie-France; Sunyer, Jordi; Munthe-Kaas, Monica Cheng; Murphy, Susan K.; Corpeleijn, Eva; Wiemels, Joseph L.; Holland, Nina; Herceg, Zdenko; Binder, Elisabeth B.; Davey Smith, George; Jaddoe, Vincent V.W.; Lie, Rolv T.; Nystad, Wenche; London, Stephanie J.; Lawlor, Debbie A.; Relton, Caroline L.; Snieder, Harold; Felix, Janine F. (Peer reviewed; Journal article, 2019-04-23)
      Birthweight is associated with health outcomes across the life course, DNA methylation may be an underlying mechanism. In this meta-analysis of epigenome-wide association studies of 8,825 neonates from 24 birth cohorts in ...