• Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice 

      Ruskamo, Salla; Krokengen, Oda Caspara; Kowal, Julia; Nieminen, Tuomo; Lehtimäki, Mari; Raasakka, Arne; Dandey, Venkata P; Vattulainen, Ilpo; Stahlberg, Henning; Kursula, Petri (Journal article; Peer reviewed, 2020)
      Myelin protein P2 is a peripheral membrane protein of the fatty acid–binding protein family that functions in the formation and maintenance of the peripheral nerve myelin sheath. Several P2 gene mutations cause human ...
    • Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line 

      Raasakka, Arne; Ruskamo, Salla; Kowal, Julia; Barker, Robert; Baumann, Anne; Martel, Anne; Tuusa, Jussi; Myllykoski, Matti; Bürck, Jochen; Ulrich, Anne S.; Stahlberg, Henning; Kursula, Petri (Peer reviewed; Journal article, 2017-07-10)
      Compact myelin comprises most of the dry weight of myelin, and its insulative nature is the basis for saltatory conduction of nerve impulses. The major dense line (MDL) is a 3-nm compartment between two cytoplasmic leaflets ...
    • Molecular structure and function of myelin protein P0 in membrane stacking 

      Raasakka, Arne; Ruskamo, Salla; Kowal, Julia; Han, Huijong; Baumann, Anne; Myllykoski, Matti; Fasano, Anna; Rossano, Rocco; Riccio, Paolo; Bürck, Jochen; Ulrich, Anne S.; Stahlberg, Henning; Kursula, Petri (Peer reviewed; Journal article, 2019)
      Compact myelin forms the basis of nerve insulation essential for higher vertebrates. Dozens of myelin membrane bilayers undergo tight stacking, and in the peripheral nervous system, this is partially enabled by myelin ...