• Development of selective ssDNA micro-probe for PD1 detection as a novel strategy for cancer imaging 

      Malicki, Stanisław; Czarna, Anna; Żyła, Edyta; Pucelik, Barbara; Gałan, Wojciech; Chruścicka, Barbara; Kaminska, Marta; Sochaj-Gregorczyk, Alicja; Magiera-Mularz, Katarzyna; Wang, Jun; Winiarski, Marek; Benedyk-Machaczka, Małgorzata; Kozieł, Joanna; Dubin, Grzegorz; Mydel, Piotr Mateusz (Journal article; Peer reviewed, 2024)
      Programmed death receptor 1, PD1, modulates the function of immune cells by providing inhibitory signals and constitutes the marker of immune exhaustion. Monitoring the level of PD1 promises a useful diagnostic approach ...
    • Identification and characterization of aptameric inhibitors of human neutrophil elastase 

      Malicki, Stanisław; Książek, Mirosław; Sochaj Gregorczyk, Alicja; Kaminska, Marta; Golda, Anna; Chruścicka, Barbara; Mizgalska, Danuta; Potempa, Jan; Marti, Hans Peter; Kozieł, Joanna; Wieczorek, Maciej; Pieczykolan, Jerzy; Mydel, Piotr Mateusz; Dubin, Grzegorz (Journal article; Peer reviewed, 2023)
      Human neutrophil elastase (HNE) plays a pivotal role in innate immunity, inflammation, and tissue remodeling. Aberrant proteolytic activity of HNE contributes to organ destruction in various chronic inflammatory diseases ...
    • Imaging of Clear Cell Renal Carcinoma with Immune Checkpoint Targeting Aptamer-Based Probe 

      Malicki, Stanisław; Pucelik, Barbara; Żyła, Edyta; Benedyk-Machaczka, Małgorzata; Gałan, Wojciech; Golda, Anna; Sochaj-Gregorczyk, Alicja; Kaminska, Marta; Encarnação, João Crispim; Chruścicka, Barbara; Marti, Hans Peter; Chen, Tony Jialiang; Magiera-Mularz, Katarzyna; Zięba, Bartosz; Holak, Tad A.; Dabrowski, Janusz M.; Czarna, Anna; Kozieł, Joanna; Mydel, Piotr Mateusz; Dubin, Grzegorz (Journal article; Peer reviewed, 2022-06-01)
      Immune checkpoint targeting immunotherapy has revolutionized the treatment of certain cancers in the recent years. Determination of the status of immune checkpoint expression in particular cancers may assist decision making. ...