Browsing Bergen Open Research Archive by Author "Kristensen, Gunnar S Balle"

Now showing items 1-4 of 4

    • Association Between Proportion of Nuclei With High Chromatin Entropy and Prognosis in Gynecological Cancers 

      Nielsen, Birgitte; Kleppe, Andreas; Hveem, Tarjei Sveinsgjerd; Pradhan, Manohar; Syvertsen, Rolf Anders; Nesheim, John Arne; Kristensen, Gunnar S Balle; Trovik, Jone; Kerr, David J.; Albregtsen, Fritz; Danielsen, Håvard Emil (Peer reviewed; Journal article, 2018-04-18)
      Background: Nuclear texture analysis measuring differences in chromatin structure has provided prognostic biomarkers in several cancers. There is a need for improved cell-by-cell chromatin analysis to detect nuclei with ...

    • Chromatin organisation and cancer prognosis: a pan-cancer study 

      Kleppe, Andreas; Albregtsen, Fritz; Vlatkovic, Ljiljana; Pradhan, Manohar; Nielsen, Birgitte; Hveem, Tarjei Sveinsgjerd; Askautrud, Hanne Arenberg; Kristensen, Gunnar S Balle; Nesbakken, Arild; Trovik, Jone; Wæhre, Haakon; Tomlinson, Ian; Shepherd, Neil A.; Novelli, Marco; Kerr, David J.; Danielsen, Håvard Emil (Peer reviewed; Journal article, 2018-03)
      Background: Chromatin organisation affects gene expression and regional mutation frequencies and contributes to carcinogenesis. Aberrant organisation of DNA has been correlated with cancer prognosis in analyses of the ...

    • Prognostic value of the diversity of nuclear chromatin compartments in gynaecological carcinomas 

      Kleppe, Andreas; Albregtsen, Fritz; Trovik, Jone; Kristensen, Gunnar S Balle; Danielsen, Håvard Emil (Journal article; Peer reviewed, 2020)
      Statistical texture analysis of cancer cell nuclei stained for DNA has recently been used to develop a pan-cancer prognostic marker of chromatin heterogeneity. In this study, we instead analysed chromatin organisation by ...

    • Salvage Radiation for Pelvic Relapse after Surgically Treated Endometrial Cancer 

      Lindemann, Kristina Yvonne Kathe; Smogeli, Aud Elisabeth Farstad; Småstuen, Milada Cvancarova; Bruheim, Kjersti; Trovik, Jone; Nordberg, Terje; Kristensen, Gunnar S Balle; Werner, Henrica Maria Johanna; Nakken, Ester (Journal article; Peer reviewed, 2021)
      (1) Background: This study evaluated the clinical outcome after salvage radiotherapy for first pelvic relapse after endometrial cancer (EC). (2) Methods: This multicenter retrospective study included EC patients with first ...