Blar i Bergen Open Research Archive på forfatter "Kristoffersen, Einar Klæboe"
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Cold-stored whole blood in a Norwegian emergency helicopter service: an observational study on storage conditions and product quality
Bjerkvig, Christopher Kalhagen; Sivertsen, Joar; Bråthen, Hanne Kristin; Lunde, Turid Helen Felli; Strandenes, Geir; Assmus, Jörg; Hervig, Tor; Cap, Andrew P.; Kristoffersen, Einar Klæboe; Fosse, Theodor; Apelseth, Torunn Oveland (Journal article; Peer reviewed, 2020)BACKGROUND Increasing numbers of emergency medical service agencies and hospitals are developing the capability to administer blood products to patients with hemorrhagic shock. Cold‐stored whole blood (WB) is the only ... -
Environmental pollutants in blood donors: The multicentre Norwegian donor study
Averina, Maria; Hervig, Tor; Huber, Sandra; Kjær, Mette; Kristoffersen, Einar Klæboe; Bolann, Bjørn Johan (Journal article; Peer reviewed, 2020)Objectives The aim of this study was to measure blood concentrations of environmental pollutants in Norwegian donors and evaluate the risk of pollutant exposure through blood transfusions. Background Transfused blood ... -
The immunology of the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome; what can the tonsils reveal. A literature review.
Førsvoll, Jostein Andersen; Kristoffersen, Einar Klæboe; Øymar, Knut (Peer reviewed; Journal article, 2020)Objectives: Tonsillectomy (TE) or adenotonsillectomy (ATE) may have a beneficial effect on the clinical course in children with the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome. ... -
Immunomodulation induced by stem cell mobilization and harvesting in healthy donors: Increased systemic osteopontin levels after treatment with granulocyte colony-stimulating factor
Melve, Guro Kristin; Ersvær, Elisabeth; Akkøk, Cigdem Ahaein; Ahmed, Aymen B; Kristoffersen, Einar Klæboe; Hervig, Tor; Bruserud, Øystein (Peer reviewed; Journal article, 2016-07-19)Peripheral blood stem cells from healthy donors mobilized by granulocyte colony-stimulating factor (G-CSF) and harvested by leukapheresis are commonly used for allogeneic stem cell transplantation. The frequency of severe ... -
Increased infiltration and tolerised antigen-specific CD8+ TEM cells in tumor but not peripheral blood have no impact on survival of HCMV+ glioblastoma patients
Bahador, Marzieh; Gras Navarro, Andrea; Rahman, Mohummad Aminur; Dominguez Valentin, Mev; Sarowar, Shahin; Ulvestad, Elling; Njølstad, Gro; Lie, Stein Atle; Kristoffersen, Einar Klæboe; Bratland, Eirik; Enger, Martha Chekenya (Peer reviewed; Journal article, 2017)Human cytomegalovirus (HCMV) antigens in glioblastoma (GBM) present opportunities for personalised immunotherapy. However, their presence in GBM tissue is still under debate, and evidence of their impact on functional ... -
Novel Nanoparticulate and Ionic Titanium Antigens for Hypersensitivity Testing
Høl, Paul Johan; Kristoffersen, Einar Klæboe; Gjerdet, Nils Roar; Pellowe, Amanda (Peer reviewed; Journal article, 2018-04-06)Titanium is used in a wide variety of materials ranging from medical devices to materials used in everyday life. Adverse biological reactions that could occur in patients, consumers, and workers should be monitored and ... -
Peripheral blood stem cell mobilization in healthy Donors by granulocyte colony-stimulating factor causes preferential mobilization of lymphocyte subsets
Melve, Guro Kristin; Ersvær, Elisabeth; Eide, Geir Egil; Kristoffersen, Einar Klæboe; Bruserud, Øystein (Peer reviewed; Journal article, 2018-05-02)Background: Allogeneic hematopoietic stem cell transplantation is associated with a high risk of immune-mediated post-transplant complications. Graft depletion of immunocompetent cell subsets is regarded as a possible ... -
Platelet functionality in cold-stored whole blood
Kristoffersen, Einar Klæboe; Apelseth, Torunn Oveland (Peer reviewed; Journal article, 2019)Whole blood is currently being reintroduced as a blood product to be used in massive bleeding situations because it affords plasma, red cells and platelets in a balanced ratio and in a logistical advantageous way. Questions ... -
Pretreatment of glioblastoma with bortezomib potentiates natural killer cell cytotoxicity through TRAIL/DR5 mediated apoptosis and prolongs animal survival
Gras Navarro, Andrea; Espedal, Heidi; Vareecal Joseph, Justin; Moncho, Laura Trachsel; Bahador, Marzieh; Gjertsen, Bjørn Tore; Kristoffersen, Einar Klæboe; Simonsen, Anne; Miletic, Hrvoje; Enger, Per Øyvind; Rahman, Mohummad Aminur; Enger, Martha Chekenya (Peer reviewed; Journal article, 2019-07-17)Background: Natural killer (NK) cells are potential effectors in anti-cancer immunotherapy; however only a subset potently kills cancer cells. Here, we examined whether pretreatment of glioblastoma (GBM) with the proteasome ... -
Thrombocytopaenia in the critically ill
Bruserud, Øyvind; Mosevoll, Knut Anders; Kristoffersen, Einar Klæboe; Kvåle, Reidar; Reikvam, Håkon (Journal article; Peer reviewed, 2021) -
A whole blood based resuscitation strategy in civilian medical services: Experience from a Norwegian hospital in the period 2017–2020
Hagen, Kristin Gjerde; Strandenes, Geir; Kristoffersen, Einar Klæboe; Braathen, Hanne; Sivertsen, Joar; Bjerkvig, Christopher Kalhagen; Sommerfelt-Pettersen, Nina Grindheim; Aasheim, Irmelin Beathe; Lunde, Turid Helen Felli; Hervig, Tor; Apelseth, Torunn Oveland (Journal article; Peer reviewed, 2021)Background: Civilian and military guidelines recommend early balanced transfusion to patients with life-threatening bleeding. Low titer group O whole blood was introduced as the primary blood product for resuscitation of ...