Browsing Bergen Open Research Archive by Author "Kusche-Gullberg, Marion"

Now showing items 1-3 of 3

    • The extostosin family: Proteins with many functions 

      Busse-Wicher, Marta; Wicher, Krzysztof B.; Kusche-Gullberg, Marion (Peer reviewed; Journal article, 2014-04)
      Heparan sulfates are complex sulfated molecules found in abundance at cell surfaces and in the extracellular matrix. They bind to and influence the activity of a variety of molecules like growth factors, proteases and ...

    • Fibroblast EXT1-Levels Influence Tumor Cell Proliferation and Migration in Composite Spheroids 

      Österholm, Cecilia; Lu, Ning; Lidén, Åsa; Karlsen, Tine V.; Gullberg, Donald; Reed, Rolf K.; Kusche-Gullberg, Marion (Peer reviewed; Journal article, 2012-07-25)
      Background: Stromal fibroblasts are important determinants of tumor cell behavior. They act to condition the tumor microenvironment, influence tumor growth, support tumor angiogenesis and affect tumor metastasis. Heparan ...

    • Fibroblast α11β1 Integrin Regulates Tensional Homeostasis in Fibroblast/A549 Carcinoma Heterospheroids 

      Lu, Ning; Karlsen, Tine Veronica; Reed, Rolf K.; Kusche-Gullberg, Marion; Gullberg, Donald (Peer reviewed; Journal article, 2014-07-30)
      We have previously shown that fibroblast expression of α11β1 integrin stimulates A549 carcinoma cell growth in a xenograft tumor model. To understand the molecular mechanisms whereby a collagen receptor on fibroblast can ...