Browsing Bergen Open Research Archive by Author "Kvaløy, Jan Terje"
Now showing items 1-20 of 26
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Air versus Sulfur Hexafluoride Gas Tamponade for Small and Medium-Sized Macular Holes: A Randomized Noninferiority Trial
Lindtjørn, Birger; Krohn, Jørgen Gitlesen; Haugstad, Marta; Stene-Johansen, Ingar; Austeng, Dordi; Basit, Samy; Fossen, Kristian Anker; Varhaug, Pål; Kvaløy, Jan Terje; Forsaa, Vegard Asgeir (Journal article; Peer reviewed, 2022)Purpose: To investigate whether air tamponade is noninferior to sulfur hexafluoride (SF6) gas tamponade for small (≤ 250 μm) and medium-sized (> 250 μm and ≤ 400 μm) macular holes (MHs). Design: Multicenter, randomized ... -
Anastomotic leak after surgery for colon cancer and effect on long‐term survival
Stormark, Kjartan; Krarup, Peter-Martin; Sjövall, Annika; Søreide, Kjetil; Kvaløy, Jan Terje; Nordholm-Carstensen, Andreas; Nedrebø, Bjørn Steinar Olden; Kørner, Hartwig (Journal article; Peer reviewed, 2020)Aim An anastomotic leak after surgery for colon cancer is a recognized complication but how it may adversely affect long‐term survival is less clear because data are scarce. The aim of the study was to investigate the ... -
Cytokine network in adults with falciparum malaria and HIV-1: increased IL-8 and IP-10 levels are associated with disease severity
Berg, Åse; Patel, Sam; Gonca, Miguel; Catarina, David; Otterdal, Kari; Ueland, Thor; Dalen, Ingvild; Kvaløy, Jan Terje; Mollnes, Tom Eirik; Aukrust, Pål; Langeland, Nina (Peer reviewed; Journal article, 2014-12-11)Background Co-infection with malaria and HIV increases the severity and mortality of both diseases, but the cytokine responses related to this co-infection are only partially characterised. The aim of this study was to ... -
Determination of lower cut-off levels of adalimumab associated with biochemical remission in Crohn's disease
Carlsen, Arne; Omdal, Roald; Karlsen, Lars Normann; Kvaløy, Jan Terje; Aabakken, Lars; Steinsbø, Øyvind; Bolstad, Nils; Warren, David; Lundin, Knut Erik Aslaksen; Grimstad, Tore (Peer reviewed; Journal article, 2020)Background and Aim: Adalimumab is administered and dosed using a standardized treatment regimen. Although therapeutic drug monitoring (TDM) may help optimize treatment efficacy, the lower cut‐off concentration of adalimumab ... -
Epidemiology and classification of gastroenteropancreatic neuroendocrine neoplasms using current coding criteria
Sandvik, Oddvar Mathias; Søreide, Kjetil; Gudlaugsson, Einar; Kvaløy, Jan Terje; Søreide, Jon Arne (Peer reviewed; Journal article, 2016-02)Background: The lack of uniform criteria for coding of gastroenteropancreatic neuroendocrine neoplasia (GEP-NEN) has hampered previous epidemiological studies. The epidemiology of GEP-NEN was investigated in this study ... -
Epidemiology of abdominal trauma: An age- and sex-adjusted incidence analysis with mortality patterns
Larsen, Johannes Wiik; Søreide, Kjetil; Søreide, Jon Arne; Tjosevik, Kjell E; Kvaløy, Jan Terje; Thorsen, Kenneth (Journal article; Peer reviewed, 2022)Purpose Abdominal injuries may occur in up to one-third of all patients who suffer severe trauma, but little is known about epidemiological trends and characteristics in a Northern European setting. This study investigated ... -
The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside
Grøsvik, Kristin; Tesfahun, Almaz Nigatu; Muruzábal-Lecumberri, Izaskun; Haugland, Gyri Teien; Leiros, Ingar; Ruoff, Peter; Kvaløy, Jan Terje; Knævelsrud, Ingeborg; Ånensen, Hilde; Alexeeva, Marina; Sato, Kousuke; Matsuda, Akira; Alseth, Ingrun; Klungland, Arne; Bjelland, Svein (Journal article; Peer reviewed, 2020)The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine ... -
Factors predicting the use of therapeutic hypothermia and survival in unconscious out-of-hospital cardiac arrest patients admitted to the ICU
Lindner, Thomas Werner; Langørgen, Jørund; Sunde, Kjetil; Larsen, Alf Inge; Kvaløy, Jan Terje; Heltne, Jon-Kenneth; Drægni, Tomas; Søreide, Eldar (Peer reviewed; Journal article, 2013-07-23)Introduction: Therapeutic hypothermia (TH) after out-of-hospital cardiac arrest (OHCA) was adopted early in Norway. Since 2004 the general recommendation has been to cool all unconscious OHCA patients treated in the intensive ... -
Fatigue: a frequent and biologically based phenomenon in newly diagnosed celiac disease
Skjellerudsveen, Berit Mære; Omdal, Roald; Hetta, Anne Kristine; Kvaløy, Jan Terje; Aabakken, Lars; Skoie, Inger Marie; Grimstad, Tore Bjørn (Journal article; Peer reviewed, 2022)Fatigue is increasingly recognized as a major complaint in patients with chronic inflammatory and autoimmune diseases. Although fatigue is assumed to represent a significant problem in celiac disease, existing knowledge ... -
Frequent refresher training on newborn resuscitation and potential impact on perinatal outcome over time in a rural Tanzanian hospital: An observational study
Mduma, Estomih; Kvaløy, Jan Terje; Søreide, Eldar; Svensen, Erling; Mdoe, Paschal Francis; Perlman, Jeffrey; Johnson, Caroline Amy; Hussein, Kidanto; Ersdal, Hege Langli (Peer reviewed; Journal article, 2019)Objectives: Globally, perinatal mortality remains high, especially in sub-Saharan countries, mainly because of inadequate obstetric and newborn care. Helping Babies Breathe (HBB) resuscitation training as part of a continuous ... -
Heat shock proteins and chronic fatigue in primary Sjögren's syndrome
Bårdsen, Kjetil; Mæland, Mari; Kvaløy, Jan Terje; Norheim, Katrine Brække; Jonsson, Grete; Omdal, Roald (Peer reviewed; Journal article, 2016)Fatigue occurs frequently in patients with cancer, neurological diseases and chronic inflammatory diseases, but the biological mechanisms that lead to and regulate fatigue are largely unknown. When the innate immune system ... -
Heat-shock protein 90α in plasma reflects severity of fatigue in patients with Crohn’s disease
Grimstad, Tore; Kvivik, Ingeborg; Kvaløy, Jan Terje; Aabakken, Lars; Omdal, Roald (Peer reviewed; Journal article, 2020)Heat-shock proteins (HSPs) are evolutionarily conserved proteins with important cellular homeostasis functions during harmful conditions, including inflammation. Some HSPs are secreted extracellularly and act on distant ... -
High mobility group box 1 and a network of other biomolecules influence fatigue in patients with Crohn’s disease
Kvivik, Ingeborg; Grimstad, Tore Bjørn; Bårdsen, Kjetil; Jonsson, Grete; Kvaløy, Jan Terje; Omdal, Roald (Journal article; Peer reviewed, 2023)Background Fatigue is common in patients with chronic inflammatory and autoimmune diseases, often with a severe impact on the patient’s daily life. From a biological point of view, fatigue can be regarded as an element ... -
Importance of endocrine treatment adherence and persistence in breast cancer survivorship: a systematic review
Eliassen, Finn; Blåfjelldal, Vibeke; Helland, Thomas; Hjorth, Cathrine Fonnesbech; Hølland, Kari; Lode, Lise; Bertelsen, Bjørn-Erik; Janssen, Emiel; Mellgren, Gunnar; Kvaløy, Jan Terje; Søiland, Håvard; Lende, Tone Hoel (Journal article; Peer reviewed, 2023)Purpose Adjuvant endocrine treatment is essential for treating luminal subtypes of breast cancer, which constitute 75% of all breast malignancies. However, the detrimental side effects of treatment make it difficult for ... -
Influence of pre-operative oral carbohydrate loading vs. standard fasting on tumor proliferation and clinical outcome in breast cancer patients - a randomized trial
Lende, Tone Hoel; Austdal, Marie; Varhaugvik, Anne Elin; Skaland, Ivar; Gudlaugsson, Einar; Kvaløy, Jan Terje; Akslen, Lars A.; Søiland, Håvard; Janssen, Emiel; Baak, Jan P.A. (Peer reviewed; Journal article, 2019-11-08)Background: Conflicting results have been reported on the influence of carbohydrates in breast cancer. Objective: To determine the influence of pre-operative per-oral carbohydrate load on proliferation in breast tumors. ... -
Interleukin-1-related activity and hypocretin-1 in cerebrospinal fluid contribute to fatigue in primary Sjögren’s syndrome
Bårdsen, Kjetil; Brede, Cato; Kvivik, Ingeborg; Kvaløy, Jan Terje; Jonsdottir, Kristin; Tjensvoll, Anne Bolette; Ruoff, Peter; Omdal, Roald (Journal article; Peer reviewed, 2019)Background Fatigue is a common and sometimes debilitating phenomenon in primary Sjögren’s syndrome (pSS) and other chronic inflammatory diseases. We aimed to investigate how IL-1 β-related molecules and the neuropeptide ... -
Laparoscopic rectal cancer resection yields comparable clinical and oncological results with shorter hospital stay compared to open access: a 5-year national cohort
Myrseth, Elisabeth; Gjessing, Petter Fosse; Nymo, Linn Såve; Kørner, Hartwig; Kvaløy, Jan Terje; Norderval, Stig (Journal article; Peer reviewed, 2023)Purpose Although widely applied, the results following laparoscopic rectal resection (LRR) compared to open rectal resection (ORR) are still debated. The aim of this study was to assess clinical short- and long-term ... -
Less, but not gone—gluten-free diet effects on fatigue in celiac disease: a prospective controlled study
Skjellerudsveen, Berit Mære; Omdal, Roald; Hetta, Anne Kristine; Kvaløy, Jan Terje; Aabakken, Lars; Skoie, Inger Marie; Grimstad, Tore Bjørn (Journal article; Peer reviewed, 2023)Introduction: Fatigue is a frequent complaint in patients with celiac disease. A gluten-free diet is the only established treatment for celiac disease, but how this diet influences fatigue is uncertain. We aimed to investigate ... -
Long-Term Outcomes After Open Repair for Ruptured Abdominal Aortic Aneurysm
Reite, Andreas; Søreide, Kjetil; Kvaløy, Jan Terje; Vetrhus, Morten (Journal article; Peer reviewed, 2020-03-09)Background Early mortality in ruptured abdominal aneurysm (rAAA) is high, but data on long-term outcome are scarce. The aim of this study was to investigate the long-term outcome in survivors after open surgery for rAAA ... -
Low Z-4OHtam concentrations are associated with adverse clinical outcome among early stage premenopausal breast cancer patients treated with adjuvant tamoxifen
Helland, Thomas; Naume, Bjørn; Hustad, Steinar; Bifulco, Ersilia; Kvaløy, Jan Terje; Sætersdal, Anna Barbro; Synnestvedt, Marit; Lende, Tone Hoel; Gilje, Bjørnar; Mjaaland, Ingvil; Weyde, Kjetil; Blix, Egil Støre; Wiedswang, Gro; Borgen, Elin; Hertz, Daniel Louis; Janssen, Emiel; Mellgren, Gunnar; Søiland, Håvard (Journal article; Peer reviewed, 2021)Low steady‐state levels of active tamoxifen metabolites have been associated with inferior treatment outcomes. In this retrospective analysis of 406 estrogen receptor‐positive breast cancer (BC) patients receiving adjuvant ...