Blar i Bergen Open Research Archive på forfatter "Kvistad, Christopher Elnan"
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Autologous hematopoietic stem cell transplantation for multiple sclerosis: Long-term follow-up data from Norway
Kvistad, Christopher Elnan; Lehmann, Anne Kristine; Stokke, Silje Agnethe; Holmøy, Trygve; Lorentzen, Åslaug Rudjord; Trovik, Linn; Kristoffersen, Einar Klæboe; Bø, Lars; Torkildsen, Øivind (Journal article; Peer reviewed, 2024)Background: Autologous hematopoietic stem cell transplantation (HSCT) is a potent treatment option for patients with aggressive relapsing-remitting multiple sclerosis (RRMS). Objective: To evaluate long-term outcomes ... -
Clinical manifestation of acute cerebral infarcts in multiple arterial territories
Novotny, Vojtech; Aarli, Sander Johan; Netland Khanevski, Andrej; Bjerkreim, Anna Therese; Kvistad, Christopher Elnan; Fromm, Annette; Waje-Andreassen, Ulrike; Naess, Halvor; Thomassen, Lars; Logallo, Nicola (Journal article; Peer reviewed, 2021)Objectives: We aimed to assess frequencies and radiological aspects of single- and multiterritory clinical manifestation among patients with acute cerebral infarcts in multiple arterial territories (MACI). Materials & ... -
The Course of Carotid Plaque Vulnerability Assessed by Advanced Neurosonology
Aarli, Sander Johan; Thomassen, Lars; Waje-Andreassen, Ulrike; Logallo, Nicola; Kvistad, Christopher Elnan; Næss, Halvor; Fromm, Annette (Journal article; Peer reviewed, 2021-08-20)Background: Carotid artery atherosclerosis is a major risk factor for ischemic stroke. This risk is related to plaque vulnerability and is characterized by plaque morphology, intraplaque neovascularization, and cerebral ... -
Does a history of migraine affect the rate of thrombolysis in young stroke patients?
Øygarden, Halvor; Kvistad, Christopher Elnan; Thomassen, Lars; Waje-Andreassen, Ulrike; Næss, Halvor (Peer reviewed; Journal article, 2013)Background. Migraine is prevalent in young patients and a frequent stroke mimic. To distinguish stroke mimics from true stroke can be difficult, and there is a possibility of misdiagnosing a stroke as a migrainous attack ... -
A family history of stroke is associated with increased intima-media thickness in young ischemic Stroke - The norwegian stroke in the young study (NOR-SYS)
Øygarden, Halvor; Fromm, Annette; Sand, Kristin Modalsli; Kvistad, Christopher Elnan; Eide, Geir Egil; Thomassen, Lars; Næss, Halvor; Waje-Andreassen, Ulrike (Peer reviewed; Journal article, 2016-08-09)Background and Purpose: Positive family history (FH+) of cardiovascular disease (CVD) is a risk factor for own CVD. We aimed to analyze the effect of different types of FH (stroke, coronary heart disease (CHD), peripheral ... -
The neuroprotective potential of mesenchymal stem cells from bone marrow and human exfoliated deciduous teeth in a murine model of demyelination
Kråkenes, Torbjørn; Wergeland, Stig; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Fromreide, Siren; Costea, Daniela Elena; Mustafa, Kamal Babikeir Elnour; Bø, Lars; Kvistad, Christopher Elnan (Journal article; Peer reviewed, 2023)Introduction Multiple sclerosis (MS) is characterized by chronic inflammation, demyelination, and axonal degeneration within the central nervous system (CNS), for which there is no current treatment available with the ... -
NOR-SASS (Norwegian Sonothrombolysis in Acute Stroke Study): Randomized controlled contrast-enhanced sonothrombolysis in an unselected acute ischemic stroke population
Nacu, Aliona; Kvistad, Christopher Elnan; Næss, Halvor; Øygarden, Halvor; Logallo, Nicola; Assmus, Jörg; Waje-Andreassen, Ulrike; Kurz, Kathinka Dæhli; Neckelmann, Gesche F; Thomassen, Lars (Peer reviewed; Journal article, 2016-02)Background and Purpose—The NOR-SASS (Norwegian Sonothrombolysis in Acute Stroke Study) aimed to assess effect and safety of contrast-enhanced ultrasound treatment in an unselected acute ischemic stroke population. ... -
The Norwegian tenecteplase stroke trial (NOR-TEST): randomised controlled trial of tenecteplase vs. alteplase in acute ischaemic stroke
Logallo, Nicola; Kvistad, Christopher Elnan; Nacu, Aliona; Næss, Halvor; Waje-Andreassen, Ulrike; Asmuss, Jörg; Aamodt, Anne Hege; Lund, Christian; Kurz, Martin; Rønning, Ole Morten; Salvesen, Rolf; Idicula, Titto T.; Thomassen, Lars (Peer reviewed; Journal article, 2014-05-15)Background: Alteplase is the only approved thrombolytic agent for acute ischaemic stroke. The overall benefit from alteplase is substantial, but some evidence indicates that alteplase also has negative effects on the ... -
Persistent microembolic signals in the cerebral circulation on transcranial Doppler after intravenous sulfur hexafluoride microbubble infusion
Aarli, Sander Johan; Novotny, Vojtech; Thomassen, Lars; Kvistad, Christopher Elnan; Logallo, Nicola; Fromm, Annette (Peer reviewed; Journal article, 2020)Background and purpose: Microembolic signals (MES) are detectable by transcranial Doppler monitoring and associated with increased risk of first or recurrent ischemic stroke. MES detection can also illuminate stroke etiology ... -
A pragmatic approach to sonothrombolysis in acute ischaemic stroke: The Norwegian randomised controlled sonothrombolysis in acute stroke study (NOR-SASS)
Nacu, Aliona; Kvistad, Christopher Elnan; Logallo, Nicola; Næss, Halvor; Waje-Andreassen, Ulrike; Aamodt, Anne Hege; Solhoff, Ragnar; Lund, Christian; Tobro, Håkon; Rønning, Ole Morten; Salvesen, Rolf; Idicula, Titto; Thomassen, Lars (Peer reviewed; Journal article, 2015-07-11)Background: Ultrasound accelerates thrombolysis with tPA (sonothrombolysis). Ultrasound in the absence of tPA also accelerates clot break-up (sonolysis). Adding intravenous gaseous microbubbles may potentiate the effect ... -
Recanalization in cerebral ischemia. A register-based study
Kvistad, Christopher Elnan (Doctoral thesis, 2015-02-20) -
Recurrent ischemic stroke: Incidence, predictors, and impact on mortality
Khanevski, Andrej; Bjerkreim, Anna Therese; Novotny, Vojtech; Næss, Halvor; Thomassen, Lars; Logallo, Nicola; Kvistad, Christopher Elnan (Peer reviewed; Journal article, 2019)Background and purpose: Recurrent ischemic stroke (IS) or TIA is frequent with a considerable variation in incidence and mortality across populations. Current data on stroke recurrence and mortality are useful to examine ... -
Safety and Clinical Efficacy of Mesenchymal Stem Cell Treatment in Traumatic Spinal Cord Injury, Multiple Sclerosis and Ischemic Stroke – A Systematic Review and Meta-Analysis
Kvistad, Christopher Elnan; Kråkenes, Torbjørn; Gjengedal, Gudveig Cecilie Gjerde; Mustafa, Kamal Babikeir Elnour; Rekand, Tiina; Bø, Lars (Journal article; Peer reviewed, 2022-05-30)Background: Mesenchymal stem cells (MSCs) is an attractive candidate in regenerative research and clinical trials have assessed their therapeutic potential in different neurological conditions with disparate etiologies. ... -
Tenecteplase, 0.4 mg/kg, in Moderate and Severe Acute Ischemic Stroke: A Pooled Analysis of NOR-TEST and NOR-TEST 2A
Novotny, Vojtech; Kvistad, Christopher Elnan; Næss, Halvor; Logallo, Nicola; Fromm, Annette; Khanevski, Andrej; Thomassen, Lars (Journal article; Peer reviewed, 2023)Background: The optimal dose of tenecteplase in acute ischemic stroke remains to be defined. We present a pooled analysis of the 2 NOR‐TESTs (Norwegian Tenecteplase Stroke Trials) exploring the efficacy and safety of ... -
The Therapeutic Mechanisms of Mesenchymal Stem Cells in MS—A Review Focusing on Neuroprotective Properties
Gavasso, Sonia; Kråkenes, Torbjørn; Olsen, Håkon; Evjenth, Elisabeth Claire; Ytterdal, Marie; Haugsøen, Jonas Bull; Kvistad, Christopher Elnan (Journal article; Peer reviewed, 2024-01-23)In multiple sclerosis (MS), there is a great need for treatment with the ability to suppress compartmentalized inflammation within the central nervous system (CNS) and to promote remyelination and regeneration. Mesenchymal ...