Browsing Bergen Open Research Archive by Author "Löhr, Iren Høyland"
Now showing items 1-10 of 10
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Convergence of virulence and MDR in a single plasmid vector in MDR Klebsiella pneumoniae ST15
Lam, Margaret M.C.; Wyres, Kelly L.; Wick, Ryan R.; Judd, Louise M.; Fostervold, Aasmund; Holt, Kathryn E.; Löhr, Iren Høyland (Peer reviewed; Journal article, 2019)Background: MDR and hypervirulence (hv) are typically observed in separate Klebsiella pneumoniae populations. However, convergent strains with both properties have been documented and potentially pose a high risk to public ... -
Emergence and rapid global dissemination of CTX-M-15-associated Klebsiella pneumoniae strain ST307
Wyres, Kelly L.; Hawkey, Jane; Hetland, Marit; Fostervold, Aasmund; Wick, Ryan R.; Judd, Louise M.; Hamidian, Mohammad; Howden, Benjamin P.; Löhr, Iren Høyland; Holt, Kathryn E. (Peer reviewed; Journal article, 2019)Objectives: Recent reports indicate the emergence of a new carbapenemase-producing Klebsiella pneumoniae clone, ST307. We sought to better understand the global epidemiology and evolution of this clone and evaluate its ... -
Extended-spectrum β-lactamase producing Klebsiella pneumoniae. A neonatal intensive care unit outbreak, long-term colonization in children and plasmid characteristics
Löhr, Iren Høyland (Doctoral thesis, 2014-12-19)Background: The increasing level of antimicrobial resistance among clinical relevant bacteria, especially the increasing prevalence of extended-spectrum β-lactamase (ESBL) producing Enterobacteriaceae, is of great concern ... -
Gastrointestinal carriage of Klebsiella pneumoniae in a general adult population: a cross-sectional study of risk factors and bacterial genomic diversity
Raffelsberger, Niclas Peter; Hetland, Marit Andrea Klokkhammer; Svendsen, Kristian; Småbrekke, Lars; Löhr, Iren Høyland; Andreassen, Lotte; Brisse, Sylvain; Holt, Kathryn E.; Sundsfjord, Arnfinn; Samuelsen, Ørjan; Gravningen, Kirsten Midttun (Journal article; Peer reviewed, 2021)Antibiotic resistant Klebsiella pneumoniae is a leading public health threat and gastrointestinal carriage is an established risk factor for subsequent infections during hospitalization. Our study contributes new knowledge ... -
Insights into the genetic diversity, antibiotic resistance and pathogenic potential of Klebsiella pneumoniae from the Norwegian marine environment using whole-genome analysis
Håkonsholm, Fredrik; Hetland, Marit Andrea Klokkhammer; Svanevik, Cecilie Smith; Lunestad, Bjørn Tore; Löhr, Iren Høyland; Marathe, Nachiket Prakash (Journal article; Peer reviewed, 2022)Klebsiella pneumoniae (Kp) can cause hospital- and community acquired infections. Although, Kp is widespread in the environment, very little is known about the genetic diversity and pathogenicity of Kp from the marine ... -
A nationwide genomic study of clinical Klebsiella pneumoniae in Norway 2001–15: introduction and spread of ESBLs facilitated by clonal groups CG15 and CG307
Fostervold, Aasmund; Hetland, Marit Andrea Klokkhammer; Bakksjø, Ragna-Johanne; Bernhoff, Eva; Holt, Kathryn E.; Samuelsen, Ørjan; Simonsen, Gunnar Skov; Sundsfjord, Arnfinn; Wyres, Kelly L.; Löhr, Iren Høyland (Journal article; Peer reviewed, 2022)Objectives To use the nationwide Norwegian surveillance programme on resistant microbes in humans (NORM) to address longitudinal changes in the population structure of Klebsiella pneumoniae isolates from 2001–15, focusing ... -
The Performances of Three Commercially Available Assays for the Detection of SARS‐CoV‐2 Antibodies at Different Time Points Following SARS‐CoV‐2 Infection
Syre, Heidi; Obreque, Marius Eduardo Brå; Dalen, Ingvild; Riis, Åse Garløv; Berg, Åse; Löhr, Iren Høyland; Sundal, Jon; Kleppe, Lars Kåre Selland; Vadla, May Sissel; Lenning, Ole Bernt; Olofsson, Jan Stefan; Mohn, Kristin Greve-Isdahl; Tøndel, Camilla; Blomberg, Bjørn; Trieu, Mai Chi; Langeland, Nina; Cox, Rebecca Jane (Journal article; Peer reviewed, 2022)The aim of this study was to evaluate the performances of three commercially available antibody assays for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies at different time points ... -
Persistence of a pKPN3-like CTX-M-15-encoding IncFIIK plasmid in a Klebsiella pneumonia ST17 host during two years of intestinal colonization
Löhr, Iren Høyland; Hülter, Nils Fredrik; Bernhoff, Eva; Johnsen, Pål Jarle; Sundsfjord, Arnfinn; Naseer, Mohammed Umaer (Peer reviewed; Journal article, 2015-03-04)Objectives. To characterize the CTX-M-15-encoding plasmid in a Klebsiella pneumoniae ST17 strain, responsible for an outbreak at a Norwegian neonatal intensive care unit and subsequent colonization of affected children for ... -
Rapid high-resolution detection of colistin resistance in Gram-negative bacteria using flow cytometry: a comparison with broth microdilution, a commercial screening test and WGS
Ekelund, Oskar; Hetland, Marit Andrea Klokkhammer; Löhr, Iren Høyland; Schön, Thomas; Somajo, Sofia (Journal article; Peer reviewed, 2021)Background Even though both EUCAST and CLSI consider broth microdilution (BMD) as the reference method for antimicrobial susceptibility testing (AST) of colistin, the method exhibits potential flaws related to properties ... -
Use of probiotics to reduce infections and death and prevent colonization with extended-spectrum beta-lactamase (ESBL)- producing bacteria among newborn infants in Tanzania (ProRIDE Trial): study protocol for a randomized controlled clinical trial
Kuwelker, Kanika; Langeland, Nina; Löhr, Iren Høyland; Gidion, Joshua; Manyahi, Joel; Moyo, Sabrina John; Blomberg, Bjørn; Klingenberg, Claus (Journal article; Peer reviewed, 2021)Background Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) has emerged as an urgent global health threat and is by the World Health Organization ranked as priority 1 among pathogens in need of new ...