Browsing Bergen Open Research Archive by Author "Løland, Kjetil Halvorsen"
Now showing items 1-6 of 6
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The Association between Progression of Atherosclerosis and the Methylated Amino Acids Asymmetric Dimethylarginine and Trimethyllysine
Løland, Kjetil Halvorsen; Bleie, Øyvind; Borgeraas, Heidi; Strand, Elin; Ueland, Per Magne; Svardal, Asbjørn; Nordrehaug, Jan Erik; Nygård, Ottar (Peer reviewed; Journal article, 2013-05-29)Objective: We previously showed that treatment with folic acid (FA)/B12 was associated with more rapid progression of coronary artery disease (CAD). High doses of FA may induce methylation by increasing the availability ... -
Circulating trimethyllysine and risk of acute myocardial infarction in patients with suspected stable coronary heart disease
Bjørnestad, Espen Ø.; Olset, Hilde; Dhar, Indu; Løland, Kjetil Halvorsen; Pedersen, Eva Ringdal; Svingen, Gard Frodahl Tveitevåg; Svardal, Asbjørn M.; Berge, Rolf K; Ueland, Per Magne; Tell, Grethe S.; Nilsen, Dennis W.T.; Jan E., Nordrehaug; Nygaard, Ellisif; Nygård, Ottar (Journal article; Peer reviewed, 2020)Background The carnitine precursor trimethyllysine (TML) is associated with progression of atherosclerosis, possibly through a relationship with trimethylamine-N-oxide (TMAO). Riboflavin is a cofactor in TMAO synthesis. ... -
Effect of Folic Acid Supplementation on Levels of Circulating Monocyte Chemoattractant Protein-1 and the Presence of Intravascular Ultrasound Derived Virtual Histology Thin-Cap Fibroatheromas in Patients with Stable Angina Pectoris
Løland, Kjetil Halvorsen; Bleie, Øyvind; Strand, Elin; Ueland, Per Magne; Nordrehaug, Jan Erik; Garcia-Garcia, Hector M.; Serruys, Patrick W.; Nygård, Ottar (Peer reviewed; Journal article, 2013-07-25)Background: Virtual Histology Intravascular Ultrasound (VH–IVUS) may be used to detect early signs of unstable coronary artery disease. Monocyte Chemoattractant Protein-1 (MCP-1) is linked with coronary atherosclerosis and ... -
Folic acid supplementation and biomarkers of progression of sub-clinical coronary atherosclerosis in patients with stable angina pectoris. A WENBIT sub-study based on coronary angiography and intravascular ultrasound
Løland, Kjetil Halvorsen (Doctoral thesis, 2014-04-09)Background: Coronary artery disease (CAD) is the leading cause of death in the world. Total plasma homocysteine (tHcy) is an independent risk factor for CAD, and while tHcy is lowered by folic acid (FA)/vitamin B12 (B12) ... -
Glycated hemoglobin and long-term prognosis in patients with suspected stable angina pectoris without diabetes mellitus: A prospective cohort study
Rebnord, Eirik Wilberg; Pedersen, Eva Kristine Ringdal; Strand, Elin; Svingen, Gard Frodahl Tveitevåg; Meyer, Klaus; Schartum-Hansen, Hall; Løland, Kjetil Halvorsen; Seifert, Reinhard; Ueland, Per Magne; Nilsen, Dennis W. T.; Nordrehaug, Jan Erik; Nygård, Ottar (Peer reviewed; Journal article, 2015-05)Objective: Associations of glycated hemoglobin A1c (HbA1c) levels to incident coronary and cardiovascular events among non-diabetic patients with coronary artery disease are unclear. We investigated relations of HbA1c to ... -
Use of loop diuretics is associated with increased mortality in patients with suspected coronary artery disease, but without systolic heart failure or renal impairment: an observational study using propensity score matching
Schartum-Hansen, Hall; Løland, Kjetil Halvorsen; Svingen, Gard Frodahl Tveitevåg; Seifert, Reinhard; Pedersen, Eva Ringdal; Nordrehaug, Jan Erik; Bleie, Øyvind; Ebbing, Marta; Berge, Christ; Nilsen, Dennis W.T.; Nygård, Ottar (Peer reviewed; Journal article, 2015-06-01)Background Loop diuretics are widely used in patients with heart and renal failure, as well as to treat hypertension and peripheral edema. However, there are no randomized, controlled trials (RCT) evaluating their long ...