Blar i Bergen Open Research Archive på forfatter "Langeland, Nina"
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Adenosine Deaminase Activity Is a Sensitive Marker for the Diagnosis of Tuberculous Pleuritis in Patients with Very Low CD4 Counts
Baba, Kamaldeen; Hoosen, Anwar A.; Langeland, Nina; Dyrhol-Riise, Anne Ma (Peer reviewed; Journal article, 2008-07-30)Background: Adenosine Deaminase Activity (ADA) is a commonly used marker for the diagnosis of tuberculous pleural effusion. There has been concern about its usefulness in immunocompromised patients, especially HIV positive ... -
Aetiology, antimicrobial therapy and outcome of patients with community acquired severe sepsis: a prospective study in a Norwegian university hospital
Nygård, Siri Tandberg; Langeland, Nina; Flaatten, Hans; Fanebust, Rune; Haugen, Oddbjørn; Skrede, Steinar (Peer reviewed; Journal article, 2014-03-04)Background: Severe sepsis is recognized as an inflammatory response causing organ dysfunction in patients with infection. Antimicrobial therapy is the mainstay of treatment. There is an ongoing demand for local surveillance ... -
Age specific aetiological agents of diarrhoea in hospitalized children aged less than five years in Dar es Salaam, Tanzania
Moyo, Sabrina John; Njølstad, Gro; Matee, Mecky I.; Kitundu, Jesse; Myrmel, Helge; Mylvaganam, Haima; Maselle, Samwel Y.; Langeland, Nina (Peer reviewed; Journal article, 2011-02-23)Background This study aimed to determine the age-specific aetiologic agents of diarrhoea in children aged less than five years. The study also assessed the efficacy of the empiric treatment of childhood diarrhoea using ... -
Antimicrobial resistance predicts death in Tanzanian children with bloodstream infections: a prospective cohort study
Blomberg, Bjørn; Manji, Karim P.; Urassa, Willy K.; Tamim, Bushir S.; Mwakagile, Davis S. M.; Jureen, Roland; Msangi, Viola; Tellevik, Marit Gjerde; Holberg-Petersen, Mona; Harthug, Stig; Maselle, Samwel Y.; Langeland, Nina (Peer reviewed; Journal article, 2007-05-22)Background: Bloodstream infection is a common cause of hospitalization, morbidity and death in children. The impact of antimicrobial resistance and HIV infection on outcome is not firmly established. Methods: We assessed ... -
Assessment of malaria real-time PCR methods and application with focus on lowlevel parasitaemia
Haanshuus, Christel Gill; Mørch, Kristine; Blomberg, Bjørn; Strøm, Gro Elizabeth Ann; Langeland, Nina; Hanevik, Kurt; Mohn, Stein Christian (Peer reviewed; Journal article, 2019-07-05)In epidemiological surveys and surveillance the application of molecular tools is essential in detecting submicroscopic malaria. A genus-specific conventional cytochrome b (cytb) PCR has shown high sensitivity in field ... -
Bacteraemia, Malaria, and Case Fatality Among Children Hospitalized With Fever in Dar es Salaam, Tanzania
Moyo, Sabrina John; Manyahi, Joel; Blomberg, Bjørn; Tellevik, Marit Gjerde; Masoud, Nahya Salim; Aboud, Said; Manji, Karim; Roberts, Adam P.; Hanevik, Kurt; Mørch, Kristine; Langeland, Nina (Journal article; Peer reviewed, 2020)Background: Febrile illness is the commonest cause of hospitalization in children <5 years in sub-Saharan Africa, and bacterial bloodstream infections and malaria are major causes of death. Methods: From March 2017 to ... -
CD64 as a potential biomarker in septic arthritis
Oppegaard, Oddvar; Skodvin, Brita; Halse, Anne-Kristine; Langeland, Nina (Peer reviewed; Journal article, 2013-06-19)Background Traditional inflammatory markers are generally unhelpful in discerning septic arthritis from inflammatory joint disease due to their lack of specificity. We wished to explore the discriminatory power of the novel ... -
Challenges in diagnosing paediatric malaria in Dar es Salaam, Tanzania
Strøm, Gro Elizabeth Ann; Haanshuus, Christel Gill; Fataki, Maulidi; Langeland, Nina; Blomberg, Bjørn (Peer reviewed; Journal article, 2013-07-03)Background: Malaria is a major cause of paediatric morbidity and mortality. As no clinical features clearly differentiate malaria from other febrile illnesses, and malaria diagnosis is challenged by often lacking laboratory ... -
Challenges in diagnosing pediatric malaria in Dar es Salaam, Tanzania
Strøm, Gro Elizabeth Ann; Haanshuus, Christel Gill; Moyo, Sabrina John; Fataki, Maulidi; Langeland, Nina; Blomberg, Bjørn (Conference object; Peer reviewed, 2012-10-15) -
Chronic fatigue syndrome 5 years after giardiasis: differential diagnoses, characteristics and natural course
Mørch, Kristine; Hanevik, Kurt; Rivenes, Ann Christin; Bødtker, Jørn; Næss, Halvor; Stubhaug, Bjarte; Wensaas, Knut-Arne; Rørtveit, Guri; Eide, Geir Egil; Hausken, Trygve; Langeland, Nina (Peer reviewed; Journal article, 2013-02-12)Background: A high prevalence of chronic fatigue has previously been reported following giardiasis after a large waterborne outbreak in Bergen, Norway in 2004. The aim of this study was to describe and evaluate differential ... -
Cytokine network in adults with falciparum malaria and HIV-1: increased IL-8 and IP-10 levels are associated with disease severity
Berg, Åse; Patel, Sam; Gonca, Miguel; Catarina, David; Otterdal, Kari; Ueland, Thor; Dalen, Ingvild; Kvaløy, Jan Terje; Mollnes, Tom Eirik; Aukrust, Pål; Langeland, Nina (Peer reviewed; Journal article, 2014-12-11)Background Co-infection with malaria and HIV increases the severity and mortality of both diseases, but the cytokine responses related to this co-infection are only partially characterised. The aim of this study was to ... -
The decline of the impetigo epidemic caused by the epidemic European fusidic acid-resistant impetigo clone: an 11.5-year population-based incidence study from a community in Western Norway
Rørtveit, Sverre; Skutlaberg, Dag Harald; Langeland, Nina; Rørtveit, Guri (Peer reviewed; Journal article, 2014-12)Background: From around the year 2000, Northern Europe experienced a rise in impetigo caused by Staphylococcus aureus resistant to fusidic acid. A single clone of S. aureus was found to be the bacterial pathogen involved ... -
Development of functional gastrointestinal disorders after Giardia lamblia infection
Hanevik, Kurt; Dizdar, Vernesa; Langeland, Nina; Hausken, Trygve (Peer reviewed; Journal article, 2009-04-21)Background: Functional gastrointestinal disorders (FGID) may occur following acute gastroenteritis. This long-term complication has previously not been described after infection with the non-invasive protozoan Giardia ... -
Early Response in Cellulitis: A Prospective Study of Dynamics and Predictors
Bruun, Trond; Oppegaard, Oddvar; Hufthammer, Karl Ove; Langeland, Nina; Skrede, Steinar (Peer reviewed; Journal article, 2016)Background: Skin and soft tissue infections are common reasons for medical care. Use of broad-spectrum therapy and costs have increased. Assessment of early treatment response has been given a central role both in clinical ... -
emm gene diversity, superantigen gene profiles and presence of SlaA among clinical isolates of group A, C and G streptococci from western Norway
Kittang, Bård Reiakvam; Skrede, Steinar; Langeland, Nina; Haanshuus, Christel Gill; Mylvaganam, Haima (Peer reviewed; Journal article, 2010-11-20)In order to investigate molecular characteristics of beta-hemolytic streptococcal isolates from western Norway, we analysed the entire emm gene sequences, obtained superantigen gene profiles and determined the prevalence ... -
Epidemiology and impact on all-cause mortality of sepsis in Norwegian hospitals: A national retrospective study
Knoop, Siri Tandberg; Skrede, Steinar; Langeland, Nina; Flaatten, Hans (Peer reviewed; Journal article, 2017-11-17)Background: Although sepsis is the leading cause of death from infection, there are few population-level epidemiological sepsis reports. The impact of sepsis-related deaths on all-cause hospital mortality is insufficiently ... -
Evaluation of immune responses in HIV infected patients with pleural tuberculosis by the QuantiFERON® TB-Gold interferon-gamma assay
Baba, Kamaldeen; Sørnes, Steinar; Hoosen, Anwar A.; Lekabe, Jacob M.; Mpe, Mathew J.; Langeland, Nina; Dyrhol-Riise, Anne Ma (Peer reviewed; Journal article, 2008-03-14)Background: Diagnosis of tuberculous (TB) pleuritis is difficult and better diagnostic tools are needed. New blood based interferon-gamma (IFN-γ) tests are promising, but sensitivity could be low in HIV positive patients. ... -
Experimental infection of healthy volunteers with enterotoxigenic Escherichia coli wild-type strain TW10598 in a hospital ward
Skrede, Steinar; Steinsland, Hans; Sommerfelt, Halvor; Aase, Audun; Brandtzaeg, Per; Langeland, Nina; Cox, Rebecca Jane; Sævik, Marianne; Wallevik, Marita; Skutlaberg, Dag Harald; Tellevik, Marit Gjerde; Sack, David A.; Nataro, James P.; Guttormsen, Anne Berit (Peer reviewed; Journal article, 2014-09-04)Background: Enterotoxigenic Escherichia coli (ETEC) is an important cause of childhood diarrhea in resource-limited regions. It is also an important cause of diarrhea in travellers to these areas. To evaluate the protective ... -
Fever in the tropics: aetiology and case-fatality - a prospective observational study in a tertiary care hospital in South India
Abrahamsen, Siri Kratter; Haugen, Cathrine Nødtvedt; Rupali, Priscilla; Mathai, Dilip; Langeland, Nina; Eide, Geir Egil; Mørch, Kristine (Peer reviewed; Journal article, 2013-07-30)Background: The objective of this study was to describe aetiology and case fatality of fever among inpatients in a tertiary care hospital in South India. Methods: This was an observational, prospective study conducted in ... -
Genetic diversity of circulating rotavirus strains in Tanzania prior to the introduction of vaccination
Moyo, Sabrina John; Blomberg, Bjørn; Hanevik, Kurt; Kommedal, Øyvind; Vainio, Kirsti; Maselle, Samwel Y.; Langeland, Nina (Peer reviewed; Journal article, 2014-05-20)Background: Tanzania currently rolls out vaccination against rotavirus-diarrhea, a major cause of child illness and death. As the vaccine covers a limited number of rotavirus variants, this study describes the molecular ...