Browsing Bergen Open Research Archive by Author "Larsen, Tor Ketil"
Now showing items 1-13 of 13
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Association between C-reactive protein levels and antipsychotic treatment during 12 months follow-up period after acute psychosis
Fathian, Farivar; Gjestad, Rolf; Kroken, Rune Andreas; Løberg, Else-Marie; Reitan, Solveig Merete Klæbo; Fleichhacker, W. Wolfgang; Rettenbacher, Maria; Larsen, Tor Ketil; Joa, Inge; Stabell, Lena Antonsen; Kjelby, Eirik; Sinkevicute, Igne; Alisauskiene, Renata; Steen, Vidar Martin; Johnsen, Erik (Journal article; Peer reviewed, 2022)Background A potential role of inflammatory pathways in the pathology of schizophrenia has been suggested for at least a subgroup of patients. Elevated levels of the inflammatory marker C-reactive protein (CRP) have been ... -
The association between cytokines and psychomotor speed in a spectrum of psychotic disorders: A longitudinal study
Larsen, Jeanette Brun; Reitan, Solveig Merete Klæbo; Løberg, Else-Marie; Rettenbacher, Maria; Bruserud, Øystein; Larsen, Tor Ketil; Anda, Liss Gøril; Bartz-Johannessen, Christoffer; Johnsen, Erik; Kroken, Rune Andreas (Journal article, 2021)Background In schizophrenia, impaired psychomotor speed is a common symptom predicting worse functional outcome. Inflammation causes changes in white matter integrity, which may lead to reduced psychomotor speed. Therefore, ... -
Childhood trauma, antipsychotic medication, and symptom remission in first-episode psychosis
Ottesen, Akiah; Hegelstad, Wenche; Joa, Inge; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Røssberg, Jan Ivar; Simonsen, Erik; Johannessen, Jan Olav; Larsen, Tor Ketil; Haahr, Ulrik H.; McGlashan, T.H.; Friis, Svein; Melle, Ingrid (Journal article; Peer reviewed, 2021)Background: To what extent psychotic symptoms in first-episode psychosis (FEP) with a history of childhood interpersonal trauma (CIT) are less responsive to antipsychotic medication is not known. In this longitudinal study, ... -
Depression trajectories and cytokines in schizophrenia spectrum disorders - A longitudinal observational study
Hoprekstad, Gunnhild Eldhuset; Kjelby, Eirik; Gjestad, Rolf; Fathian, Farivar; Larsen, Tor Ketil; Reitan, Solveig Klæbo; Rettenbacher, Maria; Torsvik, Anja; Skrede, Silje; Johnsen, Erik; Kroken, Rune Andreas (Journal article; Peer reviewed, 2023)Depression occurs frequently in all phases of schizophrenia spectrum disorders. Altered activity in the immune system is seen in both depression and schizophrenia. We aimed to uncover depressive trajectories in a sample ... -
Early substance use cessation improves cognition-10 years outcome in first-episode psychosis patients
Weibell, Melissa Anne E; Johannessen, Jan Olav; Auestad, Bjørn Henrik; Bramness, Jørgen Gustav; Brønnick, Kolbjørn Kallesten; Haahr, Ulrik; Joa, Inge; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Røssberg, Jan Ivar; Simonsen, Erik; Vaglum, Per; Stain, Helen J.; Friis, Svein; Hegelstad, Wenche (Peer reviewed; Journal article, 2019-07-12)Background: Cognitive impairment may be a risk factor for, as well as a consequence of, psychosis. Non-remitting symptoms, premorbid functioning, level of education, and socioeconomic background are known correlates. A ... -
"Everyone Needs a Friend Sometimes" - social predictors of long-term remission in first episode psychosis
Bjørnestad, Jone Ravndal; Joa, Inge; Larsen, Tor Ketil; Langeveld, Johannes H.; Davidson, Larry; Hegelstad, Wenche; Anda-Ågotnes, Liss Gøril; Veseth, Marius; Melle, Ingrid; Johannessen, Jan Olav; Brønnick, Kolbjørn Selvåg (Peer reviewed; Journal article, 2016-10-04)Background: Predictors of long-term symptomatic remission are crucial to the successful tailoring of treatment in first episode psychosis. There is lack of studies distinguishing the predictive effects of different social ... -
Geographical accessibility and duration of untreated psychosis: Distance as a determinant of treatment delay
Kvig, Erling Inge; Brinchmann, Beate; Moe, Cathrine Fredriksen; Nilssen, Steinar; Larsen, Tor Ketil; Sørgaard, Knut W. (Peer reviewed; Journal article, 2017-05-10)Background: The duration of untreated psychosis is determined by both patient and service related factors. Few studies have considered the geographical accessibility of services in relation to treatment delay in early ... -
Impact of childhood trauma on antipsychotic effectiveness in schizophrenia spectrum disorders: A prospective, pragmatic, semi-randomized trial
Mørkved, Nina; Johnsen, Erik; Kroken, Rune Andreas; Winje, Dagfinn; Larsen, Tor Ketil; Thimm, Jens; Rettenbacher, M.A.; Johannesen, C.A. Bartz; Løberg, Else-Marie (Journal article; Peer reviewed, 2022)Antipsychotic medications are generally effective in ameliorating psychotic symptoms in schizophrenia spectrum disorders (SSDs). Identifying predictors associated with poor treatment response is important for a personalized ... -
Negotiating the boundaries of psychosis: A qualitative studyof the service provider perspective on treatment delay incommunity mental health
Kvig, Erling Inge; Moe, Cathrine Fredriksen; Brinchmann, Beate; Larsen, Tor Ketil; Sørgaard, Knut W. (Peer reviewed; Journal article, 2017)Aim: Evidence shows that many patients are detected and treated late in their course of illness, and that substantial delay occurs even after entry to mental health services. Although several studies have examined the ... -
Obsessive-compulsive disorder (OCD) in patients with first- episode psychosis (FEP): A prospective study
Hagen, Kristen; Solem, Stian; Larsen, Tor Ketil; Joa, Inge; Kvale, Gerd; Hansen, Bjarne (Peer reviewed; Journal article, 2014) -
One-year outcome and adherence to pharmacological guidelines in first-episode schizophrenia: Results from a consecutive cohort study
Drosos, Petros; Brønnick, Kolbjørn Kallesten; Joa, Inge; Johannessen, Jan Olav; Johnsen, Erik; Kroken, Rune Andreas; Stain, Helen J.; Hegelstad, Wenche; Larsen, Tor Ketil (Journal article; Peer reviewed, 2020)Background Remission in schizophrenia is difficult to achieve. Antipsychotic drugs are critical in the treatment of schizophrenia. International guidelines for the pharmacological treatment of schizophrenia recommend a ... -
Psychiatric patients’ attitudes towards being hospitalized: a national multicentre study in Norway
Hustoft, Kjetil; Larsen, Tor Ketil; Brønnick, Kolbjørn Kallesten; Joa, Inge; Johannessen, Jan Olav; Ruud, Torleif (Journal article; Peer reviewed, 2022-11-21)Background: The aim of the study was to explore patients’ attitudes towards voluntary and involuntary hospitalization in Norway, and predictors for involuntary patients who wanted admission. Methods: A multi-centre study ... -
Psychotherapy in psychosis: Experiences of fully recovered service users
Bjørnestad, Jone Ravndal; Veseth, Marius; Davidson, Larry; Joa, Inge; Johannessen, Jan Olav; Larsen, Tor Ketil; Melle, Ingrid; Hegelstad, Wenche (Peer reviewed; Journal article, 2018-09-04)Background: Despite the evidence of the importance of including service users’ views on psychotherapy after psychosis, there is a paucity of research investigating impact on full recovery. Objectives: To explore what ...