Blar i Bergen Open Research Archive på forfatter "Leirgul, Elisabeth"
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Association Between Maternal Folic Acid Supplementation and Congenital Heart Defects in Offspring in Birth Cohorts From Denmark and Norway
Øyen, Nina; Olsen, Sjurdur Frodi; Basit, Saima; Leirgul, Elisabeth; Strøm, Marin; Carstensen, Lisbeth; Granström, Charlotta; Tell, Grethe S.; Magnus, Per; Vollset, Stein Emil; Wohlfart, Jan; Melbye, Mads (Peer reviewed; Journal article, 2019-03-19)Background: Evidence linking individual‐level maternal folic acid supplementation to offspring risk of congenital heart defects is lacking. We investigated whether folic acid supplementation in early pregnancy reduces ... -
Birth prevalence of congenital heart defects in Norway 1994-2009—A nationwide study
Leirgul, Elisabeth; Fomina, Tatiana; Brodwall, Kristoffer; Greve, Gottfried; Holmstrøm, Henrik; Vollset, Stein Emil; Tell, Grethe Seppola; Øyen, Nina (Peer reviewed; Journal article, 2014-08-10)Background The reasons for decreasing birth prevalence of congenital heart defects (CHDs) in several European countries and Canada are not fully understood. We present CHD prevalence among live births, stillbirths, and ... -
Intake of sucrose‑sweetened soft beverages during pregnancy and risk of congenital heart defects (CHD) in ofspring: a Norwegian pregnancy cohort study
Grønning Dale, Maria Teresa; Magnus, Per; Leirgul, Elisabeth; Holmstrøm, Henrik; Gjessing, Håkon K.; Brodwall, Kristoffer; Haugen, Margaretha; Stoltenberg, Camilla; Øyen, Nina (Peer reviewed; Journal article, 2019)Studies report increased risk of congenital heart defects (CHD) in the offspring of mothers with diabetes, where high blood glucose levels might confer the risk. We explored the association between intake of sucrose-sweetened ... -
Periconceptional Folic Acid Supplementation and Infant Risk of Congenital Heart Defects in Norway 1999-2009
Leirgul, Elisabeth; Gildestad, Trude; Nilsen, Roy Miodini; Fomina, Tatiana; Brodwall, Kristoffer; Greve, Gottfried; Vollset, Stein Emil; Holmstrøm, Henrik; Tell, Grethe Seppola; Øyen, Nina (Peer reviewed; Journal article, 2015-07-24)Background The birth prevalence of congenital heart defects (CHDs) has decreased in Canada and Europe. Recommended intake of folic acid in pregnancy is a suggestive risk-reducing factor for CHDs. We investigated the ... -
Prepregnancy diabetes and offspring risk of congenital heart disease - A nationwide cohort study
Øyen, Nina; Diaz, Lars J; Leirgul, Elisabeth; Boyd, Heather A; Priest, James; Mathiesen, Elisabeth R; Quertermous, Thomas; Wohlfahrt, Jan; Melbye, Mads (Peer reviewed; Journal article, 2016)Background—Maternal diabetes mellitus is associated with an increased risk of offspring congenital heart defects (CHD); however, the causal mechanism is poorly understood. We further investigated this association in a ...