Blar i Bergen Open Research Archive på forfatter "Leknes, Knut N."
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Cell seeding density is a critical determinant for copolymer scaffolds-induced bone regeneration
Yassin, Mohammed Ahmed; Leknes, Knut N.; Pedersen, Torbjørn Østvik; Xing, Zhe; Sun, Yang; Lie, Stein Atle; Finne-Wistrand, Anna; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2015-11)Constructs intended for bone tissue engineering (TE) are influenced by the initial cell seeding density. Therefore, the objective of this study was to determine the effect of bone marrow stromal stem cells (BMSCs) density ... -
Dental implant surface temperatures following double wavelength (2780/940 nm) laser irradiation in vitro
Fahlstedt, Peter; Bunæs, Dagmar; Lie, Stein Atle; Leknes, Knut N. (Journal article; Peer reviewed, 2020)Objective: To estimate the implant surface temperature at titanium dental implants during calibrated irradiation using double wavelength laser. Material and methods: A double wavelength laser, 2780 nm Er,Cr:YSGG and ... -
The effect of smoking on inflammatory and bone remodeling markers in gingival crevicular fluid and subgingival microbiota following periodontal therapy
Bunæs, Dagmar Fosså; Mustafa, Manal; Mohamed, Hasaan; Lie, Stein Atle; Leknes, Knut N. (Peer reviewed; Journal article, 2017)Background and Objective: Periodontal health is mediated by suppressing microorganisms inducing a local inflammatory host response. Smoking may impair this process. This study compares gingival crevicular fluid levels of ... -
Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs
Pedersen, Torbjørn Østvik; Blois, Anna L; Xing, Zhe; Xue, Ying; Sun, Yang; Finne-Wistrand, Anna; Akslen, Lars A.; Lorens, James B.; Leknes, Knut N.; Fristad, Inge; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2013-05-17)Introduction: A major determinant of the potential size of cell/scaffold constructs in tissue engineering is vascularization. The aims of this study were twofold: first to determine the in vitro angiogenic and osteogenic ... -
Mesenchymal stem cells induce endothelial cell quiescence and promote capillary formation
Pedersen, Torbjørn Østvik; Blois, Anna L; Xue, Ying; Xing, Zhe; Sun, Yang; Finne-Wistrand, Anna; Lorens, James B.; Fristad, Inge; Leknes, Knut N.; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2014-02-17)Introduction: Rapid establishment of functional blood vessels is a prerequisite for successful tissue engineering. During vascular development, endothelial cells (ECs) and perivascular cells assemble into a complex regulating ... -
Site-specific treatment outcome in smokers following 12 months of supportive periodontal therapy
Bunæs, Dagmar Fosså; Lie, Stein Atle; Åstrøm, Anne Nordrehaug; Mustafa, Kamal Babikeir Eln; Leknes, Knut N. (Peer reviewed; Journal article, 2016-12)Aim: To evaluate the effect of cigarette smoking on periodontal health at patient, tooth, and site levels following supportive therapy. Materials and Methods: Eighty chronic periodontitis patients, 40 smokers and 40 ...