• Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study 

      Peralta, Gabriela P.; Marcon, Alessandro; Carsin, Anne-Elie; Abramson, Michael J.; Accordini, Simone; Amaral, André F.S.; Antó, Josep Maria; Bowatte, Gayan; Burney, Peter; Corsico, Angelo; Demoly, Pascal; Dharmage, Shyamali C.; Forsberg, Bertil; Fuertes, Elaine; Garcia-Larsen, Vanessa; Gislason, Thorarinn; Gullón, José-Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Janson, Christer; Jõgi, Rain; Johannessen, Ane; Leynaert, Bénédicte; Rovira, Jesús Martínez-Moratalla; Nowak, Dennis; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Sigsgaard, Torben; Siroux, Valérie; Squillacioti, Giulia; Urrutia, Isabel; Weyler, Joost; Zock, Jan-Paul; Garcia-Aymerich, Judith (Journal article; Peer reviewed, 2020)
      Background Previous studies have reported an association between weight increase and excess lung function decline in young adults followed for short periods. We aimed to estimate lung function trajectories during adulthood ...
    • Body silhouettes as a tool to reflect obesity in the past 

      Lønnebotn, Marianne; Svanes, Cecilie; Igland, Jannicke; Franklin, Karl A.; Accordini, Simone; Benediktsdóttir, Bryndís; Bentohuami, Hayat; Blanco, José Antonio Gullón; Bono, Roberto; Corsico, Angelo; Demoly, Pascal; Dharmage, Shyamali; Dorado Arenas, Sandra; Garcia, Judith; Heinrich, Joachim; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Leynaert, Bénédicte; Martinez-Moratalla, Jesús; Nowak, Dennis; Pin, Isabelle; Raherison-Semjen, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Dratva, Julia; Gomez Real, Francisco (Peer reviewed; Journal article, 2018-04-25)
      Life course data on obesity may enrich the quality of epidemiologic studies analysing health consequences of obesity. However, achieving such data may require substantial resources. We investigated the use of body silhouettes ...
    • The coexistence of asthma and COPD: risk factors, clinical history and lung function trajectories 

      Marcon, Alessandro; Locatelli, Francesca; Dharmage, Shyamali C.; Svanes, Cecilie; Heinrich, Joachim; Leynaert, Bénédicte; Burney, Peter; Corsico, Angelo; Caliskan, Gulser; Calciano, Lucia; Gislason, Thorarinn; Janson, Christer; Jarvis, Deborah; Jõgi, Rain; Lytras, Theodore; Malinovschi, Andrei; Probst-Hensch, Nicole; Toren, Kjell; Casas, Lidia; Verlato, Giuseppe; Garcia-Aymerich, Judith; Accordini, Simone (Journal article; Peer reviewed, 2021)
      Patients with concomitant features of asthma and chronic obstructive pulmonary disease (COPD) have a heavy disease burden. Using data collected prospectively in the European Community Respiratory Health Survey, we ...
    • Cross-sectional study on exhaled nitric oxide in relation to upper airway inflammatory disorders with regard to asthma and perennial sensitization 

      Krantz, Christina; Accordini, Simone; Alving, Kjell; Corsico, Angelo G.; Demoly, Pascal; Ferreira, Diogenes S.; Forsberg, Bertil; Garcia-Aymerich, Judith; Gislason, Thorarinn; Heinrich, Joachim; Jõgi, Rain; Johannessen, Ane; Leynaert, Bénédicte; Marcon, Alessandro; Martínez-Moratalla Rovira, Jesús; Nerpin, Elisabet; Nowak, Dennis; Olin, Anna-Carin; Olivieri, Mario; Pereira-Vega, Antonio; Raherison-Semjen, Chantal; Real, Francisco Gomez; Sigsgaard, Torben; Squillacioti, Giulia; Janson, Christer; Malinovschi, Andrei (Journal article; Peer reviewed, 2022)
      Background: Fractional exhaled nitric oxide (FeNO) is a well-known marker of type-2 inflammation. FeNO is elevated in asthma and allergic rhinitis, with IgE sensitization as a major determinant. Objective: We aimed to ...
    • Describing the status of reproductive ageing simply and precisely: A reproductive ageing score based on three questions and validated with hormone levels 

      Triebner, Kai; Johannessen, Ane; Svanes, Cecilie; Leynaert, Bénédicte; Benediktsdóttir, Bryndís; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Lindberg, Eva; Moratalla, Jesús Martínez; Agirre, Nerea Muniozguren; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Skulstad, Svein Magne; Hustad, Steinar; Rodríguez, Francisco J.; Gomez Real, Francisco (Journal article; Peer reviewed, 2020)
      Objective Most women live to experience menopause and will spend 4–8 years transitioning from fertile age to full menstrual stop. Biologically, reproductive ageing is a continuous process, but by convention, it is defined ...
    • Determinants of fractional exhaled nitric oxide in healthy men and women from the European Community Respiratory Health Survey III 

      Nerpin, Elisabet; Olivieri, Mario; Gislason, Thorainn; Olin, Anna C.; Nielsen, Rune; Johannessen, Ane; Ferreira, Diogenes S.; Marcon, Alessandro; Cazzoletti, Lucia; Accordini, Simone; Pin, Isabelle; Corsico, Angelo; Demoly, Pascal; Weyler, Joost; Nowak, Dennis; Jõgi, Rain; Forsberg, Bertil; Zock, Jan P.; Sigsgaard, Torben; Heinric, Joachim; Bono, Roberto; Leynaert, Bénédicte; Jarvis, Deborah; Janson, Christer; Malinovschi, Anderi (Peer reviewed; Journal article, 2019)
      Introduction: The fractional exhaled nitric oxide (FENO ) is a marker for type 2 inflammation used in diagnostics and management of asthma. In order to use FENO as a reliable biomarker, it is important to investigate factors ...
    • Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS) 

      Triebner, Kai; Accordini, Simone; Calciano, Lucia; Johannessen, Ane; Benediktsdóttir, Bryndís; Bifulco, Ersilia; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Garcia-Aymerich, Judith; Gullón Blanco, José Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Debbie; Jõgi, Rain; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Svanes, Cecilie; Hustad, Simon Steinar; Leynaert, Bénédicte; Gomez Real, Francisco (Peer reviewed; Journal article, 2019)
      Objectives: Menopause involves hypoestrogenism, which is associated with numerous detrimental effects, including on respiratory health. Hormone replacement therapy (HRT) is often used to improve symptoms of menopause. The ...
    • Health-related quality of life as associated with asthma control, psychological status and insomnia 

      Rask-Andersen, Anna; Leander, Mai; Sundbom, Fredrik; Lampa, Erik; Oudin, Anna; Leynaert, Bénédicte; Svanes, Cecilie; Gislason, Thorarinn; Torén, Kjell; Janson, Christer (Journal article; Peer reviewed, 2022)
      Background: Asthma is associated not only with lower health-related quality of life (HRQL) but also with psychological health and insomnia. The aim of this study was to investigate associations between HRQL, asthma symptoms, ...
    • Low serum DHEA-S is associated with impaired lung function in women 

      Triebner, Kai; Pesce, Giancarlo; van der Plaat, Diana A.; Courbon, Dominique; Hustad, Steinar; Sigsgaard, Torben; Nowak, Dennis; Heinrich, Joachim; Antó, Jósep Maria; Dorado-Arenas, Sandra; Martínez-Moratalla, Jesús; Gullon-Blanco, Jose A.; Sánchez-Ramos, José L.; Rahérison, Chantal; Pin, Isabelle; Demoly, Pascal; Toren, Kjell; Forsberg, Bertil; Lindberg, Eva; Zemp, Elisabeth; Jogi, Rain; Probst-Hensch, Nicole; Dharmage, Shyamali C.; Jarvis, Debbie; Garcia-Aymerich, Judith; Marcon, Alessandro; Gómez-Real, Francisco; Leynaert, Bénédicte; Gislason, Thorarinn (Journal article; Peer reviewed, 2020)
      Background Emerging evidence suggests that androgens and estrogens have a role in respiratory health, but it is largely unknown whether levels of these hormones can affect lung function in adults from the general population. ...
    • Menopause as a predictor of new-onset asthma 

      Triebner, Kai; Johannessen, Ane; Puggini, Luca; Benediktsdottir, Bryndis; Bertelsen, Randi Jacobsen; Bifulco, Ersilia; Dharmage, Shyamali C.; Franklin, Karl A.; Gislason, Þórarinn; Holm, Mathias; Jarvis, Deborah; Leynaert, Bénédicte; Lindberg, Eva; Macsali, Ferenc; Malinovschi, Andrej; Norbäck, Dan; Omenaas, Ernst; Rodriguez, Francisco J; Saure, Eirunn Waatevik; Schlünssen, Vivi; Sigsgaard, Torben; Skorge, Trude Duelien; Wieslander, Gunilla; Zemp, Elisabeth; Svanes, Cecilie; Hustad, Simon Steinar; Gomez Real, Francisco (Peer reviewed; Journal article, 2015-01)
      Background: There is limited and conflicting evidence on the effect of menopause on asthma. Objectives: We sought to study whether the incidence of asthma and respiratory symptoms differ by menopausal status in a longitudinal ...
    • Physical activity and lung function—Cause or consequence? 

      Bédard, Annabelle; Carsin, Anne-Elie; Fuertes, Elaine; Accordini, Simone; Dharmage, Shyamali C.; Garcia-Larsen, Vanessa; Heinrich, Joachim; Janson, Christer; Johannessen, Ane; Leynaert, Bénédicte; Sánchez-Ramos, José Luis; Peralta, Gabriela P.; Pin, Isabelle; Squillacioti, Giulia; Weyler, Joost; Jarvis, Deborah; Garcia-Aymerich, Judith (Journal article; Peer reviewed, 2020)
      Concerns exist that the positive association of physical activity with better lung function, which has been suggested in previous longitudinal studies in smokers, is due to reverse causation. To investigate this, we applied ...
    • Residential surrounding greenspace and age at menopause: A 20-year European study (ECRHS) 

      Triebner, Kai; Markevych, Iana; Hustad, Simon Steinar; Benediktsdóttir, Bryndís; Forsberg, Bertil; Franklin, Karl A.; Gullón Blanco, José Antonio; Holm, Mathias; Jaquemin, Bénédicte; Jarvis, Debbie; Jõgi, Rain; Leynaert, Bénédicte; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Sánchez-Ramos, José Luis; Heinrich, Joachim; Gomez Real, Francisco; Dadvand, Payam (Peer reviewed; Journal article, 2019-08-19)
      Background Menopause is associated with a number of adverse health effects and its timing has been reported to be influenced by several lifestyle factors. Whether greenspace exposure is associated with age at menopause has ...
    • Restrictive spirometry pattern is associated with low physical activity levels. A population based international study 

      Carsin, Anne-Elie; Fuertes, Elaine; Schaffner, Emmanuel; Jarvis, Debbie; Antó, Josep M.; Heinrich, Joachim; Bellisario, Valeria; Svanes, Cecilie; Keidel, Dirk; Imboden, Medea; Weyler, Joost; Nowak, Dennis; Martínez-Moratalla, Jesús; Gullón, José-Antonio; Sánchez Ramos, José Luis; Caviezel, Seraina; Beckmeyer-Borowko, Anna; Raherison, Chantal; Pin, Isabelle; Demoly, Pascal; Cerveri, Isa; Accordini, Simone; Gislason, Þórarinn; Torén, Kjell; Forsberg, Bertil; Janson, Christer; Jõgi, Rain; Emtner, Margareta; Gomez Real, Francisco; Raza, Wasif; Leynaert, Bénédicte; Pascual, Silvia; Guerra, Stefano; Dharmage, Shyamali C.; Probst-Hensch, Nicole; Garcia-Aymerich, Judith (Peer reviewed; Journal article, 2019)
      Introduction: Restrictive spirometry pattern is an under-recognised disorder with a poor morbidity and mortality prognosis. We compared physical activity levels between adults with a restrictive spirometry pattern and with ...
    • Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey 

      Flexeder, Claudia; Zock, Jan-Paul; Jarvis, Deborah; Verlato, Giuseppe; Olivieri, Mario; Benke, Geza; Abramson, Michael J.; Sigsgaard, Torben; Svanes, Cecilie; Torén, Kjell; Nowak, Dennis; Jõgi, Rain; Martínez-Moratalla, Jesús; Demoly, Pascal; Janson, Christer; Gíslason, Þórarinn; Bono, Roberto; Holm, Mathias; Franklin, Karl A.; Garcia-Aymerich, Judith; Siroux, Valérie; Leynaert, Bénédicte; Dorado Arenas, Sandra; Corsico, Angelo Guido; Pereira-Vega, Antonio; Probst-Hensch, Nicole; Urrutia Landa, Isabel; Schulz, Holger; Heinrich, Joachim (Peer reviewed; Journal article, 2019-02-14)
      Background: Early life exposure to tobacco smoke has been extensively studied but the role of second-hand smoke (SHS) for new-onset respiratory symptoms and lung function decline in adulthood has not been widely investigated ...
    • Trends in smoking initiation in Europe over 40 years: A retrospective cohort study 

      Marcon, Alessandro; Pesce, Giancarlo; Calciano, Lucia; Bellisario, Valeria; Dharmage, Shyamali C.; Garcia-Aymerich, Judith; Gislasson, Thorarinn; Heinrich, Joachim; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Leynaert, Bénédicte; Matheson, Melanie C.; Pirina, Pietro; Svanes, Cecilie; Villani, Simona; Zuberbier, Torsten; Minelli, Cosetta; Accordini, Simone (Journal article; Peer reviewed, 2018)
      Background Tobacco consumption is the largest avoidable health risk. Understanding changes of smoking over time and across populations is crucial to implementing health policies. We evaluated trends in smoking initiation ...
    • Ultraviolet radiation as a predictor of sex hormone levels in postmenopausal women: A European multi-center study (ECRHS) 

      Triebner, Kai; Bifulco, Ersilia; Barrera-Gómez, Jose; Basagaña, Xavier; Benediktsdóttir, Bryndís; Forsberg, Bertil; Franklin, Karl A.; Garcia-Larsen, Vanessa; Leynaert, Bénédicte; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren-Agirre, Nerea; Pin, Isabelle; Raherison, Chantal; Pereira-Vega, Antonio; Schlünssen, Vivi; Valentin, Antonia; Hustad, Steinar; Real, Francisco Gomez; Dadvand, Payam (Journal article; Peer reviewed, 2021)
      Background Solar ultraviolet radiation (UVR) affects the body through pathways that exhibit positive as well as negative health effects such as immunoregulation and vitamin D production. Different vitamin D metabolites ...