Blar i Bergen Open Research Archive på forfatter "Li, Gang"

Viser treff 1-8 av 8

    • The dual role of glioma exosomal microRNAs: glioma eliminates tumor suppressor miR-1298-5p via exosomes to promote immunosuppressive effects of MDSCs 

      Qi, Yanhua; Jin, Chuandi; Qiu, Wei; Zhao, Rongrong; Wang, Shaobo; Li, Boyan; Zhang, Zongpu; Guo, Qindong; Zhang, Shouji; Gao, Zijie; Zhao, Shulin; Pan, Ziwen; Fan, Yang; chen, Zihang; Wang, Huizhi; Xu, Jianye; Deng, Lin; Ni, Shilei; Wang, Jian; Xue, Hao; Xue, Fuzhong; Li, Gang (Journal article; Peer reviewed, 2022)
      Clear evidence shows that tumors could secrete microRNAs (miRNAs) via exosomes to modulate the tumor microenvironment (TME). However, the mechanisms sorting specific miRNAs into exosomes are still unclear. In order to study ...

    • Industrial Dust Explosions. A Brief Review 

      Eckhoff, Rolf Kristian; Li, Gang (Journal article; Peer reviewed, 2021)
      This paper first addresses the question: what is a dust explosion? Afterwards, some specific issues are briefly reviewed: materials that can give dust explosions, factors influencing ignitability and explosibility of dust ...

    • Interfering with long non-coding RNA MIR22HG processing inhibits glioblastoma progression through suppression of Wnt/β-catenin signalling 

      Han, Mingzhi; Wang, Shuai; Fritah, Sabrina; Wang, Xu; Zhou, Wenjing; Yang, Ning; Ni, Shilei; Huang, Bin; Chen, Anjing; Li, Gang; Miletic, Hrvoje; Thorsen, Frits; Bjerkvig, Rolf; Li, Xingang; Wang, Jian (Peer reviewed; Journal article, 2020)
      Long non-coding RNAs play critical roles in tumour progression. Through analysis of publicly available genomic datasets, we found that MIR22HG, the host gene of microRNAs miR-22-3p and miR-22-5p, is ranked among the most ...

    • Melatonin enhances proliferation and modulates differentiation of neural stem cells via autophagy in hyperglycemia 

      Li, Haoyuan; Zhang, Yanming; Liu, Shangming; Li, Fengpeng; Wang, Benlin; Wang, Jianjie; Cao, Lanfang; Xia, Tongliang; Yao, Qingyu; Chen, Haijun; Zhang, Yulin; Zhu, Xiaodong; Li, Yang; Li, Gang; Wang, Jian; Li, Xingang; Ni, Shilei (Journal article; Peer reviewed, 2019-01)
      Dysfunction of neural stem cells (NSCs) has been linked to fetal neuropathy, one of the most devastating complications of gestational diabetes. Several studies have demonstrated that melatonin (Mel) exerted neuroprotective ...

    • SPI1-induced downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner 

      Zhang, Shouji; Zhao, Shulin; Qi, Yanhua; Li, Boyan; Wang, Huizhi; Pan, Ziwen; Xue, Hao; Jin, Chuandi; Qiu, Wei; Chen, Zihang; Guo, Qindong; Fan, Yang; Xu, Jianye; Gao, Zijie; Wang, Shaobo; Guo, Xing; Deng, Lin; Ni, Shilei; Xue, Fuzhong; Wang, Jian; Zhao, Rongrong; Li, Gang (Journal article; Peer reviewed, 2022)
      As one of the most common post-transcriptional modifications of mRNAs and noncoding RNAs, N6-methyladenosine (m6A) modification regulates almost every aspect of RNA metabolism. Evidence indicates that dysregulation of m6A ...

    • Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention 

      Wang, Xu; Han, Mingzhi; Wang, Shuai; Sun, Yanfei; Zhao, Wenbo; Xue, Zhiyi; Liang, Xiangjun; Huang, Bin; Li, Gang; Chen, Anjing; Li, Xingang; Wang, Jian (Journal article; Peer reviewed, 2022)
      Background: Splicing factors are essential for nascent pre-mRNA processing and critical in cancer progression, suggesting that proteins with splicing functions represent potential molecular targets for cancer therapy. Here, ...

    • Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma 

      Han, Mingzhi; Wang, Shuai; Yang, Ning; Wang, Xu; Zhao, Wenbo; Sdik Saed, Halala; Daubon, Thomas; Huang, Bin; Chen, Anjing; Li, Gang; Miletic, Hrvoje; Thorsen, Frits; Bjerkvig, Rolf; Li, Xingang; Wang, Jian (Peer reviewed; Journal article, 2019-11-28)
      Dysregulated cholesterol metabolism is a hallmark of many cancers, including glioblastoma (GBM), but its role in disease progression is not well understood. Here, we identified cholesterol 24‐hydroxylase (CYP46A1), a ...

    • TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα 

      Ji, Jianxiong; Ding, Kaikai; Luo, Tao; Zhang, Xin; Chen, Anjing; Zhang, Di; Li, Gang; Thorsen, Frits; Huang, Bin; Li, Xingang; Wang, Jian (Journal article; Peer reviewed, 2021)
      NF-κB signaling plays a critical role in tumor growth and treatment resistance in GBM as in many other cancers. However, the molecular mechanisms underlying high, constitutive NF-κB activity in GBM remains to be elucidated. ...