Browsing Bergen Open Research Archive by Author "Li, Wenjie"
Now showing items 1-5 of 5
-
BCL2L13 promotes mitophagy through DNM1L-mediated mitochondrial fission in glioblastoma
Wang, Jiwei; Chen, Anbin; Xue, Zhiwei; Liu, Junzhi; He, Ying; Liu, Guowei; Zhao, Zhimin; Li, Wenjie; Zhang, Qing; Chen, Anjing; Wang, Jian; Li, Xingang; Wang, Xinyu; Huang, Bin (Journal article; Peer reviewed, 2023)There is an urgent need for novel diagnostic and therapeutic strategies for patients with Glioblastoma multiforme (GBM). Previous studies have shown that BCL2 like 13 (BCL2L13) is a member of the BCL2 family regulating ... -
The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma
Kong, Yang; Feng, Zichao; Chen, Anjing; Qi, Qichao; Han, Mingzhi; Wang, Shuai; Zhang, Yulin; Zhang, Xin; Yang, Ning; Wang, Jiwei; Huang, Bin; Zhang, Qing; Xiang, Guo; Li, Wenjie; Zhang, Di; Wang, Jian; Li, Xingang (Peer reviewed; Journal article, 2019-09-27)Galangin (GG), a flavonoid, elicits a potent antitumor activity in diverse cancers. Here, we evaluated the efficacy of GG in the treatment of human glioblastoma multiforme (GBM) and investigated the molecular basis for its ... -
Reduced expression of proteolipid protein 2 increases ER stress-induced apoptosis and autophagy in glioblastoma.
Feng, Zichao; Zhou, Wenjing; Wang, Jiwei; Qi, Qichao; Han, Mingzhi; Kong, Yang; Hu, Yaotian; Zhang, Yulin; Chen, Anbin; Huang, Bin; Zhang, Di; Li, Wenjie; Zhang, Qing; Bjerkvig, Rolf; Wang, Jian; Thorsen, Frits; Li, Xingang (Peer reviewed; Journal article, 2019-11-28)Proteolipid protein 2 (PLP2) is an integral ion channel membrane protein of the endoplasmic reticulum. The protein has been shown to be highly expressed in many cancer types, but its importance in glioma progression is ... -
Thiabendazole Inhibits Glioblastoma Cell Proliferation and Invasion Targeting Mini-chromosome Maintenance Protein 2
Hu, Yaotian; Zhou, Wenjing; Xue, Zhiyi; Liu, Xuemeng; Feng, Zichao; Zhang, Yulin; Liu, Xiaofei; Li, Wenjie; Zhang, Qing; Chen, Anjing; Huang, Bin; Wang, Jian (Journal article; Peer reviewed, 2022)Thiabendazole (TBZ), approved by the US Food and Drug Administration (FDA) for human oral use, elicits a potential anticancer activity on cancer cells in vitro and in animal models. Here, we evaluated the efficacy of TBZ ... -
TRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 protein
Yang, Xu; Zhang, Yan; Xue, Zhiwei; Hu, Yaotian; Zhou, Wenjing; Xue, Zhiyi; Liu, Xuemeng; Liu, Guowei; Li, Wenjie; Liu, Xiaofei; Li, Xingang; Han, Mingzhi; Wang, Jian (Journal article; Peer reviewed, 2022)Background The tripartite motif (TRIM) family of proteins plays a key role in the developmental growth and therapeutic resistance of many tumors. However, the regulatory mechanisms and biological functions of TRIM proteins ...