Browsing Bergen Open Research Archive by Author "Lillesand, Melinda"
Now showing items 1-3 of 3
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Digital Image Analysis of the Proliferation Markers Ki67 and Phosphohistone H3 in Gastroenteropancreatic Neuroendocrine Neoplasms: Accuracy of Grading Compared with Routine Manual Hot Spot Evaluation of the Ki67 Index
Lea, Dordi; Gudlaugsson, Einar G.; Skaland, Ivar; Lillesand, Melinda; Søreide, Kjetil; Søreide, Jon A. (Journal article; Peer reviewed, 2021)Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are rare epithelial neoplasms. Grading is based on mitotic activity or the percentage of Ki67-positive cells in a hot spot. Routine methods have poor intraobserver ... -
High-Grade Cervical Intraepithelial Neoplasia (CIN) Associates with Increased Proliferation and Attenuated Immune Signaling
Øvestad, Irene Tveiterås; Engesæter, Birgit Øvstebø; Halle, Mari Kyllesø; Akbari, Saleha; Bicskei, Beatrix; Lapin, Morten; Austdal, Marie; Janssen, Emiel; Krakstad, Camilla; Lillesand, Melinda; Nordhus, Marit; Munk, Ane Cecilie Dæhli; Gudlaugsson, Einar (Journal article; Peer reviewed, 2021)Implementation of high-risk human papilloma virus (HPV) screening and the increasing proportion of HPV vaccinated women in the screening program will reduce the percentage of HPV positive women with oncogenic potential. ... -
A template to quantify the location and density of CD3 + and CD8 + tumor-infiltrating lymphocytes in colon cancer by digital pathology on whole slides for an objective, standardized immune score assessment
Lea, Dordi; Watson, Martin Matthew Christian; Skaland, Ivar; Hagland, Hanne Røland; Lillesand, Melinda; Gudlaugsson, Einar; Søreide, Kjetil (Journal article; Peer reviewed, 2021)Background: In colon cancer, the location and density of tumor-infiltrating lymphocytes (TILs) can classify patients into low and high-risk groups for prognostication. While a commercially available ‘Immunoscore®’ exists, ...