Blar i Bergen Open Research Archive på forfatter "Liu, Hengshuo"
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Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis
Martínez-Nieto, Guillermo A.; Teppo, Hanna-Riikka; Petrelius, Noora; Izzi, Valerio; Devarajan, Raman; Petäistö, Tiina; Liu, Hengshuo; Kim, Kris S.; Karppinen, Sanna-Maria; Ruotsalainen, Heli; Koivunen, Jarkko; Mäki, Joni M.; Walker, Gilbert C.; Pihlajaniemi, Taina; Gullberg, Elon Donald; Heljasvaara, Ritva Leena (Journal article; Peer reviewed, 2022)Integrin α11β1 is a collagen-binding integrin that is needed to induce and maintain the myofibroblast phenotype in fibrotic tissues and during wound healing. The expression of the α11 is upregulated in cancer-associated ... -
α11β1 integrin is induced in a subset of cancer- associated fibroblasts in desmoplastic tumor stroma and mediates in vitro cell migration
Zeltz, Cedric; Alam, Jahedul; Liu, Hengshuo; Erusappan, Pugazendhi M; Hoschuetzky, Heinz; Molven, Anders; Parajuli, Himalaya; Cukierman, Edna; Costea, Daniela Elena; Lu, Ning; Gullberg, Donald (Peer reviewed; Journal article, 2019-06-01)Integrin α11β1 is a collagen receptor that has been reported to be overexpressed in the stroma of non-small cell lung cancer (NSCLC) and of head and neck squamous cell carcinoma (HNSCC). In the current study, we further ...