Browsing Bergen Open Research Archive by Author "Liu, Xiaofei"
Now showing items 1-4 of 4
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Identification of immune-related genes contributing to the development of glioblastoma using weighted gene co-expression network analysis
Kong, Yang; Feng, Zichao; Zhang, Yulin; Liu, Xiaofei; Ma, Yuan; Zhao, Zhimin; Huang, Bin; Chen, An-Jing; Zhang, Di; Thorsen, Frits; Wang, Jian; Yang, Ning; Li, Xingang (Journal article; Peer reviewed, 2020)Background: The tumor microenvironment (TME) of human glioblastoma (GBM) exhibits considerable immune cell infiltration, and such cell types have been shown to be widely involved in the development of GBM. Here, weighted ... -
Thiabendazole Inhibits Glioblastoma Cell Proliferation and Invasion Targeting Mini-chromosome Maintenance Protein 2
Hu, Yaotian; Zhou, Wenjing; Xue, Zhiyi; Liu, Xuemeng; Feng, Zichao; Zhang, Yulin; Liu, Xiaofei; Li, Wenjie; Zhang, Qing; Chen, Anjing; Huang, Bin; Wang, Jian (Journal article; Peer reviewed, 2022)Thiabendazole (TBZ), approved by the US Food and Drug Administration (FDA) for human oral use, elicits a potential anticancer activity on cancer cells in vitro and in animal models. Here, we evaluated the efficacy of TBZ ... -
TRIM56 promotes malignant progression of glioblastoma by stabilizing cIAP1 protein
Yang, Xu; Zhang, Yan; Xue, Zhiwei; Hu, Yaotian; Zhou, Wenjing; Xue, Zhiyi; Liu, Xuemeng; Liu, Guowei; Li, Wenjie; Liu, Xiaofei; Li, Xingang; Han, Mingzhi; Wang, Jian (Journal article; Peer reviewed, 2022)Background The tripartite motif (TRIM) family of proteins plays a key role in the developmental growth and therapeutic resistance of many tumors. However, the regulatory mechanisms and biological functions of TRIM proteins ... -
Valtrate, an iridoid compound in Valeriana, elicits anti-glioblastoma activity through inhibition of the PDGFRA/MEK/ERK signaling pathway
Liu, Xuemeng; Hu, Yaotian; Xue, Zhiyi; Zhang, Xun; Liu, Xiaofei; Liu, Guowei; Wen, Muzi; Chen, Anjing; Huang, Bin; Li, Xingang; Yang, Ning; Wang, Jian (Journal article; Peer reviewed, 2023)Background Valtrate, a natural compound isolated from the root of Valeriana, exhibits antitumor activity in many cancers through different mechanisms. However, its efficacy for the treatment of glioblastoma (GBM), a ...