Browsing Bergen Open Research Archive by Author "Lopez Moreno, Andrea Johana"
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Atomic view into plasmodium actin polymerization, ATP hydrolysis, and fragmentation
Kumpula, Esa-Pekka; Lopez Moreno, Andrea Johana; Tajedin, Leila; Han, Huijong; Kursula, Inari (Peer reviewed; Journal article, 2019)Plasmodium actins form very short filaments and have a noncanonical link between ATP hydrolysis and polymerization. Long filaments are detrimental to the parasites, but the structural factors constraining Plasmodium ... -
Structural and biochemical characterization of Malaria parasites
Lopez Moreno, Andrea Johana (Doctoral thesis, 2021-09-17)The Apicomplexa phylum includes more than 6000 species, and some of them are pathogens of humans and animals of socio-economic importance. The most representative parasites are Plasmodium spp. and Toxoplasma gondii. ... -
Structure and function of Plasmodium actin II in the parasite mosquito stages
Lopez Moreno, Andrea Johana; Andreadaki, Maria; Vahokoski, Juha; Deligianni, Elena; Calder, Lesley J.; Camerini, Serena; Freitag, Anika; Bergmann, Ulrich; Rosenthal, Peter B.; Sidén-Kiamos, Inga; Kursula, Inari Talvikki (Journal article; Peer reviewed, 2023)Actins are filament-forming, highly-conserved proteins in eukaryotes. They are involved in essential processes in the cytoplasm and also have nuclear functions. Malaria parasites (Plasmodium spp.) have two actin isoforms ...