Browsing Bergen Open Research Archive by Author "Lorentzen, Åslaug Rudjord"
Now showing items 1-15 of 15
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Assessment of cognitive function, structural brain changes and fatigue 6 months after treatment of neuroborreliosis
Andreassen, Silje; Lindland, Elisabeth Margrete Stokke; Beyer, Mona K.; Solheim, Anne Marit; Ljøstad, Unn; Mygland, Åse Daasvand; Lorentzen, Åslaug Rudjord; Reiso, Harald; Bjuland, Knut Jørgen; Pripp, Are Hugo; Harbo, Hanne-Cathrin Flinstad; Løhaugen, Gro; Eikeland, Randi (Journal article; Peer reviewed, 2022)Background Complete recovery after adequately treated neuroborreliosis is common, but studies report that some patients experience persistent symptoms like self-reported cognitive problems and fatigue. Persisting symptoms ... -
Autologous hematopoietic stem cell transplantation for multiple sclerosis: Long-term follow-up data from Norway
Kvistad, Christopher Elnan; Lehmann, Anne Kristine; Stokke, Silje Agnethe; Holmøy, Trygve; Lorentzen, Åslaug Rudjord; Trovik, Linn; Kristoffersen, Einar Klæboe; Bø, Lars; Torkildsen, Øivind (Journal article; Peer reviewed, 2024)Background: Autologous hematopoietic stem cell transplantation (HSCT) is a potent treatment option for patients with aggressive relapsing-remitting multiple sclerosis (RRMS). Objective: To evaluate long-term outcomes ... -
Clinical characteristics and factors affecting disease severity in hospitalized tick-borne encephalitis patients in Norway from 2018 to 2022
Skudal, Hilde Kristin; Lorentzen, Åslaug Rudjord; Stenstad, Tore; Paulsen, Else Quist; Egeland, Jens; Fevang, Børre; Jaioun, Keson; Hansen, Bjørn Åsheim; Solheim, Anne Marit; Tveten, Yngvar; Veje, Malin; Eikeland, Randi; Kersten, Hege (Journal article; Peer reviewed, 2024)Purpose To describe the clinical characteristics and factors associated with disease severity in a Norwegian cohort of hospitalized patients with tick-borne encephalitis (TBE). Methods This observational multicenter study ... -
Cognitive function in patients with neuroborreliosis: A prospective cohort study from the acute phase to 12 months post treatment
Andreassen, Silje; Solheim, Anne Marit; Ljøstad, Unn; Mygland, Åse Daasvand; Lorentzen, Åslaug Rudjord; Reiso, Harald; Beyer, Mona Kristiansen; Harbo, Hanne-Cathrin Flinstad; Løhaugen, Gro; Eikeland, Randi (Journal article; Peer reviewed, 2022)Background Long-term cognitive problems after neuroborreliosis treatment remain a subject of debate. We have previously shown that cognitive problems are not present in the acute phase of neuroborreliosis, although fatigue ... -
Dynamic contrast-enhanced MRI shows altered blood–brain barrier function of deep gray matter structures in neuroborreliosis: a case–control study
Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Andreassen, Silje; Bugge, Robin Antony Birkeland; Eikeland, Randi; Reiso, Harald; Lorentzen, Åslaug Rudjord; Harbo, Hanne-Cathrin Flinstad; Beyer, Mona Kristiansen; Bjørnerud, Atle (Journal article; Peer reviewed, 2023)Background Main aim was assessment of regional blood–brain barrier (BBB) function by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in patients with neuroborreliosis. Secondary aim was to study the correlation ... -
Enhancement of cranial nerves in Lyme neuroborreliosis: incidence and correlation with clinical symptoms and prognosis
Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Dareez, Muhammad Nazeer; Eikeland, Randi; Ljøstad, Unn; Mygland, Åse Daasvand; Reiso, Harald; Lorentzen, Åslaug Rudjord; Harbo, Hanne; Beyer, Mona Kristiansen (Journal article; Peer reviewed, 2022)Purpose Symptoms of cranial neuritis are a common presentation of Lyme neuroborreliosis (LNB). Imaging studies are scarce and report contradictory low prevalence of enhancement compared to clinical studies of cranial ... -
Human seroprevalence of antibodies to tick-borne microbes in southern Norway
Thortveit, Erik Thomas; Aase, Audun; Petersen, Lizette Balle; Lorentzen, Åslaug Rudjord; Mygland, Åse; Ljøstad, Unn (Journal article; Peer reviewed, 2020)The tick Ixodes ricinus is widespread along the coastline of southern Norway, but data on human exposure to tick-borne microbes are scarce. We aimed to assess the seroprevalence of IgG antibodies to various tick-borne ... -
Humoral immunity to SARS-CoV-2 mRNA vaccination in multiple sclerosis: the relevance of time since last rituximab infusion and first experience from sporadic revaccinations
König, Marton; Lorentzen, Åslaug Rudjord; Torgauten, Hilde Marie; Tran, The Trung; Schikora-Rustad, Stine; Vaage, Eline Benno; Mygland, Åse Daasvand; Wergeland, Stig; Aarseth, Jan Harald; Aaberge, Ingeborg Sundsvalen; Torkildsen, Øivind; Holmøy, Trygve; Berge, Tone; Myhr, Kjell-Morten; Harbo, Hanne-Cathrin Flinstad; Andersen, Jan Terje; Munthe, Ludvig Andre; Søraas, Arne Vasli; Celius, Elisabeth Gulowsen; Vaage, John T.; Lund-Johansen, Fridtjof; Nygaard, Gro Owren (Journal article; Peer reviewed, 2021)Introduction The effect of disease-modifying therapies (DMT) on vaccine responses is largely unknown. Understanding the development of protective immunity is of paramount importance to fight the COVID-19 pandemic. Objective ... -
Imaging in Lyme neuroborreliosis
Lindland, Elisabeth Margrete Stokke; Solheim, Anne Marit; Andreassen, Silje; Paulsen, Else Quist; Eikeland, Randi; Ljøstad, Unn; Mygland, Åse; Elsais, Ahmed; Nygaard, Gro Owren; Lorentzen, Åslaug Rudjord; Harbo, Hanne Flinstad; Beyer, Mona K. (Peer reviewed; Journal article, 2018-10)Lyme neuroborreliosis (LNB) is a tick-borne spirochetal infection with a broad spectrum of imaging pathology. For individuals who live in or have travelled to areas where ticks reside, LNB should be considered among ... -
Patient-reported outcome after treatment for definite Lyme neuroborreliosis
Eikeland, Randi; Ljøstad, Unn; Helgeland, Geir; Sand, Geir; Flemmen, Heidi Øyen; Bø, Margrete Halvorsen; Nordaa, Ludmila; Owe, Jone Furulund; Mygland, Åse; Lorentzen, Åslaug Rudjord (Journal article; Peer reviewed, 2020)Objective To chart patient‐reported outcome measures (PROMs) in Norwegian patients treated for definite neuroborreliosis (NB). Material and Methods Adult patients treated for definite NB 1–10 years earlier supplied ... -
Perinatal Depression and Anxiety in Women with Multiple Sclerosis: A Population-Based Cohort Study
Eid, Karine; Torkildsen, Øivind Fredvik Grytten; Aarseth, Jan Harald; Flemmen, Heidi Øyen; Holmøy, Trygve; Lorentzen, Åslaug Rudjord; Myhr, Kjell-Morten; Riise, Trond; Simonsen, Cecilia Smith; Torkildsen, Cecilie Fredvik; Wergeland, Stig; Willumsen, Johannes Sverre; Øksendal, Nina; Gilhus, Nils Erik; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2021)Objective: To assess the occurrence of perinatal depression and anxiety in women before and after diagnosis of multiple sclerosis (MS). Methods: 114,629 pregnant women were included in the Norwegian Mother, Father and Child ... -
Selective intrathecal enrichment of G1m1-positive B cells in multiple sclerosis
Lossius, Peter Andreas Vold; Tomescu-Baciu, Alina; Holmøy, Trygve; Vedeler, Christian A.; Røsjø, Egil Rørvik; Lorentzen, Åslaug Rudjord; Casetta, Ilaria; Vartdal, Frode (Peer reviewed; Journal article, 2017-10)Immunoglobulin gamma (IgG) heavy chain genes are associated with susceptibility to multiple sclerosis (MS) and IgG levels in the cerebrospinal fluid (CSF). However, how these variants are implicated in disease mechanisms ... -
Serum neurofilament light chain associates with symptom burden in Lyme neuroborreliosis patients: a longitudinal cohort study from Norway
Skarstein, Ingerid; Ulvestad, Elling; Solheim, Anne Marit; Vedeler, Christian; Ljøstad, Unn; Mygland, Åse; Eikeland, Randi; Reiso, Harald; Lorentzen, Åslaug Rudjord; Bos-Haugen, Steffan Daniel (Journal article; Peer reviewed, 2024)Objectives: Serum neurofilament light chain (sNfL), an indicator of neuronal damage, is increasingly recognized as a potential biomarker for disease activity in neurodegenerative disorders. In this study, we wanted to ... -
Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, noninferiority, double-blinded, randomised and placebocontrolled trial
Solheim, Anne Marit; Lorentzen, Åslaug Rudjord; Dahlberg, Audun Olav; Flemmen, Heidi Øyen; Brune, Synne; Forselv, Kristine Johanne Nordstrøm; Pripp, Are Hugo; Bø, Margrete Halvorsen; Eikeland, Randi; Reiso, Harald; Mygland, Åse Daasvand; Ljøstad, Unn (Journal article; Peer reviewed, 2022)Background There is limited evidence regarding optimal duration of antibiotic treatment in neuroborreliosis. We aimed to compare efficacy and safety of oral doxycycline for 2 and 6 weeks in European Lyme neuroborreliosis ... -
Subjective health complaints and exposure to tick-borne infections in southern Norway
Thortveit, Erik Thomas; Aase, Audun; Petersen, Lizette Balle; Lorentzen, Åslaug Rudjord; Mygland, Åse; Ljøstad, Unn (Journal article; Peer reviewed, 2020)Objectives: Whether tick‐borne infections can cause chronic subjective health complaints is heavily debated. If such a causal connection exists, one would expect to find more health complaints among individuals exposed to ...