Blar i Bergen Open Research Archive på forfatter "Ludl, Adriaan-Alexander"
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Comparison between instrumental variable and mediation-based methods for reconstructing causal gene networks in yeast
Ludl, Adriaan-Alexander; Michoel, Tom Luk Robert (Journal article; Peer reviewed, 2021)Causal gene networks model the flow of information within a cell. Reconstructing causal networks from omics data is challenging because correlation does not imply causation. When genomics and transcriptomics data from a ... -
Development of two-photon polymerised scaffolds for optical interrogation and neurite guidance of human iPSC-derived cortical neuronal networks
Crowe, J. A.; El-Tamer, A.; Nagel, D.; Koroleva, A. V.; Madrid-Wolff, J.; Olarte, O. E.; Sokolovsky, S.; Estevez-Priego, E.; Ludl, Adriaan-Alexander; Soriano, J.; Loza-Alvarez, P.; Chichkov, B. N.; Hill, E. J.; Parri, H. R.; Rafailov, E. U. (Journal article; Peer reviewed, 2020)Recent progress in the field of human induced pluripotent stem cells (iPSCs) has led to the efficient production of human neuronal cell models for in vitro study. This has the potential to enable the understanding of live ... -
Impact of physical obstacles on the structural and effective connectivity of in silico neuronal circuits
Ludl, Adriaan-Alexander; Soriano, Jordi (Journal article; Peer reviewed, 2020)Scaffolds and patterned substrates are among the most successful strategies to dictate the connectivity between neurons in culture. Here, we used numerical simulations to investigate the capacity of physical obstacles ... -
In Vitro Development of Human iPSC-Derived Functional Neuronal Networks on Laser-Fabricated 3D Scaffolds
Koroleva, Anastasia; Deiwick, Andrea; El-Tamer, Ayman; Koch, Lothar; Shi, Yichen; Estévez-Priego, Estefanía; Ludl, Adriaan-Alexander; Soriano, Jordi; Guseva, Daria; Ponimaskin, Evgeni; Chichkov, Boris (Journal article; Peer reviewed, 2021)Neural progenitor cells generated from human induced pluripotent stem cells (hiPSCs) are the forefront of ″brain-on-chip″ investigations. Viable and functional hiPSC-derived neuronal networks are shaping powerful in vitro ...