Blar i Bergen Open Research Archive på forfatter "Lund-Johansen, Fridtjof"
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Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID‑19 (Bari‑SolidAct): a randomised, double‑blind, placebo‑controlled phase 3 trial
Trøseid, Marius; Arribas, José R.; Assoumou, Lambert; Holten, Aleksander Rygh; Poissy, Julien; Terzic, Vida; Mazzaferri, Fulvia; Baño, Jesús Rodríguez; Eustace, Joe; Hites, Maya; Joannidis, Michael; Paiva, José-Artur; Reuter, Jean; Püntmann, Isabel; Patrick-Brown, Thale Dawn; Westerheim, Elin; Nezvalova-Henriksen, Katerina; Beniguel, Lydie; Dahl, Tuva Børresdatter; Bouscambert, Maude; Halanova, Monika; Péterfi, Zoltán; Tsiodras, Sotirios; Rezek, Michael; Briel, Matthias; Ünal, Serhat; Schlegel, Martin; Ader, Florence; Lacombe, Karine; Amdal, Cecilie Delphin; Rodrigues, Serge; Tonby, Kristian; Gaudet, Alexandre; Heggelund, Lars; Mootien, Joy; Johannessen, Asgeir; Møller, Jannicke Horjen; Pollan, Beatriz Diaz; Tveita, Anders Aune; Kildal, Anders Benjamin; Richard, Jean-Christophe; Dalgard, Olav; Simensen, Victoria Charlotte; Baldé, Aliou; de Gastines, Lucie; del Álamo, Marta; Aydin, Burç; Lund-Johansen, Fridtjof; Trabaud, Mary-Anne; Diallo, Alpha; Halvorsen, Bente; Røttingen, John-Arne; Tacconelli, Evelina; Yazdanpanah, Yazdan; Olsen, Inge Christoffer; Costagliola, Dominique; Study Group, EU-SolidAct (Journal article; Peer reviewed, 2023)Background Baricitinib has shown efficacy in hospitalized patients with COVID-19, but no placebo-controlled trials have focused specifically on severe/critical COVID, including vaccinated participants. Methods Bari-SolidAct ... -
EWAS of post-COVID-19 patients shows methylation differences in the immune-response associated gene, IFI44L, three months after COVID-19 infection
Lee, Yunsung; Riskedal, Espen; Kalleberg, Karl Trygve; Istre, Mette Stausland; Lind, Andreas; Lund-Johansen, Fridtjof; Reiakvam, Olaug Marie; Søraas, Arne Vasli; Harris, Jennifer Ruth; Dahl, John Arne; Lund Hadley, Cathrine; Jugessur, Astanand (Journal article; Peer reviewed, 2022)Although substantial progress has been made in managing COVID-19, it is still difficult to predict a patient’s prognosis. We explored the epigenetic signatures of COVID-19 in peripheral blood using data from an ongoing ... -
Humoral immunity to SARS-CoV-2 mRNA vaccination in multiple sclerosis: the relevance of time since last rituximab infusion and first experience from sporadic revaccinations
König, Marton; Lorentzen, Åslaug Rudjord; Torgauten, Hilde Marie; Tran, The Trung; Schikora-Rustad, Stine; Vaage, Eline Benno; Mygland, Åse Daasvand; Wergeland, Stig; Aarseth, Jan Harald; Aaberge, Ingeborg Sundsvalen; Torkildsen, Øivind; Holmøy, Trygve; Berge, Tone; Myhr, Kjell-Morten; Harbo, Hanne-Cathrin Flinstad; Andersen, Jan Terje; Munthe, Ludvig Andre; Søraas, Arne Vasli; Celius, Elisabeth Gulowsen; Vaage, John T.; Lund-Johansen, Fridtjof; Nygaard, Gro Owren (Journal article; Peer reviewed, 2021)Introduction The effect of disease-modifying therapies (DMT) on vaccine responses is largely unknown. Understanding the development of protective immunity is of paramount importance to fight the COVID-19 pandemic. Objective ... -
Low Immunization Rate in Kidney Transplant Recipients Also After Dose 2 of the BNT162b2 Vaccine: Continue to Keep Your Guard up!
Midtvedt, Karsten; Tran, Trung; Parker, Krystina; Marti, Hans Peter; Stenehjem, Aud Eldrid; Gøransson, Lasse Gunnar; Soldal, Kari Mørkve; Madsen, Camilla; Smedbråten, Julia; Vaage, Eline Benno; Lund-Johansen, Fridtjof; Åsberg, Anders (Journal article, 2021) -
Persistent pulmonary pathology after COVID‑19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase‑9
Lerum, Tøri Vigeland; Maltzahn, Niklas; Aukrust, Pål; Trøseid, Marius; Nezvalova-Henriksen, Katerina; Kåsine, Trine; Dyrhol-Riise, Anne Ma; Stiksrud, Birgitte; Haugli, Mette; Blomberg, Bjørn; Kittang, Bård Reiakvam; Johannessen, Asgeir; Hannula, Raisa; Aballi, Saad; Kildal, Anders Benjamin; Eiken, Ragnhild; Dahl, Tuva Børresdatter; Lund-Johansen, Fridtjof; Müller, Fredrik; Rivero, Jezabel Rodriguez; Meltzer, Carin; Einvik, Gunnar; Ueland, Thor; Olsen, Inge Christoffer; Barratt-Due, Andreas; Aaløkken, Trond Mogens; Skjønsberg, Ole Henning (Journal article; Peer reviewed, 2021)The association between pulmonary sequelae and markers of disease severity, as well as pro-fibrotic mediators, were studied in 108 patients 3 months after hospital admission for COVID-19. The COPD assessment test (CAT-score), ... -
Rekonvalesensplasma mot covid-19 fremstilt fra norske blodgivere
Nissen-Meyer, Lise Sofie Haug; Steinsvåg, Christine Torsvik; Fenstad, Mona H.; Sørvoll, Ingvild Hausberg; Hvalryg, Marte; Titze, Thomas Larsen; Magnussen, Karin; Kristoffersen, Gunn; Johnsen, Kathrine M Neuman; LLOHN, ABID HUSSAIN; Hermundstad, Brita; Høiback, Lilja Synnøve; Haugen, Morten; Kristoffersen, Einar Klæboe; Boulland, Line; Kran, Anne-Marte Bakken; Lund-Johansen, Fridtjof; Vaage, John T.; Flesland, Øystein; Hervig, Tor Audun (Journal article; Peer reviewed, 2023)BAKGRUNN Ved pandemiens start tok Helsedirektoratet og norske blodbanker initiativ til produksjon av covid-19-rekonvalesensplasma innenfor rammen av kliniske studier. Her beskriver vi blodgiverne som deltok. MATERIALE ... -
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Holter, Jan Cato; Pischke, Soeren; de Boer, Eline; Lind, Andreas; Jenum, Synne; Holten, Aleksander Rygh; Tonby, Kristian; Barratt-Due, Andreas; Sokolova, Marina; Schjalm, Camilla; Chaban, Viktoriia; Kolderup, Anette; Tran, Trung; Tollefsrud Gjølberg, Torleif; Skeie, Linda Gail; Hesstvedt, Liv; Ormåsen, Vidar; Fevang, Børre; Austad, Cathrine; Muller, Karl Erik; Fladeby, Cathrine; Holberg-Petersen, Mona; Halvorsen, Bente; Müller, Fredrik; Aukrust, Pål; Dudman, Susanne Gjeruldsen; Ueland, Thor; Andersen, Jan Terje; Lund-Johansen, Fridtjof; Heggelund, Lars; Dyrhol-Riise, Anne Ma; Mollnes, Tom Eirik (Journal article; Peer reviewed, 2020)Respiratory failure in the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is hypothesized to be driven by an overreacting innate immune response, where the complement system is a key player. In this prospective ... -
Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
Tran, Trung The; Vaage, Eline Benno; Mehta, Adi; Chopra, Adity; Tietze, Lisa; Kolderup, Anette; Anthi, Aina Karen; König, Marton; Nygaard, Gro Owren; Lind, Andreas; Müller, Fredrik; Nissen-Meyer, Lise Sofie Haug; Magnus, Per Minor; Trogstad, Lill; Mjaaland, Siri; Søraas, Arne Vasli; Midtvedt, Karsten; Åsberg, Anders; Barratt-Due, Andreas; Medhus, Asle Wilhelm; Høivik, Marte Lie; Lundin, Knut; Karlsen, Randi Fuglaas; Dahle, Reidun; Danielsson, Karin; Thomassen, Kristine Stien; Kro, Grete Anette Birkeland; Cox, Rebecca Jane; Zhou, Fan; Langeland, Nina; Aukrust, Pål; Melum, Espen; Åvitsland, Tone Lise; Wiencke, Kristine; Holter, Jan Cato; Munthe, Ludvig Andre; Grødeland, Gunnveig; Andersen, Jan Terje; Vaage, John T.; Lund-Johansen, Fridtjof (Journal article; Peer reviewed, 2022)Diagnostic assays currently used to monitor the efficacy of COVID-19 vaccines measure levels of antibodies to the receptor-binding domain of ancestral SARS-CoV-2 (RBDwt). However, the predictive value for protection against ...