Browsing Bergen Open Research Archive by Author "Lunde, Harald Sæbø"
Now showing items 1-4 of 4
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Evolutionary, comparative, and functional analyses of STATs and regulation of the JAK-STAT pathway in lumpfish upon bacterial and poly(I:C) exposure
Sadashiva Rao, Shreesha; Nelson, Patrick Alexander; Lunde, Harald Sæbø; Haugland, Gyri Teien (Journal article; Peer reviewed, 2023)Background: The Janus kinase/signal transducers and activators of transcription (JAK-STAT) system regulates several biological processes by affecting transcription of genes as a response to cytokines and growth factors. ... -
Interleukin-1 ligands and receptors in lumpfish (Cyclopterus lumpus L.): molecular characterization, phylogeny, gene expression and transcriptome analyses
Eggestøl, Håvard Øritsland; Lunde, Harald Sæbø; Knutsen, Tim Martin; Haugland, Gyri Teien (Journal article; Peer reviewed, 2020-04-02)The interleukin (IL)-1 family play a fundamental role as immune system modulators. Our previous transcriptome-analyses of leukocytes from lumpfish (Cyclopterus lumpus L.) showed that IL-1β was among the most highly upregulated ... -
Neutrophils in Atlantic salmon (Salmo salar L.) are MHC class II+ and secret IL-12p40 upon bacterial exposure
Haugland, Gyri Teien; Rønneseth, Anita; Gundersen, Lene; Lunde, Harald Sæbø; Nordland, Kaja; Wergeland, Heidrun Inger (Journal article; Peer reviewed, 2022)Antigen-presentation via major histocompatibility complex (MHC) to T cells is the key event to initiate adaptive immune responses. In teleosts, as in mammals, the main types of professional antigen-presenting cells (APCs) ... -
Transcriptome-wide analyses of early immune responses in lumpfish leukocytes upon stimulation with poly(I:C)
Sadashiva Rao, Shreesha; Lunde, Harald Sæbø; Dolan, David William Peter; Fond, Amanda Kästel Sandal; Petersen, Kjell; Haugland, Gyri Teien (Journal article; Peer reviewed, 2023)Background: Both bacterial and viral diseases are a major threat to farmed fish. As the antiviral immune mechanisms in lumpfish (Cyclopterus lumpus L.) are poorly understood, lumpfish leukocytes were stimulated with ...