Browsing Bergen Open Research Archive by Author "Lynagh, Timothy Peter"

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Comparative analysis defines a broader FMRFamide-gated sodium channel family and determinants of neuropeptide sensitivity

Dandamudi, Mowgli; Hausen, Harald; Lynagh, Timothy Peter (Journal article; Peer reviewed, 2022)

FMRFamide (Phe-Met-Arg-Phe-amide, FMRFa) and similar neuropeptides are important physiological modulators in most invertebrates, but the molecular basis of FMRFa activity at its receptors is unknown. We therefore sought ...
Peripheral and central employment of acid-sensing ion channels during early bilaterian evolution

Marti Solans, Josep; Børve, Aina; Bump, Paul; Hejnol, Andreas; Lynagh, Timothy Peter (Journal article; Peer reviewed, 2023)

Nervous systems are endowed with rapid chemosensation and intercellular signaling by ligand-gated ion channels (LGICs). While a complex, bilaterally symmetrical nervous system is a major innovation of bilaterian animals, ...