Blar i Bergen Open Research Archive på forfatter "Lyu, Chuang"
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Effect of nerve injury on the number of dorsal root ganglion neurons and autotomy behavior in adult Bax-deficient mice
Lyu, Chuang; Lyu, Gong-Wei; Martinez, Aurora; Shi, Tie-Jun (Peer reviewed; Journal article, 2017-08-30)Background: The proapoptotic molecule BAX, plays an important role in mitochondrial apoptotic pathway. Dorsal root ganglion (DRG) neurons depend on neurotrophic factors for survival at early developmental stages. Withdrawal ... -
Expression and regulation of FRMD6 in mouse DRG neurons and spinal cord after nerve injury
Lyu, Chuang; Lyu, Gong-Wei; Mulder, Jan; Uhlén, Mathias; Cai, Xue-Hui; Hökfelt, Tomas; Shi, Tie-Jun (Journal article; Peer reviewed, 2020)FRMD6, a member of the group of FERM-domain proteins, is involved both in communication between cells, interactions with extracellular matrix, cellular apoptotic and regenerative mechanisms. FRMD6 was first discovered in ... -
G Protein-Gated Inwardly Rectifying Potassium Channel Subunit 3 Is Upregulated in Rat DRGs and Spinal Cord After Peripheral Nerve Injury
Lyu, Chuang; Lyu, Gong-Wei; Mulder, Jan; Martinez, Aurora; Shi, Tie-Jun (Journal article; Peer reviewed, 2020)Background: G protein-gated inwardly rectifying potassium (GIRK) channels are involved in the regulation of neuronal excitability. Four GIRK subunits (GIRK1-4) are expressed in rat dorsal root ganglia (DRGs). Recently, we ... -
Neuronal plasticity of trigeminal ganglia in mice following nerve injury
Lynds, Randi; Lyu, Chuang; Lyu, Gong-Wei; Shi, Xie-Qi; Rosén, Annika; Mustafa, Kamal Babikeir Eln; Shi, Tie-Jun (Peer reviewed; Journal article, 2017-02-09)Background: Nerve injury may induce neuropathic pain. In studying the mechanisms of orofacial neuropathic pain, attention has been paid to the plastic changes that occur in the trigeminal ganglia (TGs) and nucleus in ...