• RAB5A and TRAPPC6B are novel targets for Shiga toxin 2a inactivation in kidney epithelial cells 

      Kouzel, Ivan; Kehl, Alexander; Berger, Petya; Liashkovich, Ivan; Steil, Daniel; Makalowski, Wojciech; Suzuki, Yutaka; Pohlentz, Gottfried; Karch, Helge; Mellmann, Alexander C.; Müthing, Johannes (Journal article; Peer reviewed, 2020-03-18)
      The cardinal virulence factor of human-pathogenic enterohaemorrhagic Escherichia coli (EHEC) is Shiga toxin (Stx), which causes severe extraintestinal complications including kidney failure by damaging renal endothelial ...