Blar i Bergen Open Research Archive på forfatter "Madsen, Andre"
-
Deep phenotyping of pubertal development in Norwegian children: the Bergen Growth Study 2
Juliusson, Petur B.; Bruserud, Ingvild S.; Oehme, Ninnie Helen Bakken; Madsen, Andre; Forthun, Ingvild Halsør; Balthasar, Melissa Rajini; Viste, kristin; Jugessur, Astanand; Schell, Lawrence M.; Bjerknes, Robert; Roelants, Mathieu; Karen, Rosendahl (Journal article; Peer reviewed, 2023)Background The Bergen Growth Study 2 (BGS2) aims to characterise somatic and endocrine changes in healthy Norwegian children using a novel methodology. Subjects and methods A cross-sectional sample of 1285 children ... -
Function and regulation of Steroid Receptor Coactivator 2. Transcriptional regulation of cellular metabolism
Madsen, Andre (Doctoral thesis, 2015-12-18)Nuclear hormone receptors (NRs) associate with coregulators to enable complex programs of gene expression. The p160 steroid receptor coactivator 2 (SRC- 2/GRIP1) regulates metabolism and cellular processes in a tissue-specific ... -
Hormone references for ultrasound breast staging and endocrine profiling to detect female onset of puberty
Madsen, Andre; Bruserud, Ingvild Særvold; Bertelsen, Bjørn-Erik; Roelants, Mathieu; Oehme, Ninnie; Viste, Kristin; Bjerknes, Robert; Almås, Bjørg; Rosendahl, Karen; Mellgren, Gunnar; Sagen, Jørn V.; Juliusson, Petur Benedikt (Journal article; Peer reviewed, 2020)Context Application of ultrasound (US) to evaluate attainment and morphology of glandular tissue provides a new rationale for evaluating onset and progression of female puberty, but currently no hormone references complement ... -
Low BMI, but not high BMI, influences the timing of puberty in boys
Oehme, Ninnie Helen Bakken; Roelants, Mathieu; Bruserud, Ingvild Særvold; Madsen, Andre; Bjerknes, Robert; Rosendahl, Karen; Juliusson, Pétur Benedikt (Journal article; Peer reviewed, 2021)Background Previous studies investigating the association between weight status and onset of puberty in boys have been equivocal. It is currently unclear to what extent weight class influences puberty onset and ... -
Maternal PCOS status and metformin in pregnancy: Steroid hormones in 5–10 years old children from the PregMet randomized controlled study
Hanem, Liv Guro Engen; Salvesen, Øyvind; Madsen, Andre; Sagen, Jørn Vegard; Mellgren, Gunnar; Juliusson, Petur Benedikt; Carlsen, Sven Magnus; Vanky, Eszter; Ødegård, Rønnaug (Journal article; Peer reviewed, 2021)Objective: Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with potential effects on offspring both genetically and through altered intrauterine environment. Metformin, which ameliorate hormonal disturbances ... -
Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2)
Madsen, Andre; Bozickovic, Olivera; Bjune, Jan Inge; Mellgren, Gunnar; Sagen, Jørn V. (Peer reviewed; Journal article, 2015-11-09)The ability of the anti-diabetic drug metformin to inhibit anabolic processes including gluconeogenesis and lipogenesis is partly attributable to activation of the AMP-activated protein kinase (AMPK) pathway. The p160 ... -
Reference curves for pediatric endocrinology: leveraging biomarker z-scores for clinical classifications
Madsen, Andre; Almås, Bjørg; Bruserud, Ingvild Særvold; Oehme, Ninnie Helen Bakken; Nielsen, Christopher Sivert; Roelants, Mathieu; Hundhausen, Thomas Eckhard; Ljubicic, Marie Lindhardt; Bjerknes, Robert; Mellgren, Gunnar; Sagen, Jørn V.; Juliusson, Pétur Benedikt; Viste, Kristin (Journal article; Peer reviewed, 2022)Context Hormone reference intervals in pediatric endocrinology are traditionally partitioned by age and lack the framework for benchmarking individual blood test results as normalized z-scores and plotting sequential ... -
Reference data for testicular volume measured with ultrasound and pubic hair in Norwegian boys are comparable with Northern European populations
Oehme, Ninnie; Roelants, Mathieu; Bruserud, Ingvild Særvold; Madsen, Andre; Eide, Geir Egil; Bjerknes, Robert; Rosendahl, Karen; Juliusson, Petur Benedikt (Peer reviewed; Journal article, 2020)Aim: To estimate references for testicular volume measured with ultrasound and Tanner stages of pubic hair in Norwegian boys, and to compare the timing of puberty with data from similar populations. Methods: Testicular ... -
References for ultrasound staging of breast maturation, tanner breast staging, pubic hair, and menarche in Norwegian girls
Bruserud, Ingvild Særvold; Roelants, Mathieu; Oehme, Ninnie; Madsen, Andre; Eide, Geir Egil; Bjerknes, Robert; Rosendahl, Karen; Juliusson, Petur Benedikt (Journal article; Peer reviewed, 2020)Context: Discriminating adipose and glandular tissue is challenging when clinically assessing breast development. Ultrasound facilitates staging of pubertal breast maturation (US B), but has not been systematically compared ... -
Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer
Moi, Line Leonora Haugan; Flågeng, Marianne Hauglid; Gjerde, Jennifer; Madsen, Andre; Røst, Therese Halvorsen; Gudbrandsen, Oddrun Anita; Lien, Ernst Asbjørn; Mellgren, Gunnar (Peer reviewed; Journal article, 2012-06-15)Background: Steroid receptor coactivators (SRCs) may modulate estrogen receptor (ER) activity and the response to endocrine treatment in breast cancer, in part through interaction with growth factor receptor signaling ... -
Testicular ultrasound to stratify hormone references in a cross-sectional Norwegian study of male puberty
Madsen, Andre; Oehme, Ninnie; Roelants, Mathieu; Bruserud, Ingvild Særvold; Eide, Geir Egil; Viste, Kristin; Bjerknes, Robert; Almås, Bjørg; Rosendahl, Karen; Sagen, Jørn V.; Mellgren, Gunnar; Juliusson, Petur Benedikt (Peer reviewed; Journal article, 2020)Context: Testicular growth represents the best clinical variable to evaluate male puberty, but current pediatric hormone references are based on chronological age and subjective assessments of discrete puberty development ...