Blar i Bergen Open Research Archive på forfatter "Magnus, Per Minor"
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Acetaminophen use during pregnancy and offspring attention deficit hyperactivity disorder - a longitudinal sibling control study
Gustavson, Kristin; Ystrøm, Eivind; Ask, Helga; Torvik, Fartein Ask; Hornig, Mady; Susser, Ezra; Lipkin, Ian; Lupattelli, Angela; Stoltenberg, Camilla; Magnus, Per Minor; Mjaaland, Siri; Askeland, Ragna Bugge; Walle, Kjersti Mæhlum; Bresnahan, Michaeline; Nordeng, Hedvig Marie Egeland; Reichborn-Kjennerud, Ted (Journal article, 2021)Background: Maternal acetaminophen use during pregnancy is associated with increased risk of ADHD in the child. This could reflect causal influence of acetaminophen on fetal neurodevelopment or could be due to confounding ... -
Age and sex effects on DNA methylation sites linked to genes implicated in severe COVID-19 and SARS-CoV-2 host cell entry
Bohlin, Jon; Page, Christian Magnus; Lee, Yunsung; Pettersson, John H.-O.; Jugessur, Astanand; Magnus, Per Minor; Håberg, Siri Eldevik (Journal article; Peer reviewed, 2022)Male sex and advanced age are associated with severe symptoms of COVID-19. Sex and age also exhibit substantial associations with genome-wide DNA methylation (DNAm) differences in humans. Using a random sample of Illumina ... -
Associations between epigenetic age acceleration and infertility
Lee, Yunsung; Bohlin, Jon; Page, Christian Magnus; Nustad, Haakon E.; Harris, Jennifer Ruth; Magnus, Per Minor; Magnus, Per; Jugessur, Astanand; Magnus, Maria Christine; Håberg, Siri Eldevik; Hanevik, Hans Ivar (Journal article; Peer reviewed, 2022)Study question: Is the use of ART, a proxy for infertility, associated with epigenetic age acceleration? Summary answer: The epigenetic age acceleration measured by Dunedin Pace of Aging methylation (DunedinPoAm) differed ... -
Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study
Hughes, Amanda M.; Sanderson, Eleanor; Morris, Tim; Ayorech, Ziada; Tesli, Martin Steen; Ask, Helga; Reichborn-Kjennerud, Ted; Andreassen, Ole; Magnus, Per Minor; Helgeland, Øyvind; Johansson, Stefan; Njølstad, Pål Rasmus; Davey Smith, George; Havdahl, Alexandra Karoline Saasen; Howe, Laura D.; Davies, Neil Martin (Journal article; Peer reviewed, 2022)Background: Higher BMI in childhood is associated with emotional and behavioural problems, but these associations may not be causal. Results of previous genetic studies imply causal effects but may reflect influence of ... -
Characterization of the genetic architecture of infant and early childhood body mass index
Helgeland, Øyvind; Vaudel, Marc; Sole-Navais, Pol; Flatley, Christopher; Juodakis, Julius; Bacelis, Jonas; Koløen, Ingvild; Knudsen, Gun Peggy Strømstad; Johansson, Bente Berg; Magnus, Per Minor; Reichborn-Kjennerud, Ted; Juliusson, Pétur Benedikt; Stoltenberg, Camilla; Holmen, Oddgeir Lingaas; Andreassen, Ole; Jacobsson, Bo; Njølstad, Pål Rasmus; Johansson, Stefan (Journal article; Peer reviewed, 2022)Early childhood obesity is a growing global concern; however, the role of common genetic variation on infant and child weight development is unclear. Here, we identify 46 loci associated with early childhood body mass index ... -
Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations
Unnarsdóttir, Anna Bára; Lovik, Anikó; Fawns-Ritchie, Chloe; Ask, Helga; Kõiv, Kadri; Hagen, Kristen; Didriksen, Maria; Christoffersen, Lea Arregui Nordahl; Garðarsson, Alexander Berg; McIntosh, Andrew; Kähler, Anna K.; Campbell, Archie; Hauksdóttir, Arna; Erikstrup, Christian; Mikkelsen, Dorte Helenius; Altschul, Drew; Thordardottir, Edda Bjork; Frans, Emma Maria; Kvale, Gerd; Tómasson, Gunnar; Kariis, Hanna Maria; Jónsdóttir, Harpa Lind; Rúnarsdóttir, Harpa; Magnúsdóttir, Ingibjörg; Eid, Jarle; Jakobsdóttir, Jóhanna; Nielsen, Kaspar René; Kaspersen, Kathrine Agergård; Milani, Lili; Trogstad, Lill-Iren Schou; Yi, Lu; Bruun, Mie Topholm; Sullivan, Patrick F.; Magnus, Per Minor; Shen, Qing; Nesvåg, Ragnar; Brandlistuen, Ragnhild Eek; Mägi, Reedik; Ostrowski, Sisse Rye; Løkhammer, Solveig; Solem, Stian; Reichborn-Kjennerud, Ted; Hansen, Thomas Folkmann; Werge, Thomas; Aspelund, Thor; Porteous, David J.; Fang, Fang; Lehto, Kelli; Andreassen, Ole; Pedersen, Ole Birger Vesterager; Hellard, Stephanie Francoise Claire Le; Valdimarsdóttir, Unnur Anna (Journal article; Peer reviewed, 2021) -
DNA methylation in newborns conceived by assisted reproductive technology
Håberg, Siri Eldevik; Page, Christian Magnus; Lee, Yunsung; Nustad, Haakon Egdetveit; Magnus, Maria Christine; Haftorn, Kristine Løkås; Carlsen, Ellen Øen; Denault, William Robert Paul; Bohlin, Jon; Jugessur, Astanand; Magnus, Per Minor; Gjessing, Håkon Kristian; Lyle, Robert (Journal article; Peer reviewed, 2022)Assisted reproductive technology (ART) may affect fetal development through epigenetic mechanisms as the timing of ART procedures coincides with the extensive epigenetic remodeling occurring between fertilization and embryo ... -
Do environmental effects indexed by parental genetic variation influence common psychiatric symptoms in childhood?
Jami, Eshim S.; Hammerschlag, Anke R.; Sallis, Hannah M.; Qiao, Zhen; Andreassen, Ole A.; Magnus, Per Minor; Njølstad, Pål Rasmus; Havdahl, Alexandra; Pingault, Jean-Baptiste; Evans, David M.; Munafò, Marcus R.; Ystrom, Eivind; Bartels, Meike; Middeldorp, Christel (Journal article; Peer reviewed, 2023)Parental genes may indirectly influence offspring psychiatric outcomes through the environment that parents create for their children. These indirect genetic effects, also known as genetic nurture, could explain individual ... -
Do Genetic Variants Modify the Effect of Smoking on Risk of Preeclampsia in Pregnancy?
Bauer, Anna E.; Avery, Christy L.; Shi, Min; Weinberg, Clarice R.; Olshan, Andrew F.; Harmon, Quaker E.; Luo, Jingchun; Yang, Jenny; Manuck, Tracy; Wu, Michael C.; Klungsøyr, Kari; Trogstad, Lill; Magnus, Per Minor; Engel, Stephanie M. (Journal article; Peer reviewed, 2021)Objective: Maternal smoking is associated with as much as a 50% reduced risk of preeclampsia, despite increasing risk of other poor pregnancy outcomes that often co-occur with preeclampsia, such as preterm birth and fetal ... -
Early manifestations of genetic risk for neurodevelopmental disorders
Askeland, Ragna Bugge; Hannigan, Laurie J.; Ask, Helga; Ayorech, Ziada; Tesli, Martin Steen; Corfield, Elizabeth; Magnus, Per Minor; Njølstad, Pål Rasmus; Andreassen, Ole A.; Smith, George Davey; Reichborn-Kjennerud, Ted; Havdahl, Alexandra (Journal article; Peer reviewed, 2021)Background: Attention deficit/hyperactivity disorder (ADHD), autism spectrum disorder (autism) and schizophrenia are highly heritable neurodevelopmental disorders, affecting the lives of many individuals. It is important ... -
The educational burden of disease: a cohort study
Nordmo, Magnus; Kinge, Jonas Minet; Reme, Bjørn-Atle; Flatø, Martin; Suren, Pål; Wörn, Jonathan; Magnus, Per Minor; Stoltenberg, Camilla; Torvik, Fartein Ask (Journal article; Peer reviewed, 2022)Background Students with health disorders might be at risk of disengaging from education, which can reinforce socioeconomic inequalities in health. We aimed to evaluate the associations between 176 diseases and injuries ... -
Effectiveness of mRNA booster vaccination against mild, moderate, and severe COVID-19 caused by the Omicron variant in a large, population-based, Norwegian cohort
Laake, Ida; Skodvin, Siri Nærland; Blix, Kristine; Caspersen, Ida Henriette; Gjessing, Håkon K.; Juvet, Lene Kristine; Magnus, Per Minor; Mjaaland, Siri; Robertson, Anna Hayman; Starrfelt, Jostein; Trogstad, Lill; Feiring, Berit (Journal article; Peer reviewed, 2022)Background Understanding how booster vaccination can prevent moderate and severe illness without hospitalization is crucial to evaluate the full advantage of mRNA boosters. Methods We followed 85 801 participants (aged ... -
An EPIC predictor of gestational age and its application to newborns conceived by assisted reproductive technologies
Haftorn, Kristine Løkås; Lee, Yunsung; Denault, William Robert Paul; Page, Christian Magnus; Nustad, Haakon Egdetveit; Lyle, Robert; Gjessing, Håkon Kristian; Malmberg, Anni; Magnus, Maria Christine; Næss, Øyvind; Czamara, Darina; Räikkönen, Katri; Lahti, Jari; Magnus, Per Minor; Håberg, Siri Eldevik; Jugessur, Astanand; Bohlin, Jon (Journal article; Peer reviewed, 2021)Background: Gestational age is a useful proxy for assessing developmental maturity, but correct estimation of gestational age is difficult using clinical measures. DNA methylation at birth has proven to be an accurate ... -
An examination of mediation by DNA methylation on birthweight differences induced by assisted reproductive technologies
Carlsen, Ellen Øen; Lee, Yunsung; Magnus, Per Minor; Jugessur, Astanand; Page, Christian Magnus; Nustad, Haakon Egdetveit; Håberg, Siri Eldevik; Lie, Rolv Terje; Magnus, Maria Christine (Journal article; Peer reviewed, 2022)Background Children born after assisted reproductive technologies (ART) differ in birthweight from those naturally conceived. It has been hypothesized that this might be explained by epigenetic mechanisms. We examined ... -
Genetic association study of childhood aggression across raters, instruments, and age
Ip, Hill F.; van der Laan, Camiel M.; Krapohl, Eva M. L.; Brikell, Isabell; Sánchez-Mora, Cristina; Nolte, Ilja M.; Pourcain, Beate St; Bolhuis, Koen; Palviainen, Teemu; Zafarmand, Hadi; Colodro-Conde, Lucía; Gordon, Scott; Zayats, Tetyana; Aliev, Fazil; Jiang, Chang; Wang, Carol A.; Saunders, Gretchen; Karhunen, Ville; Hammerschlag, Anke R.; Adkins, Daniel E.; Border, Richard; Peterson, Roseann E.; Prinz, Joseph A.; Thiering, Elisabeth; Seppälä, Iikka; Vilor-Tejedor, Natàlia; Ahluwalia, Tarunveer S.; Day, Felix R.; Hottenga, Jouke-Jan; Allegrini, Andrea G.; Rimfeld, Kaili; Chen, Qi; Yi, Lu; Martin, Joanna; Soler Artigas, Marìa; Rovira, Paula; Bosch, Rosa; Español, Gemma; Ramos-Quiroga, Josep Antonio; Neumann, Alexander; Haavik, Jan; Harris, Jennifer Ruth; Helgeland, Øyvind; Johansson, Stefan; Knudsen, Gun Peggy Strømstad; Njølstad, Pål Rasmus; Havdahl, Alexandra; Magnus, Per Minor; Reichborn-Kjennerud, Ted; Boomsma, Dorret I. (Journal article; Peer reviewed, 2021)Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from ... -
Genetic effects on the timing of parturition and links to fetal birth weight
Solé-Navais, Pol; Flatley, Christopher; Steinthorsdottir, Valgerdur; Vaudel, Marc; Juodakis, Julius; Chen, Jing; Laisk, Triin; LaBella, Abigail L.; Westergaard, David; Bacelis, Jonas; Brumpton, Ben Michael; Skotte, Line; Borges, Maria C.; Helgeland, Øyvind; Mahajan, Anubha; Wielscher, Matthias; Lin, Frederick; Briggs, Catherine; Wang, Carol A.; Moen, Gunn-Helen Øiseth; Beaumont, Robin N.; Bradfield, Jonathan P.; Abraham, Abin; Thorleifsson, Gudmar; Gabrielsen, Maiken Elvestad; Ostrowski, Sisse R.; Modzelewska, Dominika; Nøhr, Ellen Aagaard; Hypponen, Elina; Srivastava, Amit; Talbot, Octavious; Allard, Catherine; Williams, Scott M.; Menon, Ramkumar; Shields, Beverley M.; Sveinbjornsson, Gardar; Xu, Huan; Melbye, Mads; Lowe, William; Bouchard, Luigi; Oken, Emily; Pedersen, Ole B.; Gudbjartsson, Daniel F.; Erikstrup, Christian; Sørensen, Erik; Lie, Rolv T.; Teramo, Kari; Hallman, Mikko; Juliusdottir, Thorhildur; Hakonarson, Hakon; Ullum, Henrik; Hattersley, Andrew T.; Sletner, Line; Merialdi, Mario; Rifas-Shiman, Sheryl L.; Steingrimsdottir, Thora; Scholtens, Denise; Power, Christine; West, Jane; Nyegaard, Mette; Capra, John A.; Skogholt, Anne Heidi; Magnus, Per Minor; Andreassen, Ole; Thorsteinsdottir, Unnur; Grant, Struan F. A.; Qvigstad, Elisabeth; Pennell, Craig E.; Hivert, Marie-France; Hayes, Geoffrey M.; Jarvelin, Marjo-Riitta; McCarthy, Mark I.; Lawlor, Deborah A.; Nielsen, Henriette S.; Mägi, Reedik; Rokas, Antonis; Hveem, Kristian; Stefansson, Kari; Feenstra, Bjarke; Njølstad, Pål Rasmus; Muglia, Louis J.; Freathy, Rachel M.; Johansson, Stefan; Zhang, Ge; Jacobsson, Bo (Journal article; Peer reviewed, 2023)The timing of parturition is crucial for neonatal survival and infant health. Yet, its genetic basis remains largely unresolved. We present a maternal genome-wide meta-analysis of gestational duration (n = 195,555), ... -
Genome-wide association meta-analysis of childhood and adolescent internalizing symptoms
Jami, Eshim S.; Hammerschlag, Anke R.; Ip, Hill F.; Allegrini, Andrea G.; Benyamin, Beben; Border, Richard; Diemer, Elizabeth W.; Jiang, Chang; Karhunen, Ville; Lu, Yi; Lu, Qing; Mallard, Travis T.; Mishra, Pashupati P.; Nolte, Ilja M.; Palviainen, Teemu; Peterson, Roseann E.; Sallis, Hannah M.; Shabalin, Andrey A.; Tate, Ashley E.; Thiering, Elisabeth; Vilor-Tejedor, Natàlia; Wang, Carol; Zhou, Ang; Adkins, Daniel E.; Alemany, Silvia; Ask, Helga; Chen, Qi; Corley, Robin P.; Ehli, Erik A.; Evans, Luke M.; Havdahl, Alexandra; Hagenbeek, Fiona A.; Hakulinen, Christian; Henders, Anjali K.; Hottenga, Jouke Jan; Korhonen, Tellervo; Mamun, Abdullah; Marrington, Shelby; Neumann, Alexander; Rimfeld, Kaili; Rivadeneira, Fernando; Silberg, Judy L.; van Beijsterveldt, Catharina E.; Vuoksimaa, Eero; Whipp, Alyce M.; Tong, Xiaoran; Andreassen, Ole; Boomsma, Dorret I.; Brown, Sandra A.; Burt, S. Alexandra; Copeland, William; Dick, Danielle M.; Harden, K. Paige; Harris, Kathleen Mullan; Hartman, Catharina A.; Heinrich, Joachim; Hewitt, John K.; Hopfer, Christian; Hypponen, Elina; Jarvelin, Marjo-Riitta; Kaprio, Jaakko; Keltikangas-Järvinen, Liisa; Klump, Kelly L.; Krauter, Kenneth; Kuja-Halkola, Ralf; Larsson, Henrik; Lehtimäki, Terho; Lichtenstein, Paul; Lundström, Sebastian; Maes, Hermine H.; Magnus, Per Minor; Munafò, Marcus R.; Najman, Jake M.; Njølstad, Pål Rasmus; Oldehinkel, Albertine J.; Pennell, Craig E.; Plomin, Robert; Reichborn-Kjennerud, Ted; Reynolds, Chandra; Rose, Richard J.; Smolen, Andrew; Snieder, Harold; Stallings, Michael; Standl, Marie; Sunyer, Jordi; Tiemeier, Henning; Wadsworth, Sally J.; Wall, Tamara L.; Whitehouse, Andrew J.O.; Williams, Gail M.; Ystrøm, Eivind; Nivard, Michel G.; Bartels, Meike; Middeldorp, Christel M. (Journal article; Peer reviewed, 2022)Objective: To investigate the genetic architecture of internalizing symptoms in childhood and adolescence. Method: In 22 cohorts, multiple univariate genome-wide association studies (GWASs) were performed using repeated ... -
A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans
Moksnes, Marta Riise; Hansen, Ailin Falkmo; Wolford, Brooke; Thomas, Laurent Francois; Rasheed, Humaira; Simic, Anica; Bhatta, Laxmi; Brantsæter, Anne Lise; Surakka, Ida; Zhou, Wei; Magnus, Per Minor; Njølstad, Pål Rasmus; Andreassen, Ole; Syversen, Tore; Zheng, Jie; Fritsche, Lars; Evans, David M.; Warrington, Nicole Maree; Nøst, Therese Haugdahl; Åsvold, Bjørn Olav; Flaten, Trond Peder; Willer, Cristen J.; Hveem, Kristian; Brumpton, Ben Michael (Journal article; Peer reviewed, 2024)Trace elements are important for human health but may exert toxic or adverse effects. Mechanisms of uptake, distribution, metabolism, and excretion are partly under genetic control but have not yet been extensively mapped. ... -
Impaired glucose tolerance and cardiovascular risk factors in relation to infertility: a Mendelian randomization analysis in the Norwegian Mother, Father, and Child Cohort Study
Hernáez, Álvaro; Lee, Yunsung; Page, Christian Magnus; Skåra, Karoline Hansen; Håberg, Siri Eldevik; Magnus, Per Minor; Njølstad, Pål Rasmus; Andreassen, Ole; Corfield, Elizabeth Claire; Havdahl, Alexandra; Fraser, Abigail; Burgess, Stephen; Lawlor, Deborah A.; Magnus, Maria Christine (Journal article; Peer reviewed, 2024)Study question: Are impaired glucose tolerance (as measured by fasting glucose, glycated hemoglobin, and fasting insulin) and cardiovascular disease risk (as measured by low-density lipoprotein cholesterol, high-density ... -
The influence of immigrant background and parental education on overweight and obesity in 8-year-old children in Norway
Øvrebø, Bente; Kjøllesdal, Marte Karoline Råberg; Stea, Tonje Holte; Wills, Andrew Keith; Bere, Elling Tufte; Magnus, Per Minor; Juliusson, Pétur Benedikt; Bergh, Ingunn Holden (Journal article; Peer reviewed, 2023)Background Little is known about the prevalence of overweight/obesity and socio-economic position (SEP) in children with immigrant background in Scandinavia. The purpose of this study is to examine the prevalence of ...