Browsing Bergen Open Research Archive by Author "Major, Diane"
Now showing items 1-2 of 2
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Intranasal vaccination with a plant-derived H5 HA vaccine protects mice and ferrets against highly pathogenic avian influenza virus challenge
Major, Diane; Chichester, Jessica A.; Pathirana, Rishi; Guilfoyle, Kate; Shoji, Yoko; Guzman, Carlos A.; Yusibov, Vidadi; Cox, Rebecca Jane (Peer reviewed; Journal article, 2015-05)Highly pathogenic avian influenza H5N1 infection remains a public health threat and vaccination is the best measure of limiting the impact of a potential pandemic. Mucosal vaccines have the advantage of eliciting immune ... -
Matrix M H5N1 vaccine induces cross-H5 clade humoral immune responses in a randomized clinical trial and provides protection from highly pathogenic influenza challenge in ferrets
Cox, Rebecca Jane; Major, Diane; Pedersen, Gabriel Kristian; Pathirana, Rishi; Höschler, Katja; Guilfoyle, Kate; Roseby, Sarah; Bredholt, Geir; Assmus, Jörg; Breakwell, Lucy; Campitelli, Laura; Sjursen, Haakon (Peer reviewed; Journal article, 2015-07-06)Background and Methods: Highly pathogenic avian influenza (HPAI) viruses constitute a pandemic threat and the development of effective vaccines is a global priority. Sixty adults were recruited into a randomized clinical ...